- Controlled presentation of recombinant proteins via a zinc-binding peptide-linker in two and three dimensional formats
[作者:Doran, MR; Markway, BD; Croll, TI; Sara, S; Munro, TP; Cooper-White, JJ,期刊:BIOMATERIALS, 页码:6614-6620 , 文章类型: Article,,卷期:2009年30-34]
- The presentation of proteins on surfaces is fundamental to numerous cell culture and tissue engineering applications. While a number of physisorption and cross-linking methods exist to facilitate this process, few avoid ...
- The presence of both bone sialoprotein-binding protein gene and collagen adhesin gene as a typical virulence trait of the major epidemic cluster in isolates from orthopedic implant infections
[作者:Campoccia, D; Speziale, P; Ravaioli, S; Cangini, I; Rindi, S; Pirini, V; Montanaro, L; Arciola, CR,期刊:BIOMATERIALS, 页码:6621-6628 , 文章类型: Article,,卷期:2009年30-34]
- Staphylococcus aureus is a major, highly clonal, pathogen causing implant infections. This study aimed at investigating the diverse distribution of bacterial adhesins in most prevalent S. aureus strain types causing orth...
- The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF
[作者:Shibata, H; Yoshioka, Y; Abe, Y; Ohkawa, A; Nomura, T; Minowa, K; Mukai, Y; Nakagawa, S; Taniai, M; Ohta, T; Kamada, H; Tsunoda, S; Tsutsumi, Y,期刊:BIOMATERIALS, 页码:6638-6647 , 文章类型: Article,,卷期:2009年30-34]
- Blocking the binding of TNF-alpha to TNF receptor subtype-1 (TNFR1) is an important strategy for the treatment of rheumatoid arthritis (RA). We recently succeeded in developing a TNFR1-selective antagonistic TNF mutant, ...
- The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin
[作者:Chen, MC; Wong, HS; Lin, KJ; Chen, HL; Wey, SP; Sonaje, K; Lin, YH; Chu, CY; Sung, HW,期刊:BIOMATERIALS, 页码:6629-6637 , 文章类型: Article,,卷期:2009年30-34]
- Heparin is a potent anticoagulant; however, it is poorly absorbed in the gastrointestinal tract. In this study, we developed a nanoparticle (NP) system shelled with chitosan (CS) for oral delivery of heparin; the NPs wer...
- The characteristics and transfection efficiency of cationic poly (ester-co-urethane) - short chain PEI conjugates self-assembled with DNA
[作者:Liu, XY; Ho, WY; Hung, WJ; Shau, MD,期刊:BIOMATERIALS, 页码:6665-6673 , 文章类型: Article,,卷期:2009年30-34]
- To improve the transfection efficiency of polycations with DNA, we synthesized poly(ester-co-urethane)(PEU-g-PE1800) with short chain PE1800 in the side chain, and poly(ester-co-urethane)(PEU) without short chain PE1800....
- On the effect of substrate curvature on cell mechanics
[作者:Sanz-Herrera, JA; Moreo, P; Garcia-Aznar, JM; Doblare, M,期刊:BIOMATERIALS, 页码:6674-6686 , 文章类型: Article,,卷期:2009年30-34]
- Cell movement on a substrate or within the extracellular matrix is the phenomenological response to a biochemical signals' cascade transcripted into biophysical processes and viceversa. The process is complex in nature, ...
- Dynamic shear-influenced collagen self-assembly
[作者:Saeidi, N; Sander, EA; Ruberti, JW,期刊:BIOMATERIALS, 页码:6581-6592 , 文章类型: Article,,卷期:2009年30-34]
- The ability to influence the direction of polymerization of a self-assembling biomolecular system has the potential to generate materials with extremely high anisotropy. In biological systems where highly-oriented cellul...
- Distinctive regulation of contact activation by antithrombin and C1-inhibitor on activated platelets and material surfaces
[作者:Back, J; Lang, MH; Elgue, G; Kalbitz, M; Sanchez, J; Ekdahl, KN; Nilsson, B,期刊:BIOMATERIALS, 页码:6573-6580 , 文章类型: Article,,卷期:2009年30-34]
- Activated human plate lets trigger FXII-mediated contact activation, which leads to the generation of FXIla-antithrombin (AT) and FXIa-AT complexes. This suggests that contact activation takes place at different sites, o...
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