- Bone Marrow Mononuclear Cells Have Neurovascular Tropism and Improve Diabetic Neuropathy
[作者:Kim, H; Park, JS; Choi, YJ; Kim, MO; Huh, YH; Kim, SW; Han, JW; Lee, J; Kim, S; Houge, MA; Ii, M; Yoon, YS,期刊:Stem Cells, 页码:1686-1696 , 文章类型: Article,,卷期:2009年27-7]
- Bone marrow-derived mononuclear cells (BMNCs) have been shown to effectively treat ischemic cardiovascular diseases. Because diabetic neuropathy (DN) is causally associated with impaired angiogenesis and deficiency of an...
- Stem Cell Transplant into Preimplantation Embryo Yields Myocardial Infarction-Resistant Adult Phenotype
[作者:Yamada, S; Nelson, TJ; Behfar, A; Crespo-Diaz, RJ; Fraidenraich, D; Terzic, A,期刊:Stem Cells, 页码:1697-1705 , 文章类型: Article,,卷期:2009年27-7]
- Stem cells are an emerging strategy for treatment of myocardial infarction, limited however to postinjury intervention. Preventive stem cell-based therapy to augment stress tolerance has yet to be considered for lifelong...
- Differentiation of a Highly Tumorigenic Basal Cell Compartment in Urothelial Carcinoma
[作者:He, XB; Marchionni, L; Hansel, DE; Yu, W; Sood, A; Yang, J; Parmigiani, G; Matsui, W; Berman, DM,期刊:Stem Cells, 页码:1487-1495 , 文章类型: Article,,卷期:2009年27-7]
- Highly tumorigenic cancer cell (HTC) populations have been identified for a variety of solid tumors and assigned stem cell properties. Strategies for identifying HTCs in solid tumors have been primarily empirical rather ...
- Embryonic Stem Cell-Derived Cardiomyogenesis: A Novel Role for Calreticulin as a Regulator
[作者:Papp, S; Dziak, E; Opas, M,期刊:Stem Cells, 页码:1507-1515 , 文章类型: Article,,卷期:2009年27-7]
- A role for calreticulin, an endoplasmic reticulum (ER)-resident, Ca2+-binding chaperone, has recently emerged in the context of cardiomyogenesis. We previously proposed calreticulin to be a novel cardiac fetal gene, beca...
- MicroRNA 92b Controls the G1/S Checkpoint Gene p57 in Human Embryonic Stem Cells
[作者:Sengupta, S; Nie, J; Wagner, RJ; Yang, CH; Stewart, R; Thomson, JA,期刊:Stem Cells, 页码:1524-1528 , 文章类型: Article,,卷期:2009年27-7]
- Human embryonic stem (ES) cells exhibit a shorter G(1) cell cycle phase than most somatic cells. Here, we examine the role of an abundant, human ES cell-enriched microRNA, miR-92b, in cell cycle distribution. Inhibition ...
- ES Cell Cycle Progression and Differentiation Require the Action of the Histone Methyltransferase Dot1L
[作者:Barry, ER; Krueger, W; Jakuba, CM; Veilleux, E; Ambrosi, DJ; Nelson, CE; Rasmussen, TP,期刊:Stem Cells, 页码:1538-1547 , 文章类型: Article,,卷期:2009年27-7]
- Mouse embryonic stem cells (ESCs) proliferate with rapid cell cycle kinetics but without loss of pluripotency. The histone methyltransferase Dot1L is responsible for methylation of histone H3 at lysine 79 (H3K79me). We i...
- Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging
[作者:Wang, H; Cao, F; De, A; Cao, Y; Contag, C; Gambhir, SS; Wu, JC; Chen, XY,期刊:Stem Cells, 页码:1548-1558 , 文章类型: Article,,卷期:2009年27-7]
- The objective of the study was to track the distribution and differentiation of mesenchymal stem cells (MSCs) in tumor-bearing mice. The 4T1 murine breast cancer cells were labeled with renilla luciferase-monomeric red f...
- Maintenance of Undifferentiated State and Self-Renewal of Embryonic Neural Stem Cells by Polycomb Protein Ring1B
[作者:Roman-Trufero, M; Mendez-Gomez, HR; Perez, C; Hijikata, A; Fujimura, Y; Endo, T; Koseki, H; Vicario-Abejon, C; Vidal, M,期刊:Stem Cells, 页码:1559-1570 , 文章类型: Article,,卷期:2009年27-7]
- Cell lineages generated during development and tissue maintenance are derived from self-renewing stem cells by differentiation of their committed progeny. Recent studies suggest that epigenetic mechanisms, and in particu...
- Murine "Cardiospheres'' Are Not a Source of Stem Cells with Cardiomyogenic Potential
[作者:Andersen, DC; Andersen, P; Schneider, M; Jensen, HB; Sheikh, SP,期刊:Stem Cells, 页码:1571-1581 , 文章类型: Article,,卷期:2009年27-7]
- Recent remarkable studies have reported that clonogenic putative cardiac stem cells (CSCs) with cardiomyogenic potential migrate from heart tissue biopsies during ex vivo culture, and that these CSCs self-organize into s...
- Bioluminescence Imaging of Olig2-Neural Stem Cells Reveals Improved Engraftment in a Demyelination Mouse Model
[作者:Sher, F; van Dam, G; Boddeke, E; Copray, S,期刊:Stem Cells, 页码:1582-1591 , 文章类型: Article,,卷期:2009年27-7]
- A major issue in the potential application of neural stem cell (NSC)-based cell replacement therapy for demyelinating diseases is the question of the survival, functional behavior, and stability of implanted NSC-derived ...
- Embryonic Stem Cells and Mammary Luminal Progenitors Directly Sense and Respond to Microbial Products
[作者:Lee, SH; Hong, BX; Sharabi, A; Huang, XF; Chen, SY,期刊:Stem Cells, 页码:1604-1615 , 文章类型: Article,,卷期:2009年27-7]
- Stem cells are normally maintained in a quiescent state and proliferate only under certain conditions; however, little is known about the biological stimuli that initiate the proliferation and differentiation of stem cel...
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