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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共42条记录   Establishment of an Improved Mouse Model for Infantile Neuroaxonal Dystrophy That Shows Early Disease Onset and Bears a Point Mutation in Pla296 [作者：Wada, H; Yasuda, T; Miura, I; Watabe, K; Sawa, C; Kamijuku, H; Kojo, S; Taniguchi, M; Nishino, I; Wakana, S; Yoshida, H; Seino, K,期刊：American Journal of Pathology, 页码：2257-2263 , 文章类型： Article，,卷期：2009年175-6] Calcium-independent group VIA phospholipase A, (iPLA,P), encoded by PLA2G6, has been shown to be involved in various physiological and pathological processes, including immunity, cell death, and cell membrane homeostasis... Novel Biomarkers for Prostate Cancer Including Noncoding Transcripts [作者：Romanuik, TL; Ueda, T; Le, N; Haile, S; Yong, TMK; Thomson, T; Vessella, RL; Sadar, MD,期刊：American Journal of Pathology, 页码：2264-2276 , 文章类型： Article，,卷期：2009年175-6] Levels of 27 transcripts were investigated as potential novel markers for prostate cancer, including genes encoding plasma membrane proteins (ADAM2, ELOVL5, MARCKSL1, RAMP1, TMEM30A, and TMEM66); secreted proteins (SPON2... Gla-Rich Protein Is a Novel Vitamin K-Dependent Protein Present in Serum That Accumulates at Sites of Pathological Calcifications [作者：Viegas, CSB; Cavaco, S; Neves, PL; Ferreira, A; Joao, A; Williamson, MK; Price, PA; Cancela, ML; Simes, DC,期刊：American Journal of Pathology, 页码：2288-2298 , 文章类型： Article，,卷期：2009年175-6] Mineralization of soft tissues is an abnormal process that occurs in any body tissue and can greatly increase morbidity and mortality. Vitamin K-dependent (VKD) proteins play a crucial role in these processes; matrix Gla... Identification of EpCAM as a Molecular Target of Prostate Cancer Stroma [作者：Mukherjee, S; Richardson, AM; Rodriguez-Canales, J; Ylaya, K; Erickson, HS; Player, A; Kawasaki, ES; Pinto, PA; Choyke, PL; Merino, MJ; Albert, PS; Chuaqui, RF; Emmert-Buck, MR,期刊：American Journal of Pathology, 页码：2277-2287 , 文章类型： Article，,卷期：2009年175-6] To delineate the molecular changes that occur in the tumor microenvironment, we previously performed global transcript analysis of human prostate cancer specimens using tissue microdissection and expression microarrays. ... Matrilysin (Matrix Metalloproteinase-7) Regulates Anti-Inflammatory and Antifibrotic Pulmonary Dendritic Cells That Express CD103 (alpha(E)beta(7)-Integrin) [作者：Manicone, AM; Huizar, I; McGuire, JK,期刊：American Journal of Pathology, 页码：2319-2331 , 文章类型： Article，,卷期：2009年175-6] The E-cadhcrin receptor CD103 (alpha(E)beta(7)-integrin) is expressed on specific populations of pulmonary dendritic cells (DC) and T cells. However, CD103 function in the lung is not well understood. Matrilysin (MMP-7) ... Neuroprotective Effect of Oligodendrocyte Precursor Cell Transplantation in a Long-Term Model of Periventricular Leukomalacia [作者：Webber, DJ; van Blitterswijk, M; Chandran, S,期刊：American Journal of Pathology, 页码：2332-2342 , 文章类型： Article，,卷期：2009年175-6] Perinatal white matter injury, or periventricular leukomalacia (PVL), is the most common cause of brain injury in premature infants and is the leading cause of cerebral palsy. Despite increasing numbers of surviving extr... Dysferlin Deficiency and the Development of Cardiomyopathy in a Mouse Model of Limb-Girdle Muscular Dystrophy 2B [作者：Chase, TH; Cox, GA; Burzenski, L; Foreman, O; Shultz, LD,期刊：American Journal of Pathology, 页码：2299-2308 , 文章类型： Article，,卷期：2009年175-6] Limb-girdle muscular dystrophy 211, Miyoslil myopathy, and distal myopathy of anterior tibialis are severely debilitating muscular dystrophies caused by genetically determined dysferlin deficiency. in these muscular dyst... Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice [作者：Mirza, R; DiPietro, LA; Koh, TJ,期刊：American Journal of Pathology, 页码：2454-2462 , 文章类型： Article，,卷期：2009年175-6] Macrophages are thought to play important roles during wound healing, but definition of these roles has been hampered by our technical inability to specifically eliminate macrophages during wound repair. The purpose of t... Epithelial Mesenchymal Transition in Human Ocular Chronic Graft-Versus-Host Disease [作者：Ogawa, Y; Shimmura, S; Kawakita, T; Yoshida, S; Kawakami, Y; Tsubota, K,期刊：American Journal of Pathology, 页码：2372-2381 , 文章类型： Article，,卷期：2009年175-6] Chronic graft-versus-host disease (cGVHD) of the ocular surface and lacrimal gland is a vision-threatening condition that occurs after allogencic bone marrow transplantation. in this study, we used imunohistochemistry an... Signal Regulatory Protein-beta 1 A Microglial Modulator of Phagocytosis in Alzheimer's Disease [作者：Gaikwad, S; Larionov, S; Wang, Y; Dannenberg, H; Matozaki, T; Monsonego, A; Thal, DR; Neumann, H,期刊：American Journal of Pathology, 页码：2528-2539 , 文章类型： Article，,卷期：2009年175-6] The signal regulatory protein-beta 1 (SIRP beta 1) is a DAP12-associated transmembrane receptor expressed in a subset of hematopoietic cells. Recently, it was shown that peritoneal macrophages express SIRP beta 1, which ... Pseudomonas aeruginosa Exotoxin Pyocyanin Causes Cystic Fibrosis Airway Pathogenesis [作者：Caldwell, CC; Chen, Y; Goetzmann, HS; Hao, YH; Borchers, MT; Hassett, DJ; Young, LR; Mavrodi, D; Thomashow, L; Lau, GW,期刊：American Journal of Pathology, 页码：2473-2488 , 文章类型： Article，,卷期：2009年175-6] The cystic fibrosis (CF) airway bacterial pathogen Pseudomonas aeruginosa secretes multiple virulence factors. Among these, the redox active exotoxin pyocyanin (PCN) is produced in concentrations up to 100 mu mol/L durin... Increased Activity and Altered Subcellular Distribution of Lysosomal Enzymes Determine Neuronal Vulnerability in Niemann-Pick Type C1-Deficient Mice [作者：Amritraj, A; Peake, K; Kodam, A; Salio, C; Merighi, A; Vance, JE; Kar, S,期刊：American Journal of Pathology, 页码：2540-2556 , 文章类型： Article，,卷期：2009年175-6] Niemann-Pick disease type C (NPC), caused by mutations in the Npc1 or Npc2 genes, is a progressive neurodegenerative disorder characterized by intracellular accumulation/redistribution of cholesterol in a number of tissu... Similarities between Forms of Sheep Scrapie and Creutzfeldt-Jakob Disease Are Encoded by Distinct Prion Types [作者：Wemheuer, WM; Benestad, SL; Wrede, A; Schulze-Sturm, U; Wemheuer, WE; Hahmann, U; Gawinecka, J; Schutz, E; Zerr, I; Brenig, B; Bratberg, B; Andreoletti, O; Schulz-Schaeffer, WJ,期刊：American Journal of Pathology, 页码：2566-2573 , 文章类型： Article，,卷期：2009年175-6] Transmissible spongiform encephalopathies such as scrapie in sheep, Creutzfeldt-Jakob disease (CJD) in humans, and bovine sporadic encephalopathy in cattle are characterized by the accumulation of a mis-folded protein: t... Phenolic Compounds Prevent Alzheimer's Pathology through Different Effects on the Amyloid-beta Aggregation Pathway [作者：Hamaguchi, T; Ono, K; Murase, A; Yamada, M,期刊：American Journal of Pathology, 页码：2557-2565 , 文章类型： Article，,卷期：2009年175-6] Inhibition of amyloid-beta (A beta) aggregation is an attractive therapeutic strategy for Alzheimer's disease (AD). Certain phenolic compounds have been reported to have anti-A beta aggregation effects in vitro. This stu... High Expression of the PAX3-FKHR Oncoprotein Is Required to Promote Tumorigenesis of Human Myoblasts [作者：Xia, SJ; Holder, DD; Pawel, BR; Zhang, CN; Barr, FG,期刊：American Journal of Pathology, 页码：2600-2608 , 文章类型： Article，,卷期：2009年175-6] PAX3-FKHR is a fusion oncoprotein generated by the 2;13 chromosomal translocation in alveolar rhabdomyosarcoma (ARMS), a cancer associated with the skeletal muscle lineage. Previous studies determined that high-level PAX... Cell Death and Learning Impairment in Mice Caused by in Vitro Modified Pro-NGF Can Be Related to Its Increased Oxidative Modifications in Alzheimer Disease [作者：Kichev, A; Ilieva, EV; Pinol-Ripoll, G; Podlesniy, P; Ferrer, I; Portero-Otin, M; Pamplona, R; Espinet, C,期刊：American Journal of Pathology, 页码：2574-2585 , 文章类型： Article，,卷期：2009年175-6] Pro-nerve growth factor (pro-NGF) is expressed at increased levels in Alzheimer's disease (AD)-affected brains and is able to induce cell death in cultures; however, the reasons for these phenomena remain elusive. Here w...