- How I treat age-related morbidities in elderly persons with hemophilia
[作者：Mannucci, PM; Schutgens, REG; Santagostino, E; Mauser-Bunschoten, EP,期刊：Blood, 页码：5256-5263 , 文章类型： Article，,卷期：2009年114-26]
- In persons with hemophilia, life expectancy is now approaching that of the general male population, at least in countries that can afford regular replacement therapy with coagulation factor concentrates. The new challeng...
- Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation
[作者：Kroger, N; Holler, E; Kobbe, G; Bornhauser, M; Schwerdtfeger, R; Baurmann, H; Nagler, A; Bethge, W; Stelljes, M; Uharek, L; Wandt, H; Burchert, A; Corradini, P; Schubert, J; Kaufmann, M; Dreger, P; Wulf, GG; Einsele, H; Zabelina, T; Kvasnicka, HM; Thiele, J; Brand, R; Zander, AR; Niederwieser, D; de Witte, TM,期刊：Blood, 页码：5264-5270 , 文章类型： Article，,卷期：2009年114-26]
- From 2002 to 2007, 103 patients with primary myelofibrosis or postessential thrombocythemia and polycythemia vera myelofibrosis and a median age of 55 years (range, 32-68 years) were included in a prospective multicenter...
- Epidemiologic study on survival of chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia patients with BCR-ABL T315I mutation
[作者：Nicolini, FE; Mauro, MJ; Martinelli, G; Kim, DW; Soverini, S; Muller, MC; Hochhaus, A; Cortes, J; Chuah, C; Dufva, IH; Apperley, JF; Yagasaki, F; Pearson, JD; Peter, S; Rodriguez, CS; Preudhomme, C; Giles, F; Goldman, JM; Zhou, W,期刊：Blood, 页码：5271-5278 , 文章类型： Article，,卷期：2009年114-26]
- The BCR-ABL T315I mutation represents a major mechanism of resistance to tyrosine kinase inhibitors (TKIs). The objectives of this retrospective observational study were to estimate overall and progression-free survival ...
- TLR8-dependent TNF-alpha overexpression in Fanconi anemia group C cells
[作者：Vanderwerf, SM; Svahn, J; Olson, S; Rathbun, RK; Harrington, C; Yates, J; Keeble, W; Anderson, DC; Anur, P; Pereira, NF; Pilonetto, DV; Pasquini, R; Bagby, GC,期刊：Blood, 页码：5290-5298 , 文章类型： Article，,卷期：2009年114-26]
- Tumor necrosis factor alpha (TNF-alpha) production is abnormally high in Fanconi anemia (FA) cells and contributes to the hematopoietic defects seen in FA complementation group C-deficient (Fancc(-/-)) mice. Applying gen...
- Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling
[作者：Banh, C; Fugere, C; Brossay, L,期刊：Blood, 页码：5299-5306 , 文章类型： Article，,卷期：2009年114-26]
- KLRG1 is an inhibitory receptor expressed on a subset of mature T and NK cells. Recently, E-, N-, and R-cadherin have been identified as ligands for KLRG1. Cadherins are a large family of transmembrane or membrane-associ...
- Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage
[作者：Malcikova, J; Smardova, J; Rocnova, L; Tichy, B; Kuglik, P; Vranova, V; Cejkova, S; Svitakova, M; Francova, HS; Brychtova, Y; Doubek, M; Brejcha, M; Klabusay, M; Mayer, J; Pospisilova, S; Trbusek, M,期刊：Blood, 页码：5307-5314 , 文章类型： Article，,卷期：2009年114-26]
- Deletion of TP53 gene, under routine assessment by fluorescence in situ hybridization analysis, connects with the worst prognosis in chronic lymphocytic leukemia (CLL). The presence of isolated TP53 mutation (without del...
- BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt
[作者：Juszczynski, P; Chen, LF; O'Donnell, E; Polo, JM; Ranuncolo, SM; Dalla-Favera, R; Melnick, A; Shipp, MA,期刊：Blood, 页码：5315-5321 , 文章类型： Article，,卷期：2009年114-26]
- Tonic B-cell receptor (BCR) signaling is a key survival pathway during normal B-cell ontogenesis and in a subset of diffuse large B-cell lymphomas (DLBCLs). We previously demonstrated that BCR-dependent DLBCL cell lines ...
- Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo model
[作者：Wang, SY; Veeramani, S; Racila, E; Cagley, J; Fritzinger, DC; Vogel, CW; John, WS; Weiner, GJ,期刊：Blood, 页码：5322-5330 , 文章类型： Article，,卷期：2009年114-26]
- Growing evidence indicates antibody-dependent cellular cytotoxicity (ADCC) contributes to the clinical response to monoclonal antibody (mAb) therapy of lymphoma. Recent in vitro analysis suggests C3b can inhibit mAb-indu...
- MicroRNA 29b functions in acute myeloid leukemia
[作者：Garzon, R; Heaphy, CEA; Havelange, V; Fabbri, M; Volinia, S; Tsao, T; Zanesi, N; Kornblau, SM; Marcucci, G; Calin, GA; Andreeff, M; Croce, CM,期刊：Blood, 页码：5331-5341 , 文章类型： Article，,卷期：2009年114-26]
- MicroRNAs (miRNAs) are associated with cytogenetics and molecular subtypes of acute myelogeneous leukemia (AML), but their impact on AML pathogenesis is poorly understood. We have previously shown that miR-29b expression...
- Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs
[作者：Aichberger, KJ; Gleixner, KV; Mirkina, I; Cerny-Reiterer, S; Peter, B; Ferenc, V; Kneidinger, M; Baumgartner, C; Mayerhofer, M; Gruze, A; Pickl, WF; Sillaber, C; Valent, P,期刊：Blood, 页码：5342-5351 , 文章类型： Article，,卷期：2009年114-26]
- Systemic mastocytosis (SM) is a myeloid neoplasm involving mast cells (MCs) and their progenitors. In most cases, neoplastic cells display the D816V-mutated variant of KIT. KIT D816V exhibits constitutive tyrosine kinase...
- AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations
[作者：Tang, JL; Hou, HA; Chen, CY; Liu, CY; Chou, WC; Tseng, MH; Huang, CF; Lee, FY; Liu, MC; Yao, M; Huang, SY; Ko, BS; Hsu, SC; Wu, SJ; Tsay, W; Chen, YC; Lin, LI; Tien, HF,期刊：Blood, 页码：5352-5361 , 文章类型： Article，,卷期：2009年114-26]
- Somatic mutation of the AML1/RUNX1(RUNX1) gene is seen in acute myeloid leukemia (AML) M0 subtype and in AML transformed from myelodysplastic syndrome, but the impact of this gene mutation on survival in AML patients rem...
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