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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共37条记录   Noninvasive Prediction of Fracture Risk in Patients with Metastatic Cancer to the Spine [作者：Snyder, BD; Cordio, MA; Nazarian, A; Kwak, SD; Chang, DJ; Entezari, V; Zurakowski, D; Parker, LM,期刊：Clinical Cancer Research, 页码：7676-7683 , 文章类型： Article，,卷期：2009年15-24] Purpose: Skeletal metastases affect up to 85% of breast cancer patients by the time of their death. This prospective in vivo study evaluated the diagnostic performance of computed tomography-based structural rigidity ana... miR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical Cancer [作者：Soon, PSH; Tacon, LJ; Gill, AJ; Bambach, CP; Sywak, MS; Campbell, PR; Yeh, MW; Wong, SG; Clifton-Bligh, RJ; Robinson, BG; Sidhu, SB,期刊：Clinical Cancer Research, 页码：7684-7692 , 文章类型： Article，,卷期：2009年15-24] Purpose: Adrenocortical adenomas are common, whereas adrenocortical carcinomas are rare. Discriminating between benign and malignant adrenocortical tumors using conventional histology can be difficult. In addition, adren... Barriers to Integrating Gene Profiling for Stage II Colon Cancer [作者：Kopetz, S; Abbruzzese, JL,期刊：Clinical Cancer Research, 页码：7451-7452 , 文章类型： Editorial Material，,卷期：2009年15-24] The identification of high-risk subsets of colon cancers has undergone extensive study over the years, and multidimensional gene signatures have shown promise for colon cancer. However, several hurdles need to be overcom... Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer [作者：Sparano, JA; Goldstein, LJ; Childs, BH; Shak, S; Brassard, D; Badve, S; Baehner, FL; Bugarini, R; Rowley, S; Perez, E; Shulman, LN; Martino, S; Davidson, NE; Sledge, GW; Gray, R,期刊：Clinical Cancer Research, 页码：7693-7700 , 文章类型： Article，,卷期：2009年15-24] Purpose: To perform an exploratory analysis of the relationship between gene expression and recurrence in operable hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-normal breast cancer pati... A Phase I Clinical Trial of CHT-25 a I-131-Labeled Chimeric Anti-CD25 Antibody Showing Efficacy in Patients with Refractory Lymphoma [作者：Dancey, G; Violet, J; Malaroda, A; Green, AJ; Sharma, SK; Francis, R; Othman, S; Parker, S; Buscombe, J; Griffin, N; Chan, PS; Malhotra, A; Woodward, N; Ramsay, A; Ross, P; Lister, TA; Amlot, P; Begent, R; McNamara, C,期刊：Clinical Cancer Research, 页码：7701-7710 , 文章类型： Article，,卷期：2009年15-24] Purpose: There is a need for new treatments for Hodgkin and T-cell lymphoma due to the development of drug resistance in a proportion of patients. This phase I study of radioimmunotherapy used CHT-25, a chimeric antibody... Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain Metastases [作者：Amaravadi, RK; Schuchter, LM; McDermott, DF; Kramer, A; Giles, L; Gramlich, K; Carberry, M; Troxel, AB; Letrero, R; Nathanson, KL; Atkins, MB; O'Dwyer, PJ; Flaherty, KT,期刊：Clinical Cancer Research, 页码：7711-7718 , 文章类型： Article，,卷期：2009年15-24] Purpose: The combination of the oral alkylating agent temozolomide and the oral multikinase inhibitor sorafenib was evaluated in advanced melanoma patients.Experimental Design: Patients with metastatic melanoma (n = 167)... Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck [作者：Nemunaitis, J; Clayman, G; Agarwala, SS; Hrushesky, W; Wells, JR; Moore, C; Hamm, J; Yoo, G; Baselga, J; Murphy, BA; Menander, KA; Licato, LL; Chada, S; Gibbons, RD; Olivier, M; Hainaut, P; Roth, JA; Sobol, RE; Goodwin, WJ,期刊：Clinical Cancer Research, 页码：7719-7725 , 文章类型： Article，,卷期：2009年15-24] Purpose: Most recurrent squamous cell carcinomas of the head and neck have a dysfunctional p53 tumor suppressor pathway contributing to treatment resistance. We hypothesized that tumor p53 biomarkers may predict the effi... Clinical Benefit of Allogeneic Melanoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients [作者：Toh, HC; Wang, WW; Chia, WK; Kvistborg, P; Sun, L; Teo, K; Phoon, YP; Soe, Y; Tan, SH; Hee, SW; Foo, KF; Ong, S; Koo, WH; Zocca, MB; Claesson, MH,期刊：Clinical Cancer Research, 页码：7726-7736 , 文章类型： Article，,卷期：2009年15-24] Purpose: We evaluated the clinical benefit of an allogeneic melanoma cell lysate (MCL)-pulsed autologous dendritic cell (DC) vaccine in advanced colorectal cancer patients expressing at least one of six MAGE-A antigens o... Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients [作者：Shi, CJ; Klein, AP; Goggins, M; Maitra, A; Canto, M; Ali, S; Schulick, R; Palmisano, E; Hruban, RH,期刊：Clinical Cancer Research, 页码：7737-7743 , 文章类型： Article，,卷期：2009年15-24] Purpose: Histologic findings in 51 pancreata resected from patients with a strong family history of pancreatic cancer were compared with the findings in 40 pancreata resected from patients with sporadic pancreatic cancer... High Innate Production Capacity of Proinflammatory Cytokines Increases Risk for Death from Cancer: Results of the PROSPER Study [作者：Trompet, S; de Craen, AJM; Mooijaart, S; Stott, DJ; Ford, I; Sattar, N; Jukema, W; Westendorp, RGJ,期刊：Clinical Cancer Research, 页码：7744-7748 , 文章类型： Article，,卷期：2009年15-24] Purpose: Various lines of evidence suggest that proinflammatory factors may play a role in tumor growth and metastasis, the leading cause of cancer-related mortality. However, most evidence originates from animal models,... Inhibition of Vascular Endothelial Growth Factor Receptor-1/Wnt/beta-catenin Crosstalk Leads to Tumor Cell Death [作者：Zeitlin, BD; Ellis, LM; Nor, JE,期刊：Clinical Cancer Research, 页码：7453-7455 , 文章类型： Editorial Material，,卷期：2009年15-24] Two genes are considered synthetic lethal if mutation of either alone allows cell viability, whereas simultaneous mutation leads to cell death. A synthetic lethal screen unveiled the dependency of Wnt/beta-catenin-addict... Cancer Drug Resistance Once Again: In the Era of Targeted Therapy [作者：Bates, SE,期刊：Clinical Cancer Research, 页码：7469-7470 , 文章类型： Editorial Material，,卷期：2009年15-24] Resistance to Trastuzumab in Breast Cancer [作者：Pohlmann, PR; Mayer, IA; Mernaugh, R,期刊：Clinical Cancer Research, 页码：7479-7491 , 文章类型： Review，,卷期：2009年15-24] HER2 is a transmembrane oncoprotein encoded by the HER2/neu gene and is overexpressed in approximately 20 to 25% of invasive breast cancers. It can be therapeutically targeted by trastuzumab, a humanized IgG1 kappa light... Differential Proteomics Identifies Protein Biomarkers That Predict Local Relapse of Head and Neck Squamous Cell Carcinomas [作者：Schaaij-Visser, TBM; Graveland, AP; Gauci, S; Braakhuis, BJM; Buijze, M; Heck, AJR; Kuik, DJ; Bloemena, E; Leemans, CR; Slijper, M; Brakenhoff, RH,期刊：Clinical Cancer Research, 页码：7666-7675 , 文章类型： Article，,卷期：2009年15-24] Purpose: The 5-year survival rates of head and neck squamous cell carcinomas (HNSCC) remain disappointing. HNSCCs develop in precursor fields of genetically altered cells that are often not completely resected when the t... Inhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides [作者：Slomiany, MG; Dai, L; Tolliver, LB; Grass, GD; Zeng, YP; Toole, BP,期刊：Clinical Cancer Research, 页码：7593-7601 , 文章类型： Article，,卷期：2009年15-24] Purpose: CD44 is one of the most common markers used for identification of highly tumorigenic subpopulations of human carcinoma cells, but little is known about the function of CD44 or its major ligand, hyaluronan, in th... Interactions between MDM2 and TP53 Genetic Alterations, and Their Impact on Response to MDM2 Inhibitors and Other Chemotherapeutic Drugs in Cancer Cells [作者：Liu, WQ; He, LJ; Ramirez, J; Ratain, MJ,期刊：Clinical Cancer Research, 页码：7602-7607 , 文章类型： Article，,卷期：2009年15-24] Purpose: MDM2 is a key negative regulator of the p53 signaling pathway. We aimed to evaluate the inter-relationships between MDM2 SNP309, mRNA expression, amplification, and TP53 mutations, as well as their correlations ...