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  • A dual role for EDEM1 in the processing of rod opsin
    [作者:Kosmaoglou, M; Kanuga, N; Aguila, M; Garriga, P; Cheetham, ME,期刊:Journal of cell science, 页码:4465-4472 , 文章类型: Article,,卷期:2009年122-24]
  • Mutations in rod opsin, the archetypal G-protein-coupled receptor, cause retinitis pigmentosa. The majority of mutations, e.g. P23H, cause protein misfolding, resulting in ER retention, induction of the unfolded protein ...