- Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model
[作者:Yoon, SH; Lee, JM; Cho, HI; Kim, EK; Kim, HS; Park, MY; Kim, TG,期刊:Cancer gene therapy, 页码:489-497 , 文章类型: Article,,卷期:2009年16-6]
- The current gene transfer technology for single chain (scFv)-based chimeric immune receptor (CIR) has relied on retrovirus and lentivirus vectors which require a long time to obtain sufficient number of transduced cells ...
- P53 and PTEN expression contribute to the inhibition of EGFR downstream signaling pathway by cetuximab
[作者:Bouali, S; Chretien, AS; Ramacci, C; Rouyer, M; Marchal, S; Galenne, T; Juin, P; Becuwe, P; Merlin, JL,期刊:Cancer gene therapy, 页码:498-507 , 文章类型: Article,,卷期:2009年16-6]
- Cetuximab (Erbitux) is an anti-epidermal growth factor receptor ( EGFR) monoclonal antibody whose activity is related to the inhibition of EGFR downstream signaling pathways. P53 and phosphatase and tensin homologue dele...
- Expression and function of the coxsackie and adenovirus receptor in Barrett's esophagus and associated neoplasia
[作者:Anders, M; Rosch, T; Kuster, K; Becker, I; Hofler, H; Stein, HJ; Meining, A; Wiedenmann, B; Sarbia, M,期刊:Cancer gene therapy, 页码:508-515 , 文章类型: Article,,卷期:2009年16-6]
- Cell surface presence of the coxsackie and adenovirus receptor (CAR) is considered a crucial prerequisite for the uptake of attenuated adenovirus. In cancers, however, a frequent loss of CAR has been noted potentially ha...
- Multitarget therapy of malignant cancers by the head-to-tail tandem array multiple shRNAs expression system
[作者:Cheng, TL; Teng, CF; Tsai, WH; Yeh, CW; Wu, MP; Hsu, HC; Hung, CF; Chang, WT,期刊:Cancer gene therapy, 页码:516-531 , 文章类型: Article,,卷期:2009年16-6]
- Coexpression of multiple shRNAs can simultaneously inhibit multiple genes or target multiple sites on a single gene. These approaches can be used for dissecting complex signaling pathways and even be applied to targeting...
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