- 50 Years of Protein Structure Analysis
[作者:Strandberg, B; Dickerson, RE; Rossmann, MG,期刊:Journal of Molecular Biology, 页码:2-32 , 文章类型: Article,,卷期:2009年392-1]
- Fifty years ago, Max Perutz and John Kendrew at Cambridge University achieved something that many people at the time considered impossible: they were the first to use x-ray crystallography to decipher the molecular struc...
- Effects of Chloride Ion Binding on the Photochemical Properties of Salinibacter Sensory Rhodopsin I
[作者:Suzuki, D; Furutan, Y; Inoue, K; Kikukawa, T; Sakai, M; Fujii, M; Kandori, H; Homma, M; Sudo, Y,期刊:Journal of Molecular Biology, 页码:48-62 , 文章类型: Article,,卷期:2009年392-1]
- Microbial organisms utilize light not only as energy sources but also as signals by which rhodopsins (containing retinal as a chromophore) work as photoreceptors. Sensory rhodopsin I (SRI) is a dual photoreceptor that re...
- Energetics of MazG Unfolding in Correlation with Its Structural Features
[作者:Drobnak, I; Korencic, A; Loris, R; Marianovsky, I; Glaser, G; Jamnik, A; Vesnaver, G; Lah, J,期刊:Journal of Molecular Biology, 页码:63-74 , 文章类型: Article,,卷期:2009年392-1]
- MazG is a homodimeric a-helical protein that belongs to the superfamily of all-alpha NTP pyrophosphatases. Its function has been connected to the regulation of the toxin-antitoxin module mazEF, implicated in programmed g...
- Molecular Cloning and Crystal Structural Analysis of a Novel beta-N-Acetylhexosaminidase from Paenibacillus sp TS12 Capable of Degrading Glycosphingolipids
[作者:Sumida, T; Ishii, R; Yanagisawa, T; Yokoyama, S; Ito, M,期刊:Journal of Molecular Biology, 页码:87-99 , 文章类型: Article,,卷期:2009年392-1]
- We report the molecular cloning and characterization of two novel beta-N-acetylhexosaminidases (beta-HEX, EC 3.2.1.52) from Paenibacillus sp. strain TS12. The two beta-HEXs (Hex1 and Hex2) were 70% identical in primary s...
- NMR Structure of the N-Terminal Domain of Capsid Protein from the Mason-Pfizer Monkey Virus
[作者:Macek, P; Chmelik, J; Krizova, I; Kaderavek, P; Padrta, P; Zidek, L; Wildova, M; Hadravova, R; Chaloupkova, R; Pichova, I; Ruml, T; Rumlova, M; Sklenar, V,期刊:Journal of Molecular Biology, 页码:100-114 , 文章类型: Article,,卷期:2009年392-1]
- The high-resolution structure of the N-terminal domain (NTD) of the retroviral capsid protein (CA) of Mason-Pfizer monkey virus (M-PMV), a member of the betaretrovirus family, has been determined by NMR. The MPMV NTD CA ...
- Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2
[作者:Conlan, AR; Axelrod, HL; Cohen, AE; Abresch, EC; Zuris, J; Yee, D; Nechushtai, R; Jennings, PA; Paddock, ML,期刊:Journal of Molecular Biology, 页码:143-153 , 文章类型: Article,,卷期:2009年392-1]
The endoplasmic reticulum protein Miner1 is essential for health and longevity. Mis-splicing of CISD2, which codes for Miner1, is causative in Wolfram Syndrome 2 (WFS2) resulting in early onset optic atrophy, diabetes...
- Structural Insights into the Protease-like Antigen Plasmodium falciparum SERA5 and Its Noncanonical Active-Site Serine
[作者:Hodder, AN; Malby, RL; Clarke, OB; Fairlie, WD; Colman, PM; Crabb, BS; Smith, BJ,期刊:Journal of Molecular Biology, 页码:154-165 , 文章类型: Article,,卷期:2009年392-1]
- The sera genes of the malaria-causing parasite Plasmodium encode a family of unique proteins that are maximally expressed at the time of egress of parasites from infected red blood cells. These multi-domain proteins are ...
- Refinement of Protein Structures into Low-Resolution Density Maps Using Rosetta
[作者:DiMaio, F; Tyka, MD; Baker, ML; Chiu, W; Baker, D,期刊:Journal of Molecular Biology, 页码:181-190 , 文章类型: Article,,卷期:2009年392-1]
- We describe a method based on Rosetta structure refinement for generating high-resolution, all-atom protein models from electron cryomicroscopy density maps. A local measure of the fit of a model to the density is used t...
- Peptide NMHRYPNQ of the Cellular Prion Protein (PrPC) Inhibits Aggregation and Is a Potential Key for Understanding Prion-Prion Interactions
[作者:Rehders, D; Claasen, B; Redecke, L; Buschke, A; Reibe, C; Jehmlich, N; von Bergen, M; Betzel, C; Meyer, B,期刊:Journal of Molecular Biology, 页码:198-207 , 文章类型: Article,,卷期:2009年392-1]
- Pathogenesis of transmissible spongiform. encephalopathies is correlated with a conversion of the normal cellular form of the prion protein (PrPC) into the abnormal isoform (scrapie form of PrP). Contact of the normal Pr...
- Prokaryotic Ubiquitin-Like Protein Pup Is Intrinsically Disordered
[作者:Chen, X; Solomon, WC; Kang, Y; Cerda-Maira, F; Darwin, KH; Walters, KJ,期刊:Journal of Molecular Biology, 页码:208-217 , 文章类型: Article,,卷期:2009年392-1]
- The prokaryotic ubiquitin-like protein Pup targets substrates for degradation by the Mycobacterium tuberculosis proteasome through its interaction with Mpa, an ATPase that is thought to abut the 20S catalytic subunit. Ub...
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