- Nuclear Factor-KB-Mediated Transforming Growth Factor-beta-Induced Expression of Vimentin Is an Independent Predictor of Biochemical Recurrence after Radical Prostatectomy
[作者：Zhang, Q; Helfand, BT; Jang, TL; Zhu, LHJ; Chen, L; Yang, XMJ; Kozlowski, J; Smith, N; Kundu, SD; Yang, GY; Raji, AA; Javonovic, B; Pins, M; Lindholm, P; Guo, YL; Catalona, WJ; Lee, C,期刊：Clinical Cancer Research, 页码：3557-3567 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Transforming growth factor-beta (TGF-beta)-mediated epithelial-to-mesenchymal transition (EMT) has been shown to occur in some cancers; however, the pathway remains controversial and varies with different cancer...
- Prognostic Value of Akt-1 in Human Prostate Cancer: A Computerized Quantitative Assessment with Quantum Dot Technology
[作者：Li, RL; Dai, H; Wheeler, TM; Sayeeduddin, M; Scardino, PT; Frolov, A; Ayala, GE,期刊：Clinical Cancer Research, 页码：3568-3573 , 文章类型： Article，,卷期：2009年15-10]
- Background: Akt/protein kinase B signaling pathway has been implicated in tumorigenesis and progression. Previous studies showed the predictive potential of p-Akt-1, but total Akt-1 could provide more reliable informatio...
- Immunodeficient Mouse Strains Display Marked Variability in Growth of Human Melanoma Lung Metastases
[作者：Carreno, BM; Garbow, JR; Kolar, GR; Jackson, EN; Engelbach, JA; Becker-Hapak, M; Carayannopoulos, LN; Piwnica-Worms, D; Linette, GP,期刊：Clinical Cancer Research, 页码：3277-3286 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Immunodeficient mice serve as critical hosts for transplantation of xenogeneic cells for in vivo analysis of various biological processes. Because investigators typically select one or two immunodeficient mouse ...
- Aberrant Splicing of Hugl-1 Is Associated with Hepatocellular Carcinoma Progression
[作者：Lu, XF; Feng, XJ; Man, XB; Yang, G; Tang, L; Du, D; Zhang, F; Yuan, HX; Huang, Q; Zhang, Z; Liu, YK; Strand, D; Chen, ZJ,期刊：Clinical Cancer Research, 页码：3287-3296 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Lethal giant larvae functions as a cell polarity regulator and a tumor suppressor in Drosophila. Its evolutionary conservation implies a tumor suppressor role for its human homologue, Hugl-1. The aims of this st...
- A Phase I Study of the P-Glycoprotein Antagonist Tariquidar in Combination with Vinorelbine
[作者：Abraham, J; Edgerly, M; Wilson, R; Chen, C; Rutt, A; Bakke, S; Robey, R; Dwyer, A; Goldspiel, B; Balis, F; Van Tellingen, O; Bates, SE; Fojo, T,期刊：Clinical Cancer Research, 页码：3574-3582 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: P-glycoprotein (Pgp) antagonists have had unpredictable pharmacokinetic interactions requiring reductions of chemotherapy. We report a phase I study using tariquidar (XR9576), a potent Pgp antagonist, in combina...
- Correlation between DNA Repair Capacity in Lymphocytes and Acute Side Effects to Skin during Radiotherapy in Nasopharyngeal Cancer Patients (vol 11, pg 5140, 2005)
[作者：Wang, WD; Chen, ZT; Li, DZ; Cao, ZH; Pu, P; Sun, SL; Shen, XP,期刊：Clinical Cancer Research, 页码：3642-3642 , 文章类型： Correction，,卷期：2009年15-10]
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- Loss of VHL and Hypoxia Provokes PAX2 Up-Regulation in Clear Cell Renal Cell Carcinoma
[作者：Luu, VD; Boysen, G; Struckmann, K; Casagrande, S; von Teichman, A; Wild, PJ; Sulser, T; Schraml, P; Moch, H,期刊：Clinical Cancer Research, 页码：3297-3304 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: The paired box gene 2, PAX2, encodes for a transcription factor that is up-regulated during nephrogenesis and becomes silenced in mature epithelium of the glomeruli, the proximal, and distal tubules. Reactivatio...
