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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共33条记录   Thoc1 Deficiency Compromises Gene Expression Necessary for Normal Testis Development in the Mouse [作者：Wang, XL; Chinnam, M; Wang, JM; Wang, YQ; Zhang, XJ; Marcon, E; Moens, P; Goodrich, DW,期刊：Molecular and Cellular Biology, 页码：2794-2803 , 文章类型： Article，,卷期：2009年29-10] Accumulating evidence suggests that regulation of RNA processing through an RNP-driven mechanism is important for coordinated gene expression. This hypothesis predicts that defects in RNP biogenesis will adversely affect... The p53 Tumor Suppressor Causes Congenital Malformations in Rpl24-Deficient Mice and Promotes Their Survival [作者：Barkic, M; Crnomarkovic, S; Grabusic, K; Bogetic, I; Panic, L; Tamarut, S; Cokaric, M; Jeric, I; Vidak, S; Volarevic, S,期刊：Molecular and Cellular Biology, 页码：2489-2504 , 文章类型： Article，,卷期：2009年29-10] Hypomorphic mutation in one allele of ribosomal protein l24 gene (Rpl24) is responsible for the Belly Spot and Tail (Bst) mouse, which suffers from defects of the eye, skeleton, and coat pigmentation. It has been hypothe... Multivalent Binding of the ETO Corepressor to E Proteins Facilitates Dual Repression Controls Targeting Chromatin and the Basal Transcription Machinery [作者：Guo, C; Hu, QD; Yan, CX; Zhang, JS,期刊：Molecular and Cellular Biology, 页码：2644-2657 , 文章类型： Article，,卷期：2009年29-10] E proteins are a family of helix-loop-helix transcription factors that play important roles in cell differentiation and homeostasis. They contain at least two activation domains, AD1 and AD2. ETO family proteins and the ... Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response [作者：Sun, Z; Chin, YE; Zhang, DD,期刊：Molecular and Cellular Biology, 页码：2658-2672 , 文章类型： Article，,卷期：2009年29-10] To maintain intracellular redox homeostasis, genes encoding many antioxidants and detoxification enzymes are transcriptionally upregulated upon deleterious oxidative stress through the cis antioxidant responsive elements... Dual Role of Cdc42 in Spindle Orientation Control of Adherent Cells [作者：Mitsushima, M; Toyoshima, F; Nishida, E,期刊：Molecular and Cellular Biology, 页码：2816-2827 , 文章类型： Article，,卷期：2009年29-10] The spindle orientation is regulated by the interaction of astral microtubules with the cell cortex. We have previously shown that spindles in nonpolarized adherent cells are oriented parallel to the substratum by an act... Zinc Finger Protein Zbtb20 Is Essential for Postnatal Survival and Glucose Homeostasis [作者：Sutherland, APR; Zhang, H; Zhang, Y; Michaud, M; Xie, ZF; Patti, ME; Grusby, MJ; Zhang, WJ,期刊：Molecular and Cellular Biology, 页码：2804-2815 , 文章类型： Article，,卷期：2009年29-10] Zbtb20 is a member of the POK family of proteins, which function primarily as transcriptional repressors via interactions mediated by their conserved C2H2 Kruppel type zinc finger and BTB/POZ domains. To define the funct... miR-181a Regulates Cap-Dependent Translation of p27(kip1) mRNA in Myeloid Cells [作者：Cuesta, R; Martinez-Sanchez, A; Gebauer, F,期刊：Molecular and Cellular Biology, 页码：2841-2851 , 文章类型： Article，,卷期：2009年29-10] p27(kip1) (p27) is a cell cycle inhibitor and tumor suppressor whose expression is tightly regulated in the cell. Translational control of p27 mRNA has emerged as a prominent mechanism to regulate p27 expression during d... Spi-1 and Fli-1 Directly Activate Common Target Genes Involved in Ribosome Biogenesis in Friend Erythroleukemic Cells [作者：Juban, G; Giraud, G; Guyot, B; Belin, S; Diaz, JJ; Starck, J; Guillouf, C; Moreau-Gachelin, F; Morle, F,期刊：Molecular and Cellular Biology, 页码：2852-2864 , 文章类型： Article，,卷期：2009年29-10] Spi-1 and Fli-1 are ETS transcription factors recurrently deregulated in mouse erythroleukemia induced by Friend viruses. Since they share the same core DNA binding