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  • An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
    [作者:van den Berg, DLC; Snoek, T; Mullin, NP; Yates, A; Bezstarosti, K; Demmers, J; Chambers, I; Poot, RA,期刊:Cell Stem Cell, 页码:369-381 , 文章类型: Article,,卷期:2010年6-4]
  • Transcription factors, such as Oct4, are critical for establishing and maintaining pluripotent cell identity. Whereas the genomic locations of several pluripotency transcription factors have been reported, the spectrum o...
  • Cell Competition: Pirates on the Tangled Bank
    [作者:Green, DR,期刊:Cell Stem Cell, 页码:287-288 , 文章类型: Editorial Material,,卷期:2010年6-4]
  • Competition by stem cells for occupation of a limited niche is a well-described phenomenon. Two recent studies highlight competition between hematopoietic stem cells based on p53. These findings have implications for bot...
  • Visualizing Blood Cell Emergence from Aortic Endothelium
    [作者:Swiers, G; Speck, NA; de Bruijn, MFTR,期刊:Cell Stem Cell, 页码:289-290 , 文章类型: Editorial Material,,卷期:2010年6-4]
  • Three recent Nature papers use time-lapse confocal imaging to visualize the birth of blood cells from the aortic endothelium. Two studies (Bertrand et al., 2010; Kissa and Herbomel, 2010) utilize the zebrafish embryo, wh...
  • Hooking Up with Oct4
    [作者:Lemischka, IR,期刊:Cell Stem Cell, 页码:291-292 , 文章类型: Editorial Material,,卷期:2010年6-4]
  • The transcription factor Oct4 plays a central role in controlling the undifferentiated state of embryonic and induced pluripotent stem cells. Two complementary papers in this issue of Cell Stem Cell describe the extended...
  • Cycling toward Elimination of Leukemic Stem Cells
    [作者:Goff, D; Jamieson, C,期刊:Cell Stem Cell, 页码:296-297 , 文章类型: Editorial Material,,卷期:2010年6-4]
  • In two recent articles in Science Translational Medicine and Nature Biotechnology, Saito et al. (2010) identify a molecular signature of acute myeloid leukemia (AML) stem cells and demonstrate that quiescent AML stem cel...