- The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis
[作者：Dopeso, H; Mateo-Lozano, S; Mazzolini, R; Rodrigues, P; Lagares-Tena, L; Ceron, J; Romero, J; Esteves, M; Landolfi, S; Hernandez-Losa, J; Castano, J; Wilson, AJ; Cajal, SRY; Mariadason, JM; Schwartz, S; Arango, D,期刊：Cancer research, 页码：7430-7438 , 文章类型： Article，,卷期：2009年69-18]
- Colorectal cancer is the second cause of cancer-related death in the western world, and although the genetic and molecular mechanisms involved in the initiation and progression of these tumors are among the best characte...
- Elevated Epithelial Insulin-like Growth Factor Expression Is a Risk Factor for Lung Cancer Development
[作者：Kim, WY; Jin, Q; Oh, SH; Kim, ES; Yang, YJ; Lee, DH; Feng, L; Behrens, C; Prudkin, L; Millers, YE; Lee, JJ; Lippman, SM; Hong, WK; Wistuba, II; Lee, HY,期刊：Cancer research, 页码：7439-7448 , 文章类型： Article，,卷期：2009年69-18]
- Insulin-like growth factor (IGF)-I receptor (IGF-IR) signaling has been implicated in several human neoplasms. However, the role of serum levels of IGFs in lung cancer risk is controversial. We assessed the role of tissu...
- KDR Activating Mutations in Human Angiosarcomas Are Sensitive to Specific Kinase Inhibitors
[作者：Antonescu, CR; Yoshida, A; Guo, TH; Chang, NE; Zhang, L; Agaram, NP; Qin, LX; Brennan, MF; Singer, S; Maki, RG,期刊：Cancer research, 页码：7175-7179 , 文章类型： Article，,卷期：2009年69-18]
- Angiosarcomas (AS) represent a heterogeneous group of malignant vascular tumors occurring not only in different anatomic locations but also in distinct clinical settings, such as radiation or associated chronic lymphedem...
- Insulin Receptor Substrate-1 Suppresses Transforming Growth Factor-beta 1-Mediated Epithelial-Mesenchymal Transition
[作者：Shi, J; Wang, DM; Wang, CM; Hu, Y; Liu, AH; Zhang, YL; Sun, B; Song, JG,期刊：Cancer research, 页码：7180-7187 , 文章类型： Article，,卷期：2009年69-18]
- We investigated the regulatory effect of insulin receptor substrate-1 (IRS-1) on transforming growth factor-beta 1 (TGF-beta 1)-induced epithelial-mesenchymal transition (EMT). TGF-beta 1-induced EMT and cell migration i...
- Resveratrol Suppresses Growth of Human Ovarian Cancer Cells in Culture and in a Murine Xenograft Model: Eukaryotic Elongation Factor 1A2 as a Potential Target
[作者：Lee, MH; Choi, BY; Kundu, JK; Shin, YK; Na, HK; Surh, YJ,期刊：Cancer research, 页码：7449-7458 , 文章类型： Article，,卷期：2009年69-18]
- The eukaryotic elongation factor 1A2 (eEF1A2) is known to retain oncogenic potential and is recognized as a novel target for cancer prevention and therapy. Resveratrol (trans-3,4',5-trihydroxystilbene), a phytoalexin pre...
- A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis
[作者：Saetrom, P; Biesinger, J; Li, SM; Smith, D; Thomas, LF; Majzoub, K; Rivas, GE; Alluin, J; Rossi, JJ; Krontiris, TG; Weitzel, J; Daly, MB; Benson, AB; Kirkwood, JM; O'Dwyer, PJ; Sutphen, R; Stewart, JA; Johnson, D; Larson, GP,期刊：Cancer research, 页码：7459-7465 , 文章类型： Article，,卷期：2009年69-18]
- MicroRNAs regulate diverse cellular processes and play an integral role in cancer pathogenesis. Genomic variation within miRNA target sites may therefore be important sources for genetic differences in cancer risk. To in...
- Mouse Mammary Tumor Virus p75 and p110 CUX1 Transgenic Mice Develop Mammary Tumors of Various Histologic Types
[作者：Cadieux, C; Kedinger, V; Yao, L; Vadnais, C; Drossos, M; Paquet, M; Nepveu, A,期刊：Cancer research, 页码：7188-7197 , 文章类型： Article，,卷期：2009年69-18]
- The p75 and p110 isoforms of the CUX1 homeodomain protein are overexpressed in breast tumors and cancer cell lines. To assess and compare the ability of these short CUX1 isoforms in driving mammary tumor development, we ...