site, we investigated whether they may contribute to er... Tyrosine Phosphorylation of Grb2: Role in Prolactin/Epidermal Growth Factor Cross Talk in Mammary Epithelial Cell Growth and Differentiation [作者：Haines, E; Minoo, P; Feng, Z; Resalatpanah, N; Nie, XM; Campiglio, M; Alvarez, L; Cocolakis, E; Ridha, M; Di Fulvio, M; Gomez-Cambronero, J; Lebrun, JJ; Ali, S,期刊：Molecular and Cellular Biology, 页码：2505-2520 , 文章类型： Article，,卷期：2009年29-10] Characterizing mechanisms regulating mammary cell growth and differentiation is vital, as they may contribute to breast carcinogenesis. Here, we examine a cross talk mechanism(s) downstream of prolactin (PRL), a primary ... Direct Spatial Control of Epac1 by Cyclic AMP [作者：Ponsioen, B; Gloerich, M; Ritsma, L; Rehmann, H; Bos, JL; Jalink, K,期刊：Molecular and Cellular Biology, 页码：2521-2531 , 文章类型： Article，,卷期：2009年29-10] Epac1 is a guanine nucleotide exchange factor (GEF) for the small G protein Rap and is directly activated by cyclic AMP (cAMP). Upon cAMP binding, Epac1 undergoes a conformational change that allows the interaction of it... Mutational Analysis of the Sir3 BAH Domain Reveals Multiple Points of Interaction with Nucleosomes [作者：Sampath, V; Yuan, P; Wang, IX; Prugar, E; van Leeuwen, F; Sternglanz, R,期刊：Molecular and Cellular Biology, 页码：2532-2545 , 文章类型： Article，,卷期：2009年29-10] Sir3, a component of the transcriptional silencing complex in the yeast Saccharomyces cerevisiae, has an N-terminal BAH domain that is crucial for the protein's silencing function. Previous work has shown that the N-term... H2AX Is Required for Cell Cycle Arrest via the p53/p21 Pathway [作者：Fragkos, M; Jurvansuu, J; Beard, P,期刊：Molecular and Cellular Biology, 页码：2828-2840 , 文章类型： Article，,卷期：2009年29-10] Phosphorylation of H2AX (gamma H2AX) is an early sign of DNA damage induced by replication stalling. However, the role of H2AX in the repair of this type of DNA damage is still unclear. In this study, we used an inactiva... Regulation of p53 by TopBP1: a Potential Mechanism for p53 Inactivation in Cancer [作者：Liu, K; Bellam, N; Lin, HY; Wang, B; Stockard, CR; Grizzle, WE; Lin, WC,期刊：Molecular and Cellular Biology, 页码：2673-2693 , 文章类型： Article，,卷期：2009年29-10] Proper control of the G(1)/S checkpoint is essential for normal proliferation. The activity of p53 must be kept at a very low level under unstressed conditions to allow growth. Here we provide evidence supporting a cruci... ADAM9 Is Involved in Pathological Retinal Neovascularization [作者：Guaiquil, V; Swendeman, S; Yoshida, T; Chavala, S; Campochiaro, PA; Blobel, CP,期刊：Molecular and Cellular Biology, 页码：2694-2703 , 文章类型： Article，,卷期：2009年29-10] Pathological ocular neovascularization, caused by diabetic retinopathy, age-related macular degeneration, or retinopathy of prematurity, is a leading cause of blindness, yet much remains to be learned about its underlyin... Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)-and Ribosomal Protein S6K-Mediated Signals [作者：Kroczynska, B; Kaur, S; Katsoulidis, E; Majchrzak-Kita, B; Sassano, A; Kozma, SC; Fish, EN; Platanias, LC,期刊：Molecular and Cellular Biology, 页码：2865-2875 , 文章类型： Article，,卷期：2009年29-10] Although the roles of Jak-Stat pathways in type I and II interferon (IFN)-dependent transcriptional regulation are well established, the precise mechanisms of mRNA translation for IFN-sensitive genes remain to be defined... Normal Function of the Yeast TOR Pathway Requires the Type 2C Protein Phosphatase Ptc1 [作者：Gonzalez, A; Ruiz, A; Casamayor, A; Arino, J,期刊：Molecular and Cellular Biology, 页码：2876-2888 , 文章类型： Article，,卷期：2009年29-10] Yeast ptc1 mutants are rapamycin and caffeine sensitive, suggesting a functional connection between Ptc1 and the TOR pathway that is not shared by most members of the type 2C phosphatase family. Genome-wide profiling rev...