- Are the effects of alpha-glucosidase inhibitors on cardiovascular events related to elevated levels of hydrogen gas in the gastrointestinal tract?
[作者:Suzuki, Y; Sano, M; Hayashida, K; Ohsawa, I; Ohta, S; Fukuda, K,期刊:FEBS Letters, 页码:2157-2159 , 文章类型: Article,,卷期:2009年583-13]
- The major side-effect of treatment with alpha-glucosidase inhibitors, flatulence, occurs when undigested carbohydrates are fermented by colonic bacteria, resulting in gas formation. We propose that the cardiovascular ben...
- Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1
[作者:Jiang, M; Gao, YK; Yang, T; Zhu, XL; Chen, JY,期刊:FEBS Letters, 页码:2171-2178 , 文章类型: Article,,卷期:2009年583-13]
- A novel cyclin, CCNY, was identified as a PFTK1 interacting protein in a yeast two-hybrid screen. The cyclin box in CCNY and the PFTAIRE motif in PFTK1 are both required for the interaction which was confirmed by in vivo...
- Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains
[作者:Sasaki, K; Shimura, H; Itaya, M; Tanaka, R; Mori, H; Mizuno, Y; Kosik, KS; Tanaka, S; Hattori, N,期刊:FEBS Letters, 页码:2194-2200 , 文章类型: Article,,卷期:2009年583-13]
- Phosphorylated tau (p-tau) is the principal component of neurofibrillary tangles, a pathological hallmark, and likely plays a neurotoxic role in tauopathies including Alzheimer's disease (AD), progressive supranuclear pa...
- A selective small-molecule inhibitor of c-Jun N-terminal kinase 1
[作者:Yao, K; Cho, YY; Bode, AM; Vummenthala, A; Park, JG; Liu, KD; Pang, YP; Dong, ZG,期刊:FEBS Letters, 页码:2208-2212 , 文章类型: Article,,卷期:2009年583-13]
- Indiscriminately suppressing total c-Jun N-terminal kinase (JNK) activity is not an appropriate strategy because each JNK appears to have a distinct function in cancer, asthma, diabetes, or Parkinson's disease. Herein, w...
- Dexamethasone regulates expression of BRUCE/Apollon and the proliferation of neural progenitor cells
[作者:Sippel, M; Rajala, R; Korhonen, L; Bornhauser, B; Sokka, AL; Naito, M; Lindholm, D,期刊:FEBS Letters, 页码:2213-2217 , 文章类型: Article,,卷期:2009年583-13]
- Glucocorticoid hormones (GHs) regulate cell proliferation of neural progenitor cells (NPCs) contributing to reduction of neurogenesis after stress. We show here that dexamethasone (Dex) decreases BRUCE/Apollon (BRUCE) in...
- Molecular characterization and kinetic properties of a novel two-domain taurocyamine kinase from the lung fluke Paragonimus westermani
[作者:Jarilla, BR; Tokuhiro, S; Nagataki, M; Hong, SJ; Uda, K; Suzuki, T; Agatsuma, T,期刊:FEBS Letters, 页码:2218-2224 , 文章类型: Article,,卷期:2009年583-13]
- Taurocyamine kinase (TK) was previously reported to be restricted to certain marine annelids; however, the present study has proven otherwise. The lung fluke Paragonimus westermani has a contiguous two-domain TK with a m...
- Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells
[作者:Yoshida, M; Dezaki, K; Yamato, S; Aoki, A; Sugawara, H; Toyoshima, H; Ishikawa, S; Masanobu, K; Masanori, NB; Yada, T; Kakei, M,期刊:FEBS Letters, 页码:2225-2230 , 文章类型: Article,,卷期:2009年583-13]
- Regulation of delayed rectifier-type K+ channels (Kv-channels) by glucose was studied in rat pancreatic beta-cells. The Kv-channel current was increased in amplitudes by increasing glucose concentration from 2.8 to 16.6 ...
- Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion
[作者:Zick, M; Duvezin-Caubet, S; Schafer, A; Vogel, F; Neupert, W; Reichert, AS,期刊:FEBS Letters, 页码:2237-2243 , 文章类型: Article,,卷期:2009年583-13]
- The mitochondrial dynamin-like GTPase Mgm1 exists as a long (l-Mgm1) and a short isoform (s-Mgm1). They both are essential for mitochondrial fusion. Here we show that the isoforms interact in a homotypic and heterotypic ...
- Heme-dependent autophosphorylation of a heme sensor kinase, ChrS, from Corynebacterium diphtheriae reconstituted in proteoliposomes
[作者:Ito, Y; Nakagawa, S; Komagata, A; Ikeda-Saito, M; Shiro, Y; Nakamura, H,期刊:FEBS Letters, 页码:2244-2248 , 文章类型: Article,,卷期:2009年583-13]
- Corynebacterium diphteriae employs the response regulator, ChrA, and the sensor kinase, ChrS, of a two-component signal transduction system to utilize host heme iron. Although ChrS is predicted to encode a heme sensor, t...
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