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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共44条记录   Novel Lipogenic Enzyme ELOVL7 Is Involved in Prostate Cancer Growth through Saturated Long-Chain Fatty Acid Metabolism [作者：Tamura, K; Makino, A; Hullin-Matsuda, F; Kobayashi, T; Furihata, M; Chung, S; Ashida, S; Miki, T; Fujioka, T; Shuin, T; Nakamura, Y; Nakagawa, H,期刊：Cancer research, 页码：8133-8140 , 文章类型： Article，,卷期：2009年69-20] A number of epidemiologic studies have indicated a strong association between dietary fat intake and prostate cancer development, suggesting that lipid metabolism plays some important roles in prostate carcinogenesis and... Increased Expression of Androgen Receptor Sensitizes Prostate Cancer Cells to Low Levels of Androgens [作者：Waltering, KK; Helenius, MA; Sahu, B; Manni, V; Linja, MJ; Janne, OA; Visakorpi, T,期刊：Cancer research, 页码：8141-8149 , 文章类型： Article，,卷期：2009年69-20] Androgen receptor (AR) is known to be overexpressed in castration-resistant prostate cancer. To interrogate the functional significance of the AR level, we established two LNCaP cell sublines expressing in a stable fashi... A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice [作者：Dupuy, AJ; Rogers, LM; Kim, J; Nannapaneni, K; Starr, TK; Liu, P; Largaespada, DA; Scheetz, TE; Jenkins, NA; Copeland, NG,期刊：Cancer research, 页码：8150-8156 , 文章类型： Article，,卷期：2009年69-20] Recent advances in cancer therapeutics stress the need for a better understanding of the molecular mechanisms driving tumor formation. This can be accomplished by obtaining a more complete description of the genes that c... microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells [作者：Wang, P; Zou, FD; Zhang, XD; Li, H; Dulak, A; Tomko, RJ; Lazo, JS; Wang, Z; Zhang, L; Yu, J,期刊：Cancer research, 页码：8157-8165 , 文章类型： Article，,卷期：2009年69-20] microRNAs (miRNA) are small noncoding RNAs that participate in diverse biological processes by suppressing target gene expression. Altered expression of miR-21 has been reported in cancer. To gain insights into its poten... Direct Evidence that Bevacizumab, an Anti-VEGF Antibody, Up-regulates SDF1 alpha, CXCR4, CXCL6, and Neuropilin 1 in Tumors from Patients with Rectal Cancer [作者：Xu, L; Duda, DG; di Tomaso, E; Ancukiewicz, M; Chung, DC; Lauwers, GY; Samuel, R; Shellito, P; Czito, BG; Lin, PC; Poleski, M; Bentley, R; Clark, JW; Willett, CG; Jain, RK,期刊：Cancer research, 页码：7905-7910 , 文章类型： Article，,卷期：2009年69-20] Clinical studies converge on the observation that circulating cytokines are elevated in most cancer patients by anti-vascular endothelial growth factor (VEGF) therapy. However, the source of these molecules and their rel... Combination of Sulindac and Antimicrobial Eradication of Helicobacter pylori Prevents Progression of Gastric Cancer in Hypergastrinemic INS-GAS Mice [作者：Lee, CW; Rickman, B; Rogers, AB; Muthupalani, S; Takaishi, S; Yang, PY; Wang, TC; Fox, JG,期刊：Cancer research, 页码：8166-8174 , 文章类型： Article，,卷期：2009年69-20] Helicobacter pylori infection causes severe dysplasia manifested as gastrointestinal intraepithelial neoplasia (GIN) after 28 weeks post-H. pylori infection (WPI) in cancer-prone, hypergastrinemic male INS-GAS mice. We e... Inhibition of Azoxymethane-Induced Colorectal Cancer by CP-31398, a TP53 Modulator, Alone or in Combination with Low Doses of Celecoxib in Male F344 Rats [作者：Rao, CV; Steele, VE; Swamy, MV; Patlolla, JMR; Guruswamy, S; Kopelovich, L,期刊：Cancer research, 页码：8175-8182 , 文章类型： Article，,卷期：2009年69-20] Tumor suppressor p53 plays a major role in colorectal cancer development. The present study explores the effects of p53-modulating agent CP-31398 alone and combined with celecoxib on azoxymethane-induced aberrant crypt f... Glomus Tumors in Neurofibromatosis Type 1: Genetic, Functional, and Clinical Evidence of a Novel Association (vol 69, pg 7393, 