- The mitochondrial permeability transition from yeast to mammals
[作者:Azzolin, L; von Stockum, S; Basso, E; Petronilli, V; Forte, MA; Bernardi, P,期刊:FEBS Letters, 页码:2504-2509 , 文章类型: Review,,卷期:2010年584-12]
- Regulated permeability changes have been detected in mitochondria across species. We review here their key features, with the goal of assessing whether a "permeability transition" similar to that observed in higher eukar...
- Tricks of the trade used to accelerate high-resolution structure determination of membrane proteins
[作者:Sonoda, Y; Cameron, A; Newstead, S; Omote, H; Moriyama, Y; Kasahara, M; Iwata, S; Drew, D,期刊:FEBS Letters, 页码:2539-2547 , 文章类型: Review,,卷期:2010年584-12]
- The rate at which X-ray structures of membrane proteins are solved is on a par with that of soluble proteins in the late 1970s. There are still many obstacles facing the membrane protein structural community. Recently, t...
- Molecular basis of cholera blood-group dependence and implications for a world characterized by climate change
[作者:Holmner, A; Mackenzie, A; Krengel, U,期刊:FEBS Letters, 页码:2548-2555 , 文章类型: Review,,卷期:2010年584-12]
- Climate change has the potential to increase the threat of water-borne diseases, through rises in temperature and sea-level, and precipitation variability. Cholera poses a particular threat, and the need to develop bette...
- Use of genome-scale metabolic models for understanding microbial physiology
[作者:Liu, LM; Agren, R; Bordel, S; Nielsen, J,期刊:FEBS Letters, 页码:2556-2564 , 文章类型: Review,,卷期:2010年584-12]
- The exploitation of microorganisms in industrial, medical, food and environmental biotechnology requires a comprehensive understanding of their physiology. The availability of genome sequences and accumulation of high-th...
- The pre-B cell receptor checkpoint
[作者:Martensson, IL; Almqvist, N; Grimsholm, O; Bernardi, AI,期刊:FEBS Letters, 页码:2572-2579 , 文章类型: Review,,卷期:2010年584-12]
- B lymphocytes are essential antibody-producing cells of the immune system. During the development of progenitor B cells to mature B cells that express a membrane-bound antibody, the B cell receptor (BCR), the cells under...
- Structural insights into eukaryotic aquaporin regulation
[作者:Tornroth-Horsefield, S; Hedfalk, K; Fischer, G; Lindkvist-Petersson, K; Neutze, R,期刊:FEBS Letters, 页码:2580-2588 , 文章类型: Review,,卷期:2010年584-12]
- Aquaporin-mediated water transport across cellular membranes is an ancient, ubiquitous mechanism within cell biology. This family of integral membrane proteins includes both water selective pores (aquaporins) and transpo...
- Phosphorylation of the Na+,K+-ATPase and the H+,K+-ATPase
[作者:Poulsen, H; Morth, P; Egebjerg, J; Nissen, P,期刊:FEBS Letters, 页码:2589-2595 , 文章类型: Review,,卷期:2010年584-12]
- Phosphorylation is a widely used, reversible means of regulating enzymatic activity. Among the important phosphorylation targets are the Na+,K+- and H+,K+-ATPases that pump ions against their chemical gradients to uphold...
- A structural classification of substrate-binding proteins
[作者:Berntsson, RPA; Smits, SHJ; Schmitt, L; Slotboom, DJ; Poolman, B,期刊:FEBS Letters, 页码:2606-2617 , 文章类型: Review,,卷期:2010年584-12]
- Substrate-binding proteins (SBP) are associated with a wide variety of protein complexes. The proteins are part of ATP-binding cassette transporters for substrate uptake, ion gradient driven transporters, DNA-binding pro...
- Circadian clock control of the cellular response to DNA damage
[作者:Sancar, A; Lindsey-Boltz, LA; Kang, TH; Reardon, JT; Lee, JH; Ozturk, N,期刊:FEBS Letters, 页码:2618-2625 , 文章类型: Review,,卷期:2010年584-12]
- Mammalian cells possess a cell-autonomous molecular clock which controls the timing of many biochemical reactions and hence the cellular response to environmental stimuli including genotoxic stress. The clock consists of...
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