- Rapid down-regulation of mitochondrial fat metabolism in human muscle after training cessation is dissociated from changes in insulin sensitivity
[作者:Rimbert, V; Vidal, H; Duche, P; Debard, C; Giraudet, C; Boirie, Y; Chardigny, JM; Morio, B,期刊:FEBS Letters, 页码:2927-2933 , 文章类型: Article,,卷期:2009年583-17]
- The association between impairment in mitochondrial muscle fat oxidative capacity (OXFA) and occurrence of insulin resistance was examined in 14 healthy trained men (age, 24 +/- 4 yr) submitted to 4 weeks of training ces...
- A third functional isoform enriched in mushroom body neurons is encoded by the Drosophila 14-3-3 zeta gene
[作者:Messaritou, G; Leptourgidou, F; Franco, M; Skoulakis, EMC,期刊:FEBS Letters, 页码:2934-2938 , 文章类型: Article,,卷期:2009年583-17]
- 14-3-3 Proteins are highly conserved across eukaryotes, typically encoded by multiple genes in most species. Drosophila has only two such genes, 14-3-3 zeta (leo), encoding two isoforms LEOI and LEOII, and 14-3-3 epsilon...
- Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme
[作者:Gajiwala, KS; Margosiak, S; Lu, J; Cortez, J; Su, Y; Nie, Z; Appelt, K,期刊:FEBS Letters, 页码:2939-2946 , 文章类型: Article,,卷期:2009年583-17]
FabH (beta-ketoacyl-acyl carrier protein synthase III) is unique in that it initiates fatty acid biosynthesis, is inhibited by long-chain fatty acids providing means for feedback control of the process, and dictates t...
- The preadipocyte factor DLK1 marks adult mouse adipose tissue residing vascular cells that lack in vitro adipogenic differentiation potential
[作者:Andersen, DC; Jensen, L; Schroder, HD; Jensen, CH,期刊:FEBS Letters, 页码:2947-2953 , 文章类型: Article,,卷期:2009年583-17]
- Delta-like 1 (Dlk1) is expressed in 3T3-L1 preadipocytes and has frequently been referred to as "the" preadipocyte marker, yet the phenotype of DLK1(+) cells in adipose tissue remains undetermined. Herein, we demonstrate...
- Similar distribution of simple sequence repeats in diverse completed Human Immunodeficiency Virus Type 1 genomes
[作者:Chen, M; Tan, ZY; Jiang, JH; Li, MF; Chen, HJ; Shen, GL; Yu, RQ,期刊:FEBS Letters, 页码:2959-2963 , 文章类型: Article,,卷期:2009年583-17]
- The survey of simple sequence repeats (SSRs) has been extensively made in eukaryotes and prokaryotes. However, its still rare in viruses. Thus, we undertook a survey of SSRs in Human Immunodeficiency Virus Type 1 (HIV-1)...
- Silencing of TNF-alpha receptors coordinately suppresses TNF-alpha expression through NF-kappa B activation blockade in THP-1 macrophage
[作者:Verma, N; Chaudhury, I; Kumar, D; Das, RH,期刊:FEBS Letters, 页码:2968-2974 , 文章类型: Article,,卷期:2009年583-17]
- Persistently elevated level of TNF-alpha has been implicated in several inflammatory disorders, however, its autocrine production through TNF-alpha receptors signaling is poorly understood. Here we report that simultaneo...
- The COPI system: Molecular mechanisms and function
[作者:Beck, R; Ravet, M; Wieland, FT; Cassel, D,期刊:FEBS Letters, 页码:2701-2709 , 文章类型: Review,,卷期:2009年583-17]
- Transport of membranes and proteins in eukaryotic cells is mediated by vesicular carriers. Here we review the biogenesis and functions of COPI vesicles, carriers that operate in the early secretory pathway. We focus on m...
- Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma
[作者:Kim, K; Kim, KH; Ha, E; Park, JY; Sakamoto, N; Cheong, J,期刊:FEBS Letters, 页码:2720-2726 , 文章类型: Article,,卷期:2009年583-17]
- Steatosis is an established risk factor for disease progression in cases of chronic hepatitis C. Recently it was demonstrated that Hepatitis C virus (HCV) core and non-structural (NS)2 proteins (NS2) induce lipid accumul...
- Binding of divalent cations is essential for the activity of the organellar peptidasome in Arabidopsis thaliana, AtPreP
[作者:Backman, HG; Pessoa, J; Eneqvist, T; Glaser, E,期刊:FEBS Letters, 页码:2727-2733 , 文章类型: Article,,卷期:2009年583-17]
- The dual-targeted mitochondrial and chloroplastic zinc metallooligopeptidase from Arabidopsis, AtPreP, functions as a peptidasome that degrades targeting peptides and other small unstructured peptides. In addition to Zn ...
- A cold-induced thioredoxin h of rice, OsTrx23, negatively regulates kinase activities of OsMPK3 and OsMPK6 in vitro
[作者:Xie, GS; Kato, H; Sasaki, K; Imai, R,期刊:FEBS Letters, 页码:2734-2738 , 文章类型: Article,,卷期:2009年583-17]
- Cytosolic thioredoxins are small conserved proteins that are involved in cellular redox regulation. Here, we report that a major and cold-induced thioredoxin h of rice, OsTrx23, has an inhibitory activity on stress-activ...
- Inhibition of human initiator caspase 8 and effector caspase 3 by cross-class inhibitory bovSERPINA3-1 and A3-3
[作者:Herrera-Mendez, CH; Becila, S; Blanchet, X; Pelissier, P; Delourme, D; Coulis, G; Sentandreu, MA; Boudjellal, A; Bremaud, L; Ouali, A,期刊:FEBS Letters, 页码:2743-2748 , 文章类型: Article,,卷期:2009年583-17]
- Serpins are a superfamily of structurally conserved proteins. Inhibitory serpins use a suicide substrate-like mechanism. Some are able to inhibit cysteine proteases in cross-class inhibition. Here, we demonstrate for the...
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