- Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast
[作者:Meitinger, F; Petrova, B; Lombardi, IM; Bertazzi, DT; Hub, B; Zentgraf, H; Pereira, G,期刊:Journal of cell science, 页码:1851-1861 , 文章类型: Article,,卷期:2010年123-11]
- The mitotic-exit network (MEN) is a signaling pathway that is essential for the coordination of mitotic exit and cytokinesis. Whereas the role of the MEN in mitotic exit is well established, the molecular mechanisms by w...
- A mitotic kinesin-6, Pav-KLP, mediates interdependent cortical reorganization and spindle dynamics in Drosophila embryos
[作者:Sommi, P; Ananthakrishnan, R; Cheerambathur, DK; Kwon, M; Morales-Mulia, S; Brust-Mascher, I; Mogilner, A,期刊:Journal of cell science, 页码:1862-1872 , 文章类型: Article,,卷期:2010年123-11]
- We investigated the role of Pav-KLP, a kinesin-6, in the coordination of spindle and cortical dynamics during mitosis in Drosophila embryos. In vitro, Pav-KLP behaves as a dimer. In vivo, it localizes to mitotic spindles...
- Claudin-2, a component of the tight junction, forms a paracellular water channel
[作者:Rosenthal, R; Milatz, S; Krug, SM; Oelrich, B; Schulzke, JD; Amasheh, S; Gunzel, D; Fromm, M,期刊:Journal of cell science, 页码:1913-1921 , 文章类型: Article,,卷期:2010年123-11]
- Whether or not significant amounts of water pass the tight junction (TJ) of leaky epithelia is still unresolved, because it is difficult to separate transcellular water flux from TJ-controlled paracellular water flux. Us...
- LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche
[作者:Gajera, CR; Emich, H; Lioubinski, O; Christ, A; Beckervordersandforth-Bonk, R; Yoshikawa, K; Bachmann, S; Christensen, EI; Gotz, M; Kempermann, G; Peterson, AS; Willnow, TE; Hammes, A,期刊:Journal of cell science, 页码:1922-1930 , 文章类型: Article,,卷期:2010年123-11]
- The microenvironment of growth factors in the subependymal zone (SEZ) of the adult brain provides the instructive milieu for neurogenesis to proceed in this germinal niche. In particular, tight regulation of bone morphog...
- Non-conducting function of the Kv2.1 channel enables it to recruit vesicles for release in neuroendocrine and nerve cells
[作者:Feinshreiber, L; Singer-Lahat, D; Friedrich, R; Matti, U; Sheinin, A; Yizhar, O; Nachman, R; Chikvashvili, D; Rettig, J; Ashery, U; Lotan, I,期刊:Journal of cell science, 页码:1940-1947 , 文章类型: Article,,卷期:2010年123-11]
- Regulation of exocytosis by voltage-gated K+ channels has classically been viewed as inhibition mediated by K+ fluxes. We recently identified a new role for Kv2.1 in facilitating vesicle release from neuroendocrine cells...
- Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway
[作者:Nethe, M; Anthony, EC; Fernandez-Borja, M; Dee, R; Geerts, D; Hensbergen, PJ; Deelder, AM; Schmidt, G; Hordijk, PL,期刊:Journal of cell science, 页码:1948-1958 , 文章类型: Article,,卷期:2010年123-11]
- Directional cell migration is crucially dependent on the spatiotemporal control of intracellular signalling events. These events regulate polarized actin dynamics, resulting in protrusion at the front of the cell and con...
- Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway
[作者:Lee, HS; Han, J; Lee, SH; Park, JA; Kim, KW,期刊:Journal of cell science, 页码:1959-1968 , 文章类型: Article,,卷期:2010年123-11]
- Meteorin is an orphan ligand which has been previously reported to control neuritogenesis and angiogenesis, as well as gliogenesis. However, the precise function of this factor in CNS development and the underlying molec...
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