2009) [作者：Brems, H; Park, C; Maertens, O; Pemov, A; Messiaen, L; Upadhyaya, M; Claes, K; Beert, E; Peeters, K; Mautner, V; Sloan, JL; Yao, L; Lee, CCR; Sciot, R; De Smet, L; Legius, E; Stewart, DR,期刊：Cancer research, 页码：8216-8216 , 文章类型： Correction，,卷期：2009年69-20] A Novel PTEN-Dependent Link to Ubiquitination Controls FLIPs Stability and TRAIL Sensitivity in Glioblastoma Multiforme [作者：Panner, A; Crane, CA; Weng, CJ; Feletti, A; Parsa, AT; Pieper, RO,期刊：Cancer research, 页码：7911-7916 , 文章类型： Article，,卷期：2009年69-20] Phosphatase and tensin homologue (PTEN) loss and activation of the Akt-mammalian target of rapamycin (mTOR) pathway increases mRNA translation, increases levels of the antiapoptotic protein FLIPs, and confers resistance ... Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells [作者：Gosselin, K; Martien, S; Pourtier, A; Vercamer, C; Ostoich, P; Morat, L; Sabatier, L; Duprez, L; de Roodenbeke, CT; Gilson, E; Malaquin, N; Wernert, N; Slijepcevic, P; Ashtari, M; Chelli, F; Deruy, E; Vandenbunder, B; De Launoit, Y; Abbadie, C,期刊：Cancer research, 页码：7917-7925 , 文章类型： Article，,卷期：2009年69-20] Studies on human fibroblasts have led to viewing senescence as a barrier against tumorigenesis. Using keratinocytes, we show here that partially transformed and tumorigenic cells systematically and spontaneously emerge f... Molecular Consequences of Genetic Variations in the Glutathione Peroxidase 1 Selenoenzyme [作者：Zhuo, P; Goldberg, M; Herman, L; Lee, BS; Wang, HB; Brown, RL; Foster, CB; Peters, U; Diamond, AM,期刊：Cancer research, 页码：8183-8190 , 文章类型： Article，,卷期：2009年69-20] Accumulating data have implicated the selenium-containing cytosolic glutathione peroxidase, GPx-1, as a determinant of cancer risk and a mediator of the chemopreventive properties of selenium. Genetic variants of GPx-1 h... RAS Mutations Affect Tumor Necrosis Factor-Induced Apoptosis in Colon Carcinoma Cells via ERK-Modulatory Negative and Positive Feedback Circuits Along with Non-ERK Pathway Effects [作者：Kreeger, PK; Mandhana, R; Alford, SK; Haigis, KM; Lauffenburger, DA,期刊：Cancer research, 页码：8191-8199 , 文章类型： Article，,卷期：2009年69-20] More than 40% of colon cancers have a mutation in K-RAS or N-RAS, GTPases that operate as central hubs for multiple key signaling pathways within the cell. Utilizing an isogenic panel of colon carcinoma cells with K-RAS ... Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1 (vol 69, pg 7243, 2009) [作者：Folkins, C; Shaked, Y; Man, S; Tang, T; Lee, CR; Zhu, Z; Hoffman, RM; Kerbel, RS,期刊：Cancer research, 页码：8216-8216 , 文章类型： Correction，,卷期：2009年69-20] Genetic Alterations in the Phosphoinositide 3-Kinase/Akt Signaling Pathway Confer Sensitivity of Thyroid Cancer Cells to Therapeutic Targeting of Akt and Mammalian Target of Rapamycin (vol 69, pg 7311, 2009) [作者：Liu, D; Hou, P; Liu, Z; Wu, G; Xing, M,期刊：Cancer research, 页码：8216-8216 , 文章类型： Correction，,卷期：2009年69-20] In vivo, Noninvasive, Label-Free Detection and Eradication of Circulating Metastatic Melanoma Cells Using Two-Color Photoacoustic Flow Cytometry with a Diode Laser [作者：Galanzha, EI; Shashkov, EV; Spring, PM; Suen, JY; Zharov, VP,期刊：Cancer research, 页码：7926-7934 , 文章类型： Article，,卷期：2009年69-20] The circulating tumor cell (CTC) count has been shown as a prognostic marker for metastasis development. However, its clinical utility for metastasis prevention remains unclear, because metastases may already be present ... EBV-Induced Human CD8(+) NKT Cells Suppress Tumorigenesis by EBV-Associated Malignancies [作者：He, YL; Xiao, RJ; Li, L; Ji, X; Zhou, R; Wang, YJ; Zhang, LJ; Du, CX; Tan, XT; Xiao, W; Chen, L; Jiang, YP; Xiong, T; Wu, MJ; Xiong, J; Jin, YX; Tan, JQ,期刊：Cancer research, 页码：7935-7944 , 文章类型： Article，,卷期：2009年69-20] The underlying mechanism of the protective and suppressive role of NKT cells in human tumor immunosurveillance remains to be fully elucidated. We show that the frequencies of CD8(+) NKT cells in patients with EBV-associa...