- An injectable, in situ enzymatically gellable, gelatin derivative for drug delivery and tissue engineering
[作者:Sakai, S; Hirose, K; Taguchi, K; Ogushi, Y; Kawakami, K,期刊:BIOMATERIALS, 页码:3371-3377 , 文章类型: Article,,卷期:2009年30-20]
- A phenolic hydroxyl group was incorporated into gelatin, using aqueous-phase carbodiimide activation chemistry, to obtain in situ gellable and injectable protein-based materials for drug delivery and tissue engineering a...
- Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation
[作者:Redenti, S; Neeley, WL; Rompani, S; Saigal, S; Yang, J; Klassen, H; Langer, R; Young, MJ,期刊:BIOMATERIALS, 页码:3405-3414 , 文章类型: Article,,卷期:2009年30-20]
- Retinal degenerations cause permanent visual loss and affect millions world-wide. Presently, a novel treatment highlights the potential of using biodegradable polymer scaffolds to induce differentiation and deliver retin...
- The effect of ultra-nanocrystalline diamond films on the proliferation and differentiation of neural stem cells
[作者:Chen, YC; Lee, DC; Hsiao, CY; Chung, YF; Chen, HC; Thomas, JP; Pong, WF; Tai, NH; Lin, IN; Chiu, IM,期刊:BIOMATERIALS, 页码:3428-3435 , 文章类型: Article,,卷期:2009年30-20]
- The interaction of ultra-nanocrystalline diamond (UNCD) with neural stem cells (NSCs) has been studied along with its surface modification in order to improve its function as a biomaterial. Hydrogen- and oxygen-terminate...
- Positioning and guidance of neurons on gold surfaces by directed assembly of proteins using Atomic Force Microscopy
[作者:Staii, C; Viesselmann, C; Ballweg, J; Shi, LF; Liu, GY; Williams, JC; Dent, EW; Coppersmith, SN; Eriksson, MA,期刊:BIOMATERIALS, 页码:3397-3404 , 文章类型: Article,,卷期:2009年30-20]
- We demonstrate that Atomic Force Microscopy nanolithography can be used to control effectively the adhesion, growth and interconnectivity of cortical neurons on Au surfaces. We demonstrate immobilization of neurons at we...
- An embolic gelling solution based on acrylic copolymers in ethanol for the treatment of arteriovenous malformations
[作者:Seron, A; Moine, L; Laurent, A; Wassef, M; Guiffant, G; Flaud, P; Labarre, D,期刊:BIOMATERIALS, 页码:3436-3443 , 文章类型: Article,,卷期:2009年30-20]
- We report the preparation of an embolic agent based on specific association of an acrylic copolymer with dedicated particles formulated in ethanol. The copolymers were synthesized by radical polymerization of tertiobutyl...
- Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers
[作者:Lammers, T; Subr, V; Ulbrich, K; Peschke, P; Huber, PE; Hennink, WE; Storm, G,期刊:BIOMATERIALS, 页码:3466-3475 , 文章类型: Article,,卷期:2009年30-20]
- Copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) are prototypic and well-characterized polymeric drug carriers that have been broadly implemented in the delivery of anticancer therapeutics. To demonstrate that poly...
- Cryopreservation based on freezing protocols for the long-term storage of microencapsulated myoblasts
[作者:Murua, A; Orive, G; Hernandez, RM; Pedraz, JL,期刊:BIOMATERIALS, 页码:3495-3501 , 文章类型: Article,,卷期:2009年30-20]
- One important challenge in biomedicine is the ability to cryogenically preserve not only cells, but also tissue-engineered constructs. In the present paper, alginate-poly-L-lysine-alginate (APA) microcapsules containing ...
- N-acetyl cysteine (NAC)-mediated detoxification and functionalization of poly(methyl methacrylate) bone cement
[作者:Tsukimura, N; Yamada, M; Aita, H; Hori, N; Yoshino, F; Lee, MCI; Kimoto, K; Jewett, A; Ogawa, T,期刊:BIOMATERIALS, 页码:3378-3389 , 文章类型: Article,,卷期:2009年30-20]
- Currently used poly(methyl methacrylate) (PMMA)-based bone cement lacks osteoconductivity and induces osteolysis and implant loosening due to its cellular and tissue-toxicity. A high percentage of revision surgery follow...
- Mechanisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces
[作者:Schwartz, Z; Olivares-Navarrete, R; Wieland, M; Cochran, DL; Boyan, BD,期刊:BIOMATERIALS, 页码:3390-3396 , 文章类型: Article,,卷期:2009年30-20]
- Osteoblasts grown on microstructured Ti surfaces enhance osteointegration by producing local factors that regulate bone formation as well as bone remodeling, including the RANK ligand decoy receptor osteoprotegerin (OPG)...
- The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering
[作者:Pytlik, R; Stehlik, D; Soukup, T; Kalbacova, M; Rypacek, F; Trc, T; Mulinkova, K; Michnova, P; Kideryova, L; Zivny, J; Klener, P; Vesela, R; Trneny, M; Klener, P,期刊:BIOMATERIALS, 页码:3415-3427 , 文章类型: Article,,卷期:2009年30-20]
- Clinical application of human multipotent mesenchymal stromal cells (hMSCs) requires their expansion to be safe and rapid. We aimed to develop an expansion protocol which would avoid xenogeneic proteins, including fetal ...
- The use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalation
[作者:Tseng, CL; Su, WY; Yen, KC; Yang, KC; Lin, FH,期刊:BIOMATERIALS, 页码:3476-3485 , 文章类型: Article,,卷期:2009年30-20]
- To develop a polymer-anti cancer drug conjugate, we employed gelatin nanoparticles (GPs) as carriers of cisplatin (CDDP) with anticipated improved therapeutic effect and reduced side effects. The anticancer activities of...
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