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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共46条记录   Cancer Prevention: From 1727 to Milestones of the Past 100 Years [作者：Lippman, SM; Hawk, ET,期刊：Cancer research, 页码：5269-5284 , 文章类型： Review，,卷期：2009年69-13] The rich, multidisciplinary history of cancer prevention recounted here begins with surgical and workplace recommendations of the 1700s and ends with 2009 results of the enormous (35,535 men) Selenium and Vitamin E [pros... Lessons from an Aggressive Cancer: Evolutionary Dynamics in Esophageal Carcinoma [作者：Klein, CA; Stoecklein, NH,期刊：Cancer research, 页码：5285-5288 , 文章类型： Review，,卷期：2009年69-13] Rapid progression to metastatic disease and an intrinsic resistance to any type of systemic therapy are hallmarks of aggressive solid cancers. The molecular basis for this phenotype is not clear. A detailed study of the ... Aneuploidy: Cancer's Fatal Flaw? [作者：Williams, BR; Amon, A,期刊：Cancer research, 页码：5289-5291 , 文章类型： Review，,卷期：2009年69-13] Aneuploidy is a characteristic of cancer, with greater than 90% of all solid tumors in humans carrying an aberrant karyotype. Yet, whether or how this condition contributes to tumorigenesis is not understood. Here we sum... T-Regulatory Cells Shift from a Protective Anti-inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis [作者：Gounaris, E; Blatner, NR; Dennis, K; Magnusson, F; Gurish, MF; Strom, TB; Beckhove, P; Gounari, F; Khazaie, K,期刊：Cancer research, 页码：5490-5497 , 文章类型： Article，,卷期：2009年69-13] T-regulatory (Treg) cells play a major role in cancer by suppressing protective antitumor immune responses. A series of observations (from a single laboratory) suggest that Treg cells are protective in cancer by virtue o... Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase-Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer [作者：Qian, F; Villella, J; Wallace, PK; Mhawech-Fauceglia, P; Tario, JD; Andrews, C; Matsuzaki, J; Valmori, D; Ayyoub, M; Frederick, PJ; Beck, A; Liao, JQ; Cheney, R; Moysich, K; Lele, S; Shrikant, P; Old, LJ; Odunsi, K,期刊：Cancer research, 页码：5498-5504 , 文章类型： Article，,卷期：2009年69-13] It has been reported that levo-l-methyl tryptophan (L-1MT) can block indoleamine-2,3-dioxygenase (IDO) expressed by human dendritic cells (DC), whereas dextro-l-methyl tryptophan (D-1MT) is inefficient. However, whether ... Expression of WSX1 in Tumors Sensitizes IL-27 Signaling-independent Natural Killer Cell Surveillance [作者：Dibra, D; Cutrera, JJ; Xia, XQ; Birkenbach, MP; Li, SL,期刊：Cancer research, 页码：5505-5513 , 文章类型： Article，,卷期：2009年69-13] It is well known that the interleukin (IL)-27 receptor WSX1 is expressed in immune cells and induces an IL-27-dependent immune response. Opposing this conventional dogma, this study reveals a much higher level of WSX1 ex... MDA-MB-435 and M14 Cell Lines: Identical but not M14 Melanoma? [作者：Chambers, AF,期刊：Cancer research, 页码：5292-5293 , 文章类型： Article，,卷期：2009年69-13] A controversy has arisen over the past several years about the true origin of the human MDA-MB-435 cell line. Originally described as a human breast cancer cell line, subsequent expression array studies instead suggested... The Liver Is a Site for Tumor-induced Myeloid-Derived Suppressor Cell Accumulation and Immunosuppression [作者：Ilkovitch, D; Lopez, DM,期刊：Cancer research, 页码：5514-5521 , 文章类型： Article，,卷期：2009年69-13] Tumor-induced immunosuppression plays a key role in tumor evasion of the immune system. A key cell population recognized as myeloid-derived suppressor cells (MDSC) contributes and helps orchestrate this immunosuppression... A "Vascular Normalization Index" as Potential Mechanistic Biomarker to Predict Survival after a Single Dose of Cediranib in Recurrent Glioblastoma Patients [作者：Sorensen, AG; Batchelor, TT; Zhang, WT; Chen, PJ; Yeo, P; Wang, MY; Jennings, D; Wen, PY; Lahdenranta, J; Ancukiewicz, M; di Tomaso, E; Duda, DG; Jain, RK,期刊：Cancer research, 页码：5296-5300 , 文章类型： Article，,卷期：2009年69-13] Early imaging or blood biomarkers of tumor response are