- Chromosomal Instability and Copy Number Alterations in Barrett's Esophagus and Esophageal Adenocarcinoma
[作者：Paulson, TG; Maley, CC; Li, XH; Li, H; Sanchez, CA; Chao, DL; Odze, RD; Vaughan, TL; Blount, PL; Reid, BJ,期刊：Clinical Cancer Research, 页码：3305-3314 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Chromosomal instability, as assessed by many techniques, including DNA content aneuploidy, loss of heterozygosity, and comparative genomic hybridization, has consistently been reported to be common in cancer and...
- A Vasculature-Targeting Regimen of Preoperative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer: Impact on Angiogenic Biomarkers
[作者：Baar, J; Silverman, P; Lyons, J; Fu, PF; Abdul-Karim, F; Ziats, N; Wasman, J; Hartman, P; Jesberger, J; Dumadag, L; Hohler, E; Leeming, R; Shenk, R; Chen, H; McCrae, K; Dowlati, A; Remick, SC; Overmoyer, B,期刊：Clinical Cancer Research, 页码：3583-3590 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Taxanes have effects on angiogenesis causing difficulties in separating biological effects of chemotherapy from those due to angiogenesis inhibitors. This randomized phase 11 trial was designed to evaluate the a...
- Phase I and Pharmacokinetic Study of Trabectedin as a 1- or 3-hour Infusion Weekly in Patients with Advanced Solid Malignancies
[作者：Forouzesh, B; Hidalgo, M; Chu, Q; Mita, A; Mita, M; Schwartz, G; Jimeno, J; Gomez, J; Alfaro, V; Lebedinsky, C; Zintl, P; Rowinsky, EK,期刊：Clinical Cancer Research, 页码：3591-3599 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: This study was designed to determine the safety, tolerability, and pharmacokinetics, and to seek preliminary evidence of anticancer activity of trabectedin, a novel marine-derived DNA minor grove binder, when ad...
- Analysis of ErbB Receptors in Pulmonary Carcinoid Tumors
[作者：Rickman, OB; Vohra, PK; Sanyal, B; Vrana, JA; Aubry, MC; Wigle, DA; Thomas, CF,期刊：Clinical Cancer Research, 页码：3315-3324 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: This study aimed to investigate the expression of the ErbB family of receptor tyrosine kinases in pulmonary typical carcinoid and atypical carcinoid tumors and to understand the role of epidermal growth factor r...
- Increased Frequency and Suppression by Regulatory T Cells in Patients with Acute Myelogenous Leukemia
[作者：Szczepanski, MJ; Szajnik, M; Czystowska, M; Mandapathil, M; Strauss, L; Welsh, A; Foon, KA; Whiteside, TL; Boyiadzis, M,期刊：Clinical Cancer Research, 页码：3325-3332 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Regulatory CD4(+)CD25(high)Foxp3(+) T cells (Treg) control peripheral immune tolerance. Patients with cancer, including those with hematologic malignancies, have elevated numbers of Treg in the peripheral circul...
- Baseline Vascular Endothelial Growth Factor Concentration as a Potential Predictive Marker of Benefit from Vandetanib in Non-Small Cell Lung Cancer
[作者：Hanrahan, EO; Ryan, AJ; Mann, H; Kennedy, SJ; Langmuir, P; Natale, RB; Herbst, RS; Johnson, BE; Heymach, JV,期刊：Clinical Cancer Research, 页码：3600-3609 , 文章类型： Article，,卷期：2009年15-10]
- Purpose: Vandetanib [vascular endothelial growth factor (VEGF) receptor/epidermal growth factor receptor/RET inhibitor] has shown improvements in progression-free survival (PFS) in advanced non-small cell lung cancer in ...
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