- Lattice Structure of Cytoplasmic Microtubules in a Cultured Mammalian Cell
[作者:McIntosh, JR; Morphew, MK; Grissom, PM; Gilbert, SP; Hoenger, A,期刊:Journal of Molecular Biology, 页码:177-182 , 文章类型: Article,,卷期:2009年394-2]
- Tubulin can polymerize in two distinct arrangements: "B-lattices," in which the alpha-tubulins of one protofilament lie next to alpha-tubulins in the neighboring protofilaments, or the "A" configuration, where alpha-tubu...
- RelB and RelE of Escherichia coli Form a Tight Complex That Represses Transcription via the Ribbon-Helix-Helix Motif in RelB
[作者:Overgaard, M; Borch, J; Gerdes, K,期刊:Journal of Molecular Biology, 页码:183-196 , 文章类型: Article,,卷期:2009年394-2]
- RelB, the ribbon-helix-helix (RHH) repressor encoded by the relBE toxin-antitoxin locus of Escherichia coli, interacts with RelE and thereby counteracts the mRNA cleavage activity of RelE. In addition, RelB dimers repres...
- The Higher Structure of Chromatin in the LCR of the beta-Globin Locus Changes during Development
[作者:Fang, XD; Yin, WX; Xiang, P; Han, HM; Stamatoyannopoulos, G; Li, QL,期刊:Journal of Molecular Biology, 页码:197-208 , 文章类型: Article,,卷期:2009年394-2]
- The beta-globin locus control region (LCR) is able to enhance the expression of all globin genes throughout the course of development. However, the chromatin structure of the LCR at the different developmental stages is ...
- Binding to PCNA in Euryarchaeal DNA Replication Requires Two PIP Motifs for DNA Polymerase D and One PIP Motif for DNA Polymerase B
[作者:Castrec, B; Rouillon, C; Henneke, G; Flament, D; Querellou, J; Raffin, JP,期刊:Journal of Molecular Biology, 页码:209-218 , 文章类型: Article,,卷期:2009年394-2]
- Replicative DNA polymerases possess a canonical C-terminal proliferating cell nuclear antigen (PCNA)-binding motif termed the PCNA-interacting protein (PIP) box. We investigated the role of the PIP box on the functional ...
- Relationship between Protein Stabilization and Protein Rigidification Induced by Mannosylglycerate
[作者:Pais, TM; Lamosa, P; Garcia-Moreno, B; Turner, DL; Santos, H,期刊:Journal of Molecular Biology, 页码:237-250 , 文章类型: Article,,卷期:2009年394-2]
- Understanding protein stabilization by small organic compounds is a topic of great practical importance. The effect of mannosylglycerate, a charged compatible solute typical of thermophilic microorganisms, on a variant o...
- eIF1 Controls Multiple Steps in Start Codon Recognition during Eukaryotic Translation Initiation
[作者:Nanda, JS; Cheung, YN; Takacs, JE; Martin-Marcos, P; Saini, AK; Hinnebusch, AG; Lorsch, JR,期刊:Journal of Molecular Biology, 页码:268-285 , 文章类型: Article,,卷期:2009年394-2]
- Eukaryotic translation initiation factor (eIF) 1 is a central mediator of start codon recognition. Dissociation of eIF1 from the preinitiation complex (PIC) allows release of phosphate from the G-protein factor eIF2, tri...
- Two Complementary Enzymes for Threonylation of tRNA in Crenarchaeota: Crystal Structure of Aeropyrum pernix Threonyl-tRNA Synthetase Lacking a cis-Editing Domain
[作者:Shimizu, S; Juan, ECM; Sato, Y; Miyashita, Y; Hoque, MM; Suzuki, K; Sagara, T; Tsunoda, M; Sekiguchi, T; Dock-Bregeon, AC; Moras, D; Takenaka, A,期刊:Journal of Molecular Biology, 页码:286-296 , 文章类型: Article,,卷期:2009年394-2]
In protein synthesis, threonyl-tRNA synthetase (ThrRS) must recognize threonine (Thr) from the 20 kinds of amino acids and the cognate tRNA(Thr), from different tRNAs in order to generate Thr-tRNA(Thr). In general, an...
- Reconstitution and Engineering of Apoptotic Protein Interactions on the Bacterial Cell Surface
[作者:Sun, JJ; Abdeljabbar, DM; Clarke, N; Bellows, ML; Floudas, CA; Link, AJ,期刊:Journal of Molecular Biology, 页码:297-305 , 文章类型: Article,,卷期:2009年394-2]
- The interactions between pro- and anti-apoptotic members of the Bcl-2 class of proteins control whether a cell lives or dies, and the study of these protein-protein interactions has been an area of intense research. In t...
- Identification of the Interactions Critical for Propeptide-Catalyzed Folding of Tk-Subtilisin
[作者:Tanaka, S; Matsumura, H; Koga, Y; Takano, K; Kanaya, S,期刊:Journal of Molecular Biology, 页码:306-319 , 文章类型: Article,,卷期:2009年394-2]
- Tk-subtilisin requires Ca2+, for folding. This folding is accelerated by the chaperone function of its propeptide (Tkpro). Several Tkpro and Tk-subtilisin derivatives were constructed to examine whether the interactions ...
- The 20S Proteasome as an Assembly Platform for the 19S Regulatory Complex
[作者:Hendil, KB; Kriegenburg, F; Tanaka, K; Murata, S; Lauridsen, AMB; Johnsen, AH; Hartmann-Petersen, R,期刊:Journal of Molecular Biology, 页码:320-328 , 文章类型: Article,,卷期:2009年394-2]
- 26S proteasomes consist of cylindrical 20S proteasomes with 19S regulatory complexes attached to the ends. Treatment with high concentrations of salt causes the regulatory complexes to separate into two sub-complexes, th...
|