- Anti-integrin monoclonal antibodies
[作者:Byron, A; Humphries, JD; Askari, JA; Craig, SE; Mould, AP; Humphries, MJ,期刊:Journal of cell science, 页码:4009-4011 , 文章类型: Article,,卷期:2009年122-22]
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- KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules
[作者:Nachat, R; Cipolat, S; Sevilla, LM; Chhatriwala, M; Groot, KR; Watt, FM,期刊:Journal of cell science, 页码:4035-4041 , 文章类型: Article,,卷期:2009年122-22]
- Kazrin is a widely expressed, evolutionarily conserved cytoplasmic protein that binds the cytolinker protein periplakin. Multiple functions of kazrin have been reported, including regulation of desmosome assembly, embryo...
- Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180
[作者:Messaritou, G; East, L; Roghi, C; Isacke, CM; Yarwood, H,期刊:Journal of cell science, 页码:4042-4048 , 文章类型: Article,,卷期:2009年122-22]
- The molecular interactions leading to organised, controlled extracellular matrix degradation are of central importance during growth, development and tissue repair, and when deregulated contribute to disease processes in...
- Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases
[作者:Gu, DM; Sater, AK; Ji, H; Cho, K; Clark, M; Stratton, SA; Barton, MC; Lu, Q; McCrea, PD,期刊:Journal of cell science, 页码:4049-4061 , 文章类型: Article,,卷期:2009年122-22]
- Catenins of the p120 subclass display an array of intracellular localizations and functions. Although the genetic knockout of mouse delta-catenin results in mild cognitive dysfunction, we found severe effects of its depl...
- Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway
[作者:Kang, YS; Zhao, XH; Lovaas, J; Eisenberg, E; Greene, LE,期刊:Journal of cell science, 页码:4062-4069 , 文章类型: Article,,卷期:2009年122-22]
- To understand the role of clathrin-mediated endocytosis in the internalization of normal cellular prion protein (PrPc) in neuronal cells, N2a cells were depleted of clathrin by RNA interference. PrPc internalization via ...
- Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress
[作者:Vassin, VM; Anantha, RW; Sokolova, E; Kanner, S; Borowiec, JA,期刊:Journal of cell science, 页码:4070-4080 , 文章类型: Article,,卷期:2009年122-22]
- ATR is an essential kinase activated in response to DNA-replication stress, with a known target being the RPA2 subunit of human replication protein A (RPA). We find that S33-RPA2 phosphorylation by ATR occurs primarily i...
- HSCARG inhibits activation of NF-kappa B by interacting with I kappa B kinase-beta
[作者:Gan, QN; Li, TT; Hu, B; Lian, M; Zheng, XF,期刊:Journal of cell science, 页码:4081-4088 , 文章类型: Article,,卷期:2009年122-22]
- HSCARG is a recently identified human NADPH sensor. Our previous studies have shown that HSCARG can affect NO production and cell viability, but the signal pathway mediated by this protein is unknown. Here, we show that ...
- VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion
[作者:Kean, MJ; Williams, KC; Skalski, M; Myers, D; Burtnik, A; Foster, D; Coppolino, MG,期刊:Journal of cell science, 页码:4089-4098 , 文章类型: Article,,卷期:2009年122-22]
- Cellular remodeling of the extracellular matrix (ECM), an essential component of many physiological and pathological processes, is dependent on the trafficking and secretion of matrix metalloproteinases (MMPs). Soluble N...
- Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins
[作者:Ostlund, C; Folker, ES; Choi, JC; Gomes, ER; Gundersen, GG; Worman, HJ,期刊:Journal of cell science, 页码:4099-4108 , 文章类型: Article,,卷期:2009年122-22]
- The linker of nucleoskeleton and cytoskeleton (LINC) complex is situated in the nuclear envelope and forms a connection between the lamina and cytoskeletal elements. Sun1, Sun2 and nesprin-2 are important components of t...
- Frequenin/NCS-1 and the Ca2+-channel alpha(1)-subunit co-regulate synaptic transmission and nerve-terminal growth
[作者:Dason, JS; Romero-Pozuelo, J; Marin, L; Iyengar, BG; Klose, MK; Ferrus, A; Atwood, HL,期刊:Journal of cell science, 页码:4109-4121 , 文章类型: Article,,卷期:2009年122-22]
- Drosophila Frequenin (Frq) and its mammalian and worm homologue, NCS-1, are Ca2+-binding proteins involved in neurotransmission. Using site-specific recombination in Drosophila, we created two deletions that removed the ...
- Reprogramming of Xist against the pluripotent state in fusion hybrids
[作者:Do, JT; Han, DW; Gentile, L; Sobek-Klocke, I; Wutz, A; Scholer, HR,期刊:Journal of cell science, 页码:4122-4129 , 文章类型: Article,,卷期:2009年122-22]
- The fusion of somatic cells with pluripotent cells results in the generation of pluripotent hybrid cells. Because the `memory' of somatic cells seems to be erased during fusion-induced reprogramming, genetic reprogrammin...
- Stat3 promotes directional cell migration by regulating Rac1 activity via its activator beta PIX
[作者:Teng, TS; Lin, BH; Manser, E; Ng, DCH; Cao, XM,期刊:Journal of cell science, 页码:4150-4159 , 文章类型: Article,,卷期:2009年122-22]
- Stat3 is a member of the signal transducer and activator of transcription family, which is important for cytokine signaling as well as for a number of cellular processes including cell proliferation, anti-apoptosis and i...
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