- Therapeutic applications for novel non-hypercalcemic vitamin D receptor ligands
[作者:Choi, M; Makishima, M,期刊:Expert Opinion on Therapeutic Patents, 页码:593-606 , 文章类型: Review,,卷期:2009年19-5]
- Background: The active form of vitamin D-3, 1 alpha,25-dihydroxyvitamin D-3 (1,25(OH)(2)D-3), plays an important role in calcium homeostasis, cell differentiation, cell proliferation and immunity. A more complete underst...
- Microtubule stabilising agents for cancer chemotherapy
[作者:Zhao, Y; Fang, WS; Pors, K,期刊:Expert Opinion on Therapeutic Patents, 页码:607-622 , 文章类型: Review,,卷期:2009年19-5]
- Background: Microtubules are very important targets for cancer chemotherapy. During the past 15 years, three structurally diverse classes of microtubule stabilising agents (MSAs), namely, taxanes, epothilones and discode...
- New frontiers in cell-based immunotherapy of cancer
[作者:D'Elios, MM; Del Prete, G; Amedei, A,期刊:Expert Opinion on Therapeutic Patents, 页码:623-641 , 文章类型: Review,,卷期:2009年19-5]
- Background: Cancer remains one of the leading causes of death. Over the past decade, discovery of tumor antigens, as well as new findings in basic immunology, have led to novel opportunities for developing active immunot...
- Biodegradable 'intelligent' materials in response to chemical stimuli for biomedical applications
[作者:Ju, XJ; Xie, R; Yang, LH; Chu, LY,期刊:Expert Opinion on Therapeutic Patents, 页码:683-696 , 文章类型: Review,,卷期:2009年19-5]
- Background: Biodegradable stimuli-responsive materials, which exhibit large and sharp physical-chemical changes in response to small physical or chemical stimuli, are attracting increasing interests because of their pote...
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