- A double-chamber rotating bioreactor for the development of tissue-engineered hollow organs: From concept to clinical trial
[作者:Asnaghi, MA; Jungebluth, P; Raimondi, MT; Dickinson, SC; Rees, LEN; Go, T; Cogan, TA; Dodson, A; Parnigotto, PP; Hollander, AP; Birchall, MA; Conconi, MT; Macchiarini, P; Mantero, S,期刊:BIOMATERIALS, 页码:5260-5269 , 文章类型: Editorial Material,,卷期:2009年30-29]
- Cell and tissue engineering are now being translated into clinical organ replacement, offering alternatives to fight morbidity, organ shortages and ethico-social problems associated with allotransplantation. Central to t...
- Strategies for inducing the formation of bands of Bungner in peripheral nerve regeneration
[作者:Ribeiro-Resende, VT; Koenig, B; Nichterwitz, S; Oberhoffner, S; Schlosshauer, B,期刊:BIOMATERIALS, 页码:5251-5259 , 文章类型: Editorial Material,,卷期:2009年30-29]
- Peripheral human nerves fail to regenerate across longer tube implants (>2 cm), most likely because implants lack the microarchitecture of native nerves, including bands of Bungner. Bands of Bungner comprise longitudinal...
- Skeletal muscle cell proliferation and differentiation on polypyrrole substrates doped with extracellular matrix components
[作者:Gilmore, KJ; Kita, M; Han, Y; Gelmi, A; Higgins, MJ; Moulton, SE; Clark, GM; Kapsa, R; Wallace, GG,期刊:BIOMATERIALS, 页码:5292-5304 , 文章类型: Article,,卷期:2009年30-29]
- Conducting polymers have been developed as substrates for in vitro studies with a range of cell types including electrically-excitable cells such as nerve and smooth muscle. The goal of this study was to optimise and cha...
- Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization
[作者:Bencherif, SA; Siegwart, DJ; Srinivasan, A; Horkay, F; Hollinger, JO; Washburn, NR; Matyjaszewski, K,期刊:BIOMATERIALS, 页码:5270-5278 , 文章类型: Article,,卷期:2009年30-29]
- A new method to prepare nanostructured hybrid hydrogels by incorporating well-defined poly(oligo (ethylene oxide) monomethyl ether methacrylate) (POEO(300)MA) nanogels of sizes 110-120 nm into a larger three-dimensional ...
- Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery
[作者:Yin, LC; Ding, JY; He, CB; Cui, LM; Tang, C; Yin, CH,期刊:BIOMATERIALS, 页码:5691-5700 , 文章类型: Article,,卷期:2009年30-29]
- Trimethyl chitosan-cysteine conjugate (TMC-Cys) was synthesized in an attempt to combine the mucoadhesion and the permeation enhancing effects of TMC and thiolated polymers related to different mechanisms for oral absorp...
- The assembly of a short linear natural cytosine-phosphate-guanine DNA into dendritic structures and its effect on immunostimulatory activity
[作者:Rattanakiat, S; Nishikawa, M; Funabashi, H; Luo, D; Takakura, Y,期刊:BIOMATERIALS, 页码:5701-5706 , 文章类型: Article,,卷期:2009年30-29]
- DNA containing unmethylated CpG dinucleotides, or CpG motifs, (CpG DNA) has been explored as a therapeutic agent, owing to its potent immunostimulatory activity. A previous study showing that Y-shaped (Y-) CpG DNA has a ...
- The uptake of N-(2-hydroxypropyl)-methacrylamide based homo, random and block copolymers by human multi-drug resistant breast adenocarcinoma cells
[作者:Barz, M; Luxenhofer, R; Zentel, R; Kabanov, AV,期刊:BIOMATERIALS, 页码:5682-5690 , 文章类型: Article,,卷期:2009年30-29]
- A series of well-defined, fluorescently labelled homopolymers, random and block copolymers based on N-(2-hydroxypropyl)-methacrylamide were prepared by reversible addition-fragmentation chain transfer polymerization (RAF...
- Nanodiamond-insulin complexes as pH-dependent protein delivery vehicles
[作者:Shimkunas, RA; Robinson, E; Lam, R; Lu, S; Xu, XY; Zhang, XQ; Huang, HJ; Osawa, E; Ho, D,期刊:BIOMATERIALS, 页码:5720-5728 , 文章类型: Article,,卷期:2009年30-29]
- Enhanced specificity in drug delivery aims to improve upon systemic elution methods by locally concentrating therapeutic agents and reducing negative side effects. Due to their robust physical properties, biocompatibilit...
- The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator
[作者:Kim, JY; Kim, JK; Park, JS; Byun, Y; Kim, CK,期刊:BIOMATERIALS, 页码:5751-5756 , 文章类型: Article,,卷期:2009年30-29]
- Tissue plasminogen activator (tPA), a widely used thrombolytic agent, has an application limit due to short half-life. To prolong the half-life of tPA, liposomes composed of egg phosphatidylcholine (EPC), cholesterol (CH...
- Proinflammatory and osteoclastogenic effects of beta-tricalciumphosphate and hydroxyapatite particles on human mononuclear cells in vitro
[作者:Lange, T; Schilling, AF; Peters, F; Haag, F; Morlock, MM; Rueger, JM; Amling, M,期刊:BIOMATERIALS, 页码:5312-5318 , 文章类型: Article,,卷期:2009年30-29]
- Particulate wear debris can activate defence cells and osteoclasts at the bone-implant inter-face possibly leading to bone resorption and implant failure. Cellular responses and inflammatory effects have been reported fo...
- Polyethylenimine coating to produce serum-resistant baculoviral vectors for in vivo gene delivery
[作者:Yang, Y; Lo, SL; Yang, JY; Yang, J; Goh, SSL; Wu, CX; Feng, SS; Wang, S,期刊:BIOMATERIALS, 页码:5767-5774 , 文章类型: Article,,卷期:2009年30-29]
- Recombinant baculoviral vectors efficiently transduce many types of mammalian cells. However, their in vivo applications are hampered by the sensitivity of the virus to complement-mediated inactivation. Based on our obse...
- Bioengineered silk protein-based gene delivery systems
[作者:Numata, K; Subramanian, B; Currie, HA; Kaplan, DL,期刊:BIOMATERIALS, 页码:5775-5784 , 文章类型: Article,,卷期:2009年30-29]
- Silk proteins self-assemble into mechanically robust material structures that are also biodegradable and non-cytotoxic, suggesting utility for gene delivery. Since silk proteins can also be tailored in terms of chemistry...
- Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery
[作者:Prabaharan, M; Grailer, JJ; Pilla, S; Steeber, DA; Gong, SQ,期刊:BIOMATERIALS, 页码:5757-5766 , 文章类型: Article,,卷期:2009年30-29]
- Folate-conjugated unimolecular micelles based on amphiphilic hyperbranched block copolymer, Boltorn (R) H40-Poly(L-aspartate-doxorubicin)-b-poly(ethylene glycol)/FA-conjugated poly(ethylene glycol) (H40-P(LA-DOX)-b-PEG-O...
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