- Lgr5(+ve) Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro
[作者:Barker, N; Huch, M; Kujala, P; van de Wetering, M; Snippert, HJ; van Es, JH; Sato, T; Stange, DE; Begthel, H; van den Born, M; Danenberg, E; van den Brink, S; Korving, J; Abo, A; Peters, PJ; Wright, N; Poulsom, R; Clevers, H,期刊:Cell Stem Cell, 页码:25-36 , 文章类型: Article,,卷期:2010年6-1]
- The study of gastric epithelial homeostasis and cancer has been hampered by the lack of stem cell markers and in vitro culture methods. The Writ target gene Lgr5 marks stem cells in the small intestine, colon, and hair f...
- An RNAi Screen Identifies TRRAP as a Regulator of Brain Tumor-Initiating Cell Differentiation
[作者:Wurdak, H; Zhu, ST; Romero, A; Lorger, M; Watson, J; Chiang, CY; Zhang, J; Natu, VS; Lairson, LL; Walker, JR; Trussell, CM; Harsh, GR; Vogels, H; Feld-Habermann, B; Orth, AP; Miraglia, LJ; Rines, DR; Skirboll, SL; Schultz, PG,期刊:Cell Stem Cell, 页码:37-47 , 文章类型: Article,,卷期:2010年6-1]
Glioblastoma multiforme (GBM) is a highly aggressive form of brain cancer associated with a very poor prognosis. Recently, the initiation and growth of GBM has been linked to brain tumor-initiating cells (BTICs), whic...
- Intermediate-Term Hematopoietic Stem Cells with Extended but Time-Limited Reconstitution Potential
[作者:Benveniste, P; Frelin, C; Janmohamed, S; Barbara, M; Herrington, R; Hyam, D; Iscove, NN,期刊:Cell Stem Cell, 页码:48-58 , 文章类型: Article,,卷期:2010年6-1]
- Sustained blood cell production depends on divisions by hematopoietic stem cells (HSCs) that yield both differentiating progeny as well as new HSCs via self-renewal. Differentiating progeny remain capable of self-renewal...
- Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells
[作者:Esteban, MA; Wang, T; Qin, BM; Yang, JY; Qin, DJ; Cai, JL; Li, W; Weng, ZH; Chen, JK; Ni, S; Chen, KS; Li, Y; Liu, XP; Xu, JY; Zhang, SQ; Li, F; He, WZ; Labuda, K; Song, YC; Peterbauer, A; Wolbank, S; Redl, H; Zhong, M; Cai, DZ; Zeng, LW; Pei, DQ,期刊:Cell Stem Cell, 页码:71-79 , 文章类型: Article,,卷期:2010年6-1]
- Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors. However, the low efficiency and slow kinetics of the reprogramming process have hampered progress with this technology. He...
- Cloning Mice and Men: Prohibiting the Use of iPS Cells for Human Reproductive Cloning
[作者:Lo, B; Parham, L; Alvarez-Buylla, A; Cedars, M; Conklin, B; Fisher, S; Gates, E; Giudice, L; Halme, DG; Hershon, W; Kriegstein, A; Kwok, PY; Wagner, R,期刊:Cell Stem Cell, 页码:16-20 , 文章类型: Editorial Material,,卷期:2010年6-1]
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