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  • mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging
    [作者:Castilho, RM; Squarize, CH; Chodosh, LA; Williams, BO; Gutkind, JS,期刊:Cell Stem Cell, 页码:279-289 , 文章类型: Article,,卷期:2009年5-3]
  • Epidermal integrity is a complex process established during embryogenesis and maintained throughout the organism lifespan by epithelial stem cells. Although Wnt regulates normal epithelial stem cell renewal, aberrant Wnt...