- Host-Derived Tumor Endothelial Marker 8 Promotes the Growth of Melanoma
[作者：Cullen, M; Seaman, S; Chaudhary, A; Yang, MY; Hilton, MB; Logsdon, D; Haines, DC; Tessarollo, L; St Croix, B,期刊：Cancer research, 页码：6021-6026 , 文章类型： Article，,卷期：2009年69-15]
- Tumor endothelial marker 8 (TEM8) was initially identified as a gene overexpressed in the vasculature of human tumors and was subsequently identified as an anthrax toxin receptor. To assess the functional role of TEM8, w...
- Reactivation of Androgen Receptor-Regulated TMPRSS2:ERG Gfene Expression in Castration-Resistant Prostate Cancer
[作者：Cai, CM; Wang, HY; Xu, YY; Chen, SY; Balk, SP,期刊：Cancer research, 页码：6027-6032 , 文章类型： Article，,卷期：2009年69-15]
- It seems clear that androgen receptor (AR)-regulated expression of the TMPRSS2:ERG fusion gene plays an early role in prostate cancer (PC) development or progression, but the extent to which TMPRSS2:ERG is down-regulated...
- Differentiation of Lung Adenocarcinoma, Pleural Mesothelioma, and Nonmalignant Pulmonary Tissues Using DNA Methylation Profiles
[作者：Christensen, BC; Marsit, CJ; Houseman, EA; Godleski, JJ; Longacker, JL; Zheng, SC; Yeh, RF; Wrensch, MR; Wiemels, JL; Karagas, MR; Bueno, R; Sugarbaker, DJ; Nelson, HH; Wiencke, JK; Kelsey, KT,期刊：Cancer research, 页码：6315-6321 , 文章类型： Article，,卷期：2009年69-15]
- Pathologic differentiation of tissue of origin in tumors found in the lung can be challenging, with differentiation of mesothelioma and lung adenocarcinoma emblematic of this problem. Indeed, proper classification is ess...
- Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation
[作者：Mohammad, HP; Cai, Y; McGarvey, KM; Easwaran, H; Van Neste, L; Ohm, JE; O'Hagan, HM; Baylin, SB,期刊：Cancer research, 页码：6322-6330 , 文章类型： Article，,卷期：2009年69-15]
- Epigenetic silencing of genes in association with aberrant promoter DNA hypermethylation has emerged as a significant mechanism in the development of human cancers. Such genes are also often targets of the polycomb group...
- Vascular Endothelial Growth Factor-C Protects Prostate Cancer Cells from Oxidative Stress by the Activation of Mammalian Target of Rapamycin Complex-2 and AKT-1
[作者：Muders, MH; Zhang, HY; Wang, E; Tindall, DJ; Datta, K,期刊：Cancer research, 页码：6042-6048 , 文章类型： Article，,卷期：2009年69-15]
- Recurrence and subsequent metastatic transformation of cancer develops from a subset of malignant cells, which show the ability to resist stress and to adopt to a changing microenvironment. These tumor cells have distinc...
- The G Protein-Coupled Receptor 87 Is Necessary for p53-Dependent Cell Survival in Response to Genotoxic Stress
[作者：Zhang, YH; Qian, YJ; Lu, WF; Chen, XB,期刊：Cancer research, 页码：6049-6056 , 文章类型： Article，,卷期：2009年69-15]
- p53 regulates an array of target genes, which mediates p53 tumor suppression by inducing cell cycle arrest, apoptosis, and cell survival. G protein-coupled receptors belong to a superfamily of cell surface molecules and ...
- Overexpression of Platelet-Derived Growth Factor-BB Increases Tumor Pericyte Content via Stromal-Derived Factor-1 alpha/CXCR4 Axis
[作者：Song, N; Huang, YH; Shi, HB; Yuan, SP; Ding, YP; Song, XM; Fu, Y; Luo, YZ,期刊：Cancer research, 页码：6057-6064 , 文章类型： Article，,卷期：2009年69-15]
- Platelet-derived growth factor-BB (PDGF-BB) is a well-characterized growth factor displaying potent biological effects on angiogenesis. Recent studies reveal that overexpression of PDGF-BB within tumors results in increa...
- CCL5-Mediated Endogenous Antitumor Immunity Elicited by Adoptively Transferred Lymphocytes and Dendritic Cell Depletion
[作者：Nesbeth, Y; Scarlett, U; Cubillos-Ruiz, J; Martinez, D; Engle, X; Turk, MJ; Conejo-Garcia, JR,期刊：Cancer research, 页码：6331-6338 , 文章类型： Article，,卷期：2009年69-15]
- Adoptive transfer of antitumor T cells is a promisingly effective therapy for various cancers, but its effect on endogenous antitumor immune mechanisms remains largely unknown. Here, we show that the administration of na...
- Fibulin-5 Suppresses Lung Cancer Invasion by Inhibiting Matrix Metalloproteinase-7 Expression
[作者：Yue, W; Sun, QH; Landreneau, R; Wu, CY; Siegfried, JM; Yu, J; Zhang, L,期刊：Cancer research, 页码：6339-6346 , 文章类型： Article，,卷期：2009年69-15]
- The high mortality rate of lung cancer is largely due to the spread of disease to other organs. However, the molecular changes driving lung cancer invasion and metastasis remain unclear. In this study, we identified fibu...
- The Wnt Target Jagged-1 Mediates the Activation of Notch Signaling by Progastrin in Human Colorectal Cancer Cells
[作者：Pannequin, J; Bonnans, C; Delaunay, N; Ryan, J; Bourgaux, JF; Joubert, D; Hollande, F,期刊：Cancer research, 页码：6065-6073 , 文章类型： Article，,卷期：2009年69-15]
- The Whit and Notch signaling pathways are both abnormally activated in colorectal cancer (CRC). We recently showed that progastrin depletion inhibited Writ signaling and increased goblet cell differentiation of CRC cells...
- Loss of Histone Deacetylase 4 Causes Segregation Defects during Mitosis of p53-Deficient Human Tumor Cells
[作者：Cadot, B; Brunetti, M; Coppari, S; Fedeli, S; de Rinaldis, E; Dello Russo, C; Gallinari, P; De Francesco, R; Steinkuhler, C; Filocamo, G,期刊：Cancer research, 页码：6074-6082 , 文章类型： Article，,卷期：2009年69-15]
- We investigated the role of histone deacetylase 4 (HDAC4) using RNA interference (RNAi) and knockout cells to specifically address its role in cell cycle progression in tumor and normal cells. Ablation of HDAC4 led to gr...
- Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling
[作者：Qayum, N; Muschel, RJ; Im, JH; Balathasan, L; Koch, CJ; Patel, S; McKenna, WG; Bernhard, EJ,期刊：Cancer research, 页码：6347-6354 , 文章类型： Article，,卷期：2009年69-15]
- Many inhibitors of the epidermal growth factor receptor (EGFR)-RAS-phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway are in clinical use or under development for cancer therapy. Here, we show that treatment of m...
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