Structure————————个性化文献订阅—

Zernike Phase Plate Cryoelectron Microscopy Facilitates Single Particle Analysis of Unstained Asymmetric Protein Complexes
[作者：Chang, WH; Chiu, MTK; Chen, CY; Yen, CF; Lin, YC; Weng, YP; Chang, JC; Wu, YM; Cheng, H; Fu, JH; Tu, IP,期刊：Structure, 页码：17-27 , 文章类型： Article，,卷期：2010年18-1]
Single particle reconstruction from cryoelectron microscopy images, though emerging as a powerful means in structural biology, is faced with challenges as applied to asymmetric proteins smaller than megadaltons due to lo...

Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces
[作者：Shandilya, SMD; Nalam, MNL; Nalivaika, EA; Gross, PJ; Valesano, JC; Shindo, K; Li, M; Munson, M; Royer, WE; Harjes, E; Kono, T; Matsuo, H; Harris, RS; Somasundaran, M; Schiffer, CA,期刊：Structure, 页码：28-38 , 文章类型： Article，,卷期：2010年18-1]
APOBEC3G is a DNA cytidine deaminase that has antiviral activity against HIV-1 and other pathogenic viruses. In this study the crystal structure of the catalytically active C-terminal domain was determined to 2.25 ang...

Probing the Interactions of Carboxy-atractyloside and Atractyloside with the Yeast Mitochondrial ADP/ATP Carrier
[作者：Kedrov, A; Hellawell, AM; Klosin, A; Broadhurst, RB; Kunji, ERS; Muller, DJ,期刊：Structure, 页码：39-46 , 文章类型： Article，,卷期：2010年18-1]
Mitochondrial ADP/ATP carriers are inhibited by two natural compounds, atractyloside (ATR) or carboxyatractyloside (CATR), which differ by one carboxylate group. The interactions of the inhibitors with the carrier were i...

Three-Dimensional Visualization of Gammaherpesvirus Life Cycle in Host Cells by Electron Tomography
[作者：Peng, L; Ryazantsev, S; Sun, R; Zhou, ZH,期刊：Structure, 页码：47-58 , 文章类型： Article，,卷期：2010年18-1]
Gammaherpesviruses are etiologically associated with human tumors. A three-dimensional (3D) examination of their life cycle in the host is lacking, significantly limiting our understanding of the structural and molecular...

A TNF-like Trimeric Lectin Domain from Burkholdeda cenocepacia with Specificity for Fucosylated Human Histo-Blood Group Antigens
[作者：Sulak, O; Cioci, G; Delia, M; Lahmann, M; Varrot, A; Imberty, A; Wimmerova, M,期刊：Structure, 页码：59-72 , 文章类型： Article，,卷期：2010年18-1]
The opportunistic pathogen Burkholderia cenocepacia expresses several soluble lectins, among them BC2L-C. This lectin exhibits two domains: a C-terminal domain with high sequence similarity to the recently described calc...

Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence
[作者：Kuryavyi, V; Patel, DJ,期刊：Structure, 页码：73-82 , 文章类型： Article，,卷期：2010年18-1]
We report on the solution structure of an unprecedented intramolecular G-quadruplex formed by the guanosine-rich human chl1 intronic d(G(3)-N-G(4)-N-2-G(4)-N-G(3)-N) 19-mer sequence in K+-containing solution. This G-quad...

The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis
[作者：Golosov, AA; Warren, JJ; Beese, LS; Karplus, M,期刊：Structure, 页码：83-93 , 文章类型： Article，,卷期：2010年18-1]
High-fidelity DNA polymerases copy DNA rapidly and accurately by adding correct deoxynucleotide triphosphates to a growing primer strand of DNA. Following nucleotide incorporation, a series of conformational changes tran...

Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway
[作者：Akey, DL; Razelun, JR; Tehranisa, J; Sherman, DH; Gerwick, WH; Smith, JL,期刊：Structure, 页码：94-105 , 文章类型： Article，,卷期：2010年18-1]
Modular polyketide synthases (PKS) make novel natural products through a series of preprogrammed chemical steps catalyzed by an assembly line of multidomain modules. Each assembly-line step involves unique extension a...

Structural Basis of Host Cell Recognition by the Pilus Adhesin from Streptococcus pneumoniae
[作者：Izore, T; Contreras-Martel, C; El Mortaji, L; Manzano, C; Terrasse, R; Vernet, T; Di Guilmi, AM; Dessen, A,期刊：Structure, 页码：106-115 , 文章类型： Article，,卷期：2010年18-1]
Pili are fibrous virulence factors associated directly to the bacterial surface that play critical roles in adhesion and recognition of host cell receptors. The human pathogen Streptococcus pneumoniae carries a single pi...

Conformational Changes in Guanylate Cyclase-Activating Protein 1 Induced by Ca2+ and N-Terminal Fatty Acid Acylation
[作者：Orban, T; Bereta, G; Miyagi, M; Wang, BL; Chance, MR; Sousa, MC; Palczewski, K,期刊：Structure, 页码：116-126 , 文章类型： Article，,卷期：2010年18-1]
Neuronal Ca2+ sensors (NCS) are high-affinity Ca2+ binding proteins critical for regulating a vast range of physiological processes. Guanylate cyclase-activating proteins (GCAPs) are members of the NCS family responsible...

Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic
[作者：Perry, K; Hwang, Y; Bushman, FD; Van Duyne, GD,期刊：Structure, 页码：127-137 , 文章类型： Article，,卷期：2010年18-1]
Poxviruses encode their own type IB topoisomerases (TopIBs), which release superhelical tension generated by replication and transcription of their genomes. To investigate the reaction catalyzed by viral TopIBs, we have ...

Crystal Structure of UbcH5b similar to Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2 similar to Ub Conjugates
[作者：Sakata, E; Satoh, T; Yamamoto, S; Yamaguchi, Y; Yagi-Utsumi, M; Kurimoto, E; Tanaka, K; Wakatsuki, S; Kato, K,期刊：Structure, 页码：138-147 , 文章类型： Article，,卷期：2010年18-1]
E2 ubiquitin-conjugating enzymes catalyze the attachment of ubiquitin to lysine residues of target proteins. The UbcH5b E2 enzyme has been shown to play a key role in the initiation of the ubiquitination of substrate ...

Reverse Micelle Encapsulation of Membrane-Anchored Proteins for Solution NMR Studies
[作者：Valentine, KG; Peterson, RW; Saad, JS; Summers, MF; Xu, XZ; Ames, JB; Wand, AJ,期刊：Structure, 页码：9-16 , 文章类型： Article，,卷期：2010年18-1]
Perhaps 5%-10% of proteins bind to membranes via a covalently attached lipid. Posttranslational attachment of fatty acids such as myristate occurs on a variety of viral and cellular proteins. High-resolution information ...