- Thermodynamic analysis of substrate induced domain closure of 3-phosphoglycerate kinase
[作者:Varga, A; Szabo, J; Flachner, B; Gugolya, Z; Vonderviszt, F; Zavodszky, P; Vas, M,期刊:FEBS Letters, 页码:3660-3664 , 文章类型: Article,,卷期:2009年583-22]
- The energetic changes accompanying domain closure of 3-phosphoglycerate kinase, a typical hinge-bending enzyme, were assessed. Calorimetric titrations of the enzyme with each substrate, both in the absence and presence o...
- The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro
[作者:Kim, JI; Surewicz, K; Gambetti, P; Surewicz, WK,期刊:FEBS Letters, 页码:3671-3675 , 文章类型: Article,,卷期:2009年583-22]
- Transmissible spongiform encephalopathies are associated with an autocatalytic conversion of normal prion protein, PrPC, to a protease-resistant form, PrPres. This autocatalytic reaction can be reproduced in vitro using ...
- The retinal structure of channelrhodopsin-2 assessed by resonance Raman spectroscopy
[作者:Nack, M; Radu, I; Bamann, C; Bamberg, E; Heberle, J,期刊:FEBS Letters, 页码:3676-3680 , 文章类型: Article,,卷期:2009年583-22]
- Channelrhodopsin-2 mediates phototaxis in green algae by acting as a light-gated cation channel. As a result of this property, it is used as a novel optogenetic tool in neurophysiological applications. Structural informa...
- A conserved sequence in caveolin-1 is both necessary and sufficient for caveolin polarity and cell directional migration
[作者:Sun, XH; Liu, ZY; Chen, H; Beardsley, AR; Qi, Q; Liu, J,期刊:FEBS Letters, 页码:3681-3689 , 文章类型: Article,,卷期:2009年583-22]
- Caveolin-1 (Cav-1) plays an important role in the organization of signaling molecules involved in a variety of signaling pathways, including those mediating cell motility. Here we show that amino acids K47-K57 of Cav-1 a...
- Diffusion of a membrane protein, Tat subunit Hcf106, is highly restricted within the chloroplast thylakoid network
[作者:Vladimirou, E; Li, M; Aldridge, CP; Frigerio, L; Kirkilionis, M; Robinson, C,期刊:FEBS Letters, 页码:3690-3696 , 文章类型: Article,,卷期:2009年583-22]
- The thylakoid membrane forms stacked thylakoids interconnected by 'stromal' lamellae. Little is known about the mobility of proteins within this system. We studied a stromal lamellae protein, Hcf106, by targeting an Hcf1...
- Two types of cis-acting elements control the abaxial epidermis-specific transcription of the MIR165a and MIR166a genes
[作者:Yao, XZ; Wang, H; Li, H; Yuan, ZH; Li, FP; Yang, L; Huang, H,期刊:FEBS Letters, 页码:3711-3717 , 文章类型: Article,,卷期:2009年583-22]
- During leaf development, polarity formation is critical for leaf morphogenesis and functions. This process is regulated by several components including two microRNAs, miR165 and 166, which negatively regulate transcripti...
- Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytes
[作者:Weber, M; Sporrer, D; Weigert, J; Wanninger, J; Neumeier, M; Wurm, S; Stogbauer, F; Kopp, A; Bala, M; Schaffler, A; Buechler, C,期刊:FEBS Letters, 页码:3718-3724 , 文章类型: Article,,卷期:2009年583-22]
- Galectin-3 plays a role in atherosclerotic diseases, and the effect of adiponectin that protects from atherosclerotic diseases on monocytic galectin-3 was analysed. Adiponectin reduced galectin-3 mRNA, its cellular and s...
- MicroRNA 125a and its regulation of the p53 tumor suppressor gene
[作者:Zhang, YJ; Gao, JS; Tang, XL; Tucker, LD; Quesenberry, P; Rigoutsos, I; Ramratnam, B,期刊:FEBS Letters, 页码:3725-3730 , 文章类型: Article,,卷期:2009年583-22]
- MicroRNA (miRNA) are a class of non-coding RNA that suppress gene expression by degradation or translational inhibition of target RNA. Several miRNA have been shown to target oncogenes and recently miRNA-125b was shown t...
- Polo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnover
[作者:Dias, SS; Hogan, C; Ochocka, AM; Meek, DW,期刊:FEBS Letters, 页码:3543-3548 , 文章类型: Article,,卷期:2009年583-22]
- The E3 ubiqutin ligase, murne double-minute clone 2 (MDM2), promotes the degradation of p53 under normal homeostatic conditions. Several serine residues within the acidic domain of MDM2 are phosphorylated to maintain its...
- Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX
[作者:Hulikova, A; Zatovicova, M; Svastova, E; Ditte, P; Brasseur, R; Kettmann, R; Supuran, CT; Kopacek, J; Pastorek, J; Pastorekova, S,期刊:FEBS Letters, 页码:3563-3568 , 文章类型: Article,,卷期:2009年583-22]
- Carbonic anhydrase IX (CA IX) is a tumor-associated, hypoxia-induced enzyme involved in pH regulation and cell adhesion. Its catalytically active ectodomain (ECD) is linked to a transmembrane region and a short intracell...
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