- NEDD9 Promotes Oncogenic Signaling in Mammary Tumor Development
[作者：Izumchenko, E; Singh, MK; Plotnikova, OV; Tikhmyanova, N; Little, JL; Serebriiskii, IG; Seo, S; Kurokawa, M; Egleston, BL; Klein-Szanto, A; Pugacheva, EN; Hardy, RR; Wolfson, M; Connolly, DC; Golemis, EA,期刊：Cancer research, 页码：7198-7206 , 文章类型： Article，,卷期：2009年69-18]
- In the past 3 years, altered expression of the HEF1/CAS-L/NEDD9 scaffolding protein has emerged as contributing to cancer metastasis in multiple cancer types. However, whereas some studies have identified elevated NEDD9 ...
- Inhibition of Tumor Growth Progression by Antiandrogens and mTOR Inhibitor in a Pten-Deficient Mouse Model of Prostate Cancer
[作者：Zhang, WS; Zhu, J; Efferson, CL; Ware, C; Tammam, J; Angagaw, M; Laskey, J; Bettano, KA; Kasibhatla, S; Reilly, JF; Sur, C; Majumder, PK,期刊：Cancer research, 页码：7466-7472 , 文章类型： Article，,卷期：2009年69-18]
- Androgen receptors have been shown to play a critical role in prostate cancer. We used ultrasound imaging techniques to track tumor response to antiandrogen and rapamycin treatment in a prostate-specific Pten-deleted mou...
- Parathyroid Hormone-Related Protein Protects against Mammary Tumor Emergence and Is Associated with Monocyte Infiltration in Ductal Carcinoma In situ
[作者：Fleming, NI; Trivett, MK; George, J; Slavin, JL; Murray, WK; Moseley, JM; Anderson, RL; Thomas, DM,期刊：Cancer research, 页码：7473-7479 , 文章类型： Article，,卷期：2009年69-18]
- Parathyroid hormone-related protein (PTHrP) is required for mammary gland development and promotes the growth of breast cancer metastases within bone. However, there are conflicting reports of the prognostic significance...
- Tumor Immunology: New Perspectives
[作者：McArdle, SE; Rees, RC,期刊：Cancer research, 页码：7157-7159 , 文章类型： Editorial Material，,卷期：2009年69-18]
- This second meeting, organized by the Cancer Immunology Working Group of AACR, concentrated mainly on three areas of importance; these included (a) ways to increase the success rate of vaccination by improving the peptid...
- A Genetic Variant of Aurora Kinase A Promotes Genomic Instability Leading to Highly Malignant Skin Tumors
[作者：Torchia, EC; Chen, YY; Sheng, H; Katayama, H; Fitzpatrick, J; Brinkley, WR; Caulin, C; Sen, S; Roop, DR,期刊：Cancer research, 页码：7207-7215 , 文章类型： Article，,卷期：2009年69-18]
- Aurora kinase A (Aurora-A) belongs to a highly conserved family of mitotis-regulating serine/threonine kinases implicated in epithelial cancers. Initially we examined Aurora-A expression levels at different stages of hum...
- Epigenetic Loss of Mucosa-Associated Lymphoid Tissue 1 Expression in Patients with Oral Carcinomas
[作者：Chiba, T; Maeda, G; Kawashiri, S; Kato, K; Imai, K,期刊：Cancer research, 页码：7216-7223 , 文章类型： Article，,卷期：2009年69-18]
- Mucosa-associated lymphoid tissue 1 (MALT1), which is located in a genomic region that encodes unknown tumor suppressor gene(s), activates nuclear factor-kappa B in lymphocyte lineages. However, its expression and role i...
- Development and Cancer: At the Crossroads of Nodal and Notch Signaling
[作者：Strizzi, L; Hardy, KM; Seftor, EA; Costa, FF; Kirschmann, DA; Seftor, REB; Postovit, LM; Hendrix, MJC,期刊：Cancer research, 页码：7131-7134 , 文章类型： Review，,卷期：2009年69-18]
- Aggressive tumor cells express a plastic, multipotent phenotype similar to embryonic stem cells. However, the absence of major regulatory checkpoints in these tumor cells allows aberrant activation of embryonic signaling...
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