desperately needed to customize antiangiogenic therapy for cancer patients. Anti-vascular endothelial growth factor (VEGF) therapy can "normalize" brain tumor vascu... Malignant B Cells Skew the Balance of Regulatory T Cells and T(H)17 Cells in B-Cell Non-Hodgkin's Lymphoma [作者：Yang, ZZ; Novak, AJ; Ziesmer, SC; Witzig, TE; Ansell, SM,期刊：Cancer research, 页码：5522-5530 , 文章类型： Article，,卷期：2009年69-13] Using biopsy specimens from patients with B-cell non-Hodgkin's lymphoma, we observed a significantly low frequency of T(H)17 cells, including several samples with no detectable amount of interleukin (IL)-17-producing cel... Microcephalin Regulates BRCA2 and Rad51-Associated DNA Double-Strand Break Repair [作者：Wu, XL; Mondal, G; Wang, XS; Wu, JM; Yang, L; Pankratz, VS; Rowley, M; Couch, FJ,期刊：Cancer research, 页码：5531-5536 , 文章类型： Article，,卷期：2009年69-13] Microcephalin (MCPH1) is a BRCA1 COOH terminal (BRCT) domain containing protein involved in the cellular response to DNA damage that has been implicated in autosomal recessive primary microcephaly. MCPH1 is recruited to ... Functional Phosphodiesterase 11A Mutations May Modify the Risk of Familial and Bilateral Testicular Germ Cell Tumors [作者：Horvath, A; Korde, L; Greene, MH; Libe, R; Osorio, P; Faucz, FR; Raffin-Sanson, ML; Tsang, KM; Drori-Herishanu, L; Patronas, Y; Remmers, EF; Nikita, ME; Moran, J; Greene, J; Nesterova, M; Merino, M; Bertherat, J; Stratakis, CA,期刊：Cancer research, 页码：5301-5306 , 文章类型： Article，,卷期：2009年69-13] Inactivating germline mutations in phosphodiesterase 11A (PDE11A) have been implicated in adrenal tumor susceptibility. PDE11A is highly expressed in endocrine steroidogenic tissues, especially the testis, and mice with ... Bortezomib Alone or in Combination with the Histone Deacetylase Inhibitor JNJ-26481585: Effect on Myeloma Bone Disease in the 5T2MM Murine Model of Myeloma [作者：Deleu, S; Lemaire, M; Arts, J; Menu, E; Van Valckenborgh, E; Broek, IV; De Raeve, H; Coulton, L; Van Camp, B; Croucher, P; Vanderkerken, K,期刊：Cancer research, 页码：5307-5311 , 文章类型： Article，,卷期：2009年69-13] The proteasome inhibitor bortezomib (Velcade) is currently approved as second-line treatment of multiple myeloma (MM). MM-related bone disease is one of the most debilitating complications of MM. Besides supportive care ... Plasminogen Kringle 5 Induces Apoptosis of Brain Microvessel Endothelial Cells: Sensitization by Radiation and Requirement for GRP78 and LRP1 [作者：McFarland, BC; Stewart, J; Hamza, A; Nordal, R; Davidson, DJ; Henkin, J; Gladson, CL,期刊：Cancer research, 页码：5537-5545 , 文章类型： Article，,卷期：2009年69-13] Recombinant plasminogen kringle 5 (rK5) has been shown to induce apoptosis of dermal microvessel endothelial cells (MvEC) in a mariner that requires glucose-regulated protein 78 (GRP78). As we are interested in antian... ADAM23 Negatively Modulates alpha(v)beta(3) Integrin Activation during Metastasis [作者：Verbisck, NV; Costa, ET; Costa, FF; Cavalher, FP; Costa, MDM; Muras, A; Paixao, VA; Moura, R; Granato, MF; Ierardi, DF; Machado, T; Melo, F; Ribeiro, KB; Cunha, IW; Lima, VCC; Maciel, MD; Carvalho, AL; Soares, FF; Zanata, S; Sogayar, MC; Chammas, R; Camargo, AA,期刊：Cancer research, 页码：5546-5552 , 文章类型： Article，,卷期：2009年69-13] The ADAM23 gene is frequently silenced in different types of tumors, and, in breast tumors, silencing is correlated with tumor progression, suggesting that it might be associated with the acquisition of a metastatic phen... Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes [作者：Pinnix, CC; Lee, JT; Liu, ZJ; McDaid, R; Balint, K; Beverly, LJ; Brafford, PA; Xiao, M; Himes, B; Zabierowski, SE; Yashiro-Ohtani, Y; Nathanson, KL; Bengston, A; Pollock, PM; Weeraratna, AT; Nickoloff, BJ; Pear, WS; Capobianco, AJ; Herlyn, M,期刊：Cancer research, 页码：5312-5320 , 文章类型： Article，,卷期：2009年69-13] The importance of mitogen-activated protein kinase signaling in melanoma is underscored by the prevalence of activating mutations in N-Ras and B-Raf, yet clinical development of inhibitors of this pathway has been largel...