- How I treat postthrombotic syndrome
[作者：Kahn, SR,期刊：Blood, 页码：4624-4631 , 文章类型： Article，,卷期：2009年114-21]
- Postthrombotic syndrome (PTS) is a chronic complication of deep venous thrombosis (DVT) that reduces quality of life and has important socioeconomic consequences. More than one-third of patients with DVT will develop PTS...
- Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury
[作者：Adamkiewicz, TV; Abboud, MR; Paley, C; Olivieri, N; Kirby-Allen, M; Vichinsky, E; Casella, JF; Alvarez, OA; Barredo, JC; Lee, MT; Iyer, RV; Kutlar, A; McKie, KM; McKie, V; Odo, N; Gee, B; Kwiatkowski, JL; Woods, GM; Coates, T; Wang, W; Adams, RJ,期刊：Blood, 页码：4632-4638 , 文章类型： Article，,卷期：2009年114-21]
- Chronic blood transfusion is increasingly indicated in patients with sickle cell disease. Measuring resulting iron overload remains a challenge. Children without viral hepatitis enrolled in 2 trials for stroke prevention...
- Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease
[作者：Gordeuk, VR; Campbell, A; Rana, S; Nouraie, M; Niu, XM; Minniti, CP; Sable, C; Darbari, D; Dham, N; Onyekwere, O; Ammosova, T; Nekhai, S; Kato, GJ; Gladwin, MT; Castro, OL,期刊：Blood, 页码：4639-4644 , 文章类型： Article，,卷期：2009年114-21]
- Hydroxyurea and higher hemoglobin F improve the clinical course and survival in sickle cell disease, but their roles in protecting from pulmonary hypertension are not clear. We studied 399 children and adolescents with s...
- The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish
[作者：Amigo, JD; Ackermann, GE; Cope, JJ; Yu, M; Cooney, JD; Ma, DD; Langer, NB; Shafizadeh, E; Shaw, GC; Horsely, W; Trede, NS; Davidson, AJ; Barut, BA; Zhou, Y; Wojiski, SA; Traver, D; Moran, TB; Kourkoulis, G; Hsu, K; Kanki, JP; Shah, DI; Lin, HF; Handin, RI; Cantor, AB; Paw, BH,期刊：Blood, 页码：4654-4663 , 文章类型： Article，,卷期：2009年114-21]
- The nuclear protein FOG-1 binds transcription factor GATA-1 to facilitate erythroid and megakaryocytic maturation. However, little is known about the function of FOG-1 during myeloid and lymphoid development or how FOG-1...
- Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
[作者：Van den Bossche, J; Bogaert, P; van Hengel, J; Guerin, CJ; Berx, G; Movahedi, K; Van den Bergh, R; Pereira-Fernandes, A; Geuns, JMC; Pircher, H; Dorny, P; Grooten, J; De Baetselier, P; Van Ginderachter, JA,期刊：Blood, 页码：4664-4674 , 文章类型： Article，,卷期：2009年114-21]
- Alternatively activated macrophages (AAMs), triggered by interleukin-4 (IL-4) and IL-13, play a modulating role during Th2 cytokine-driven pathologies, but their molecular armament remains poorly characterized. Here, we ...
- High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia
[作者：Herling, M; Patel, KA; Weit, N; Lilienthal, N; Hallek, M; Keating, MJ; Jones, D,期刊：Blood, 页码：4675-4686 , 文章类型： Article，,卷期：2009年114-21]
- Although activation of the B-cell receptor (BCR) signaling pathway is implicated in the pathogenesis of chronic lymphocytic leukemia (CLL), its clinical impact and the molecular correlates of such response are not clearl...
- VH4-34(+) hairy cell leukemia, a new variant with poor prognosis despite standard therapy
[作者：Arons, E; Suntum, T; Stetler-Stevenson, M; Kreitman, RJ,期刊：Blood, 页码：4687-4695 , 文章类型： Article，,卷期：2009年114-21]
- Hairy cell leukemia variant (HCLv) presents with high disease burden, lack of typical antigens like CD25, and poor response to standard treatments like cladribine. Occasionally, patients with classic HCL respond poorly. ...
- Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior
[作者：Forconi, F; Sozzi, E; Cencini, E; Zaja, F; Intermesoli, T; Stelitano, C; Rigacci, L; Gherlinzoni, F; Cantaffa, R; Baraldi, A; Gallamini, A; Zaccaria, A; Pulsoni, A; Gobbi, M; Tassi, M; Raspadori, D; Leoncini, L; Rinaldi, A; Sabattini, E; Bertoni, F; Pileri, SA; Lauria, F,期刊：Blood, 页码：4696-4702 , 文章类型： Article，,卷期：2009年114-21]
- Hairy cell leukemia (HCL) is generally responsive to single-agent cladribine, and only a minority of patients are refractory and with poor prognosis. HCLs generally express mutated ( M) and, in a minority, unmutated (UM)...
- TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia
[作者：Costantini, JL; Cheung, SMS; Hou, S; Li, HZ; Kung, SK; Johnston, JB; Wilkins, JA; Gibson, SB; Marshall, AJ,期刊：Blood, 页码：4703-4712 , 文章类型： Article，,卷期：2009年114-21]
- Tandem pleckstrin homology domain proteins (TAPPs) are recruited to the plasma membrane via binding to phosphoinositides produced by phosphoinositide 3-kinases (PI3Ks). Whereas PI3Ks are critical for B-cell activation, t...
- Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy
[作者：Ramsay, AG; Clear, AJ; Kelly, G; Fatah, R; Matthews, J; MacDougall, F; Lister, TA; Lee, AM; Calaminici, M; Gribben, JG,期刊：Blood, 页码：4713-4720 , 文章类型： Article，,卷期：2009年114-21]
- An important hallmark of cancer progression is the ability of tumor cells to evade immune recognition. Understanding the relationship between neoplastic cells and the immune microenvironment should facilitate the design ...
- The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis
[作者：Kimura, A; Rieger, MA; Simone, JM; Chen, WP; Wickre, MC; Zhu, BM; Hoppe, PS; O'Shea, JJ; Schroeder, T; Hennighausen, L,期刊：Blood, 页码：4721-4728 , 文章类型： Article，,卷期：2009年114-21]
- Neutrophils play a vital role in the immune defense, which is evident by the severity of neutropenia causing life-threatening infections. Granulocyte macrophage-colony stimulating factor (GM-CSF) controls homeostatic and...
|