- Entamoeba histolytica EhDEAD1 is a conserved DEAD-box RNA helicase with ATPase and ATP-dependent RNA unwinding activities
[作者:Lopez-Camarillo, C; Garcia-Hernandez, MD; Marchat, LA; Luna-Arias, JP; de la Cruz, OH; Mendoza, L; Orozco, E,期刊:Gene, 页码:19-31 , 文章类型: Article,,卷期:2008年414-1-2]
- RNA helicases are widely conserved key enzymes that perform multiple functions in RNA metabolism. Here, we present the cloning, expression and functional characterization of the EhDEAD1 RNA helicase in the protozoan para...
- The role of the Saccharomyces cerevisiae Cdc7-Dbf4 complex in the replication checkpoint
[作者:Ogi, H; Wang, CZ; Nakal, W; Kawasaki, Y; Masumoto, H,期刊:Gene, 页码:32-40 , 文章类型: Article,,卷期:2008年414-1-2]
- The Cdc7-Dbf4 complex is a conserved serine/threonine protein kinase essential for the initiation of eukaryotic DNA replication. Although an mcm5-bob1 mutation bypasses lethality conferred by mutations in CDC7 or DBF4, t...
- Global gene expression analysis reveals specific and redundant roles for H1 variants, H1c and H1(0), in gene expression regulation
[作者:Bhan, S; May, W; Warren, SL; Sittman, DB,期刊:Gene, 页码:10-18 , 文章类型: Article,,卷期:2008年414-1-2]
- In mammals, the functional significance of the presence of evolutionarily conserved, multiple non-allelic H1 variants remains unclear. We used a unique overproduction approach coupled with cell cycle synchronization and ...
- Succinate dehydrogenase gene arrangement and expression in Anaplasma phagocytophilum
[作者:Massung, RF; Hiratzka, SL; Brayton, KA; Palmer, GH; Lee, KN,期刊:Gene, 页码:41-48 , 文章类型: Article,,卷期:2008年414-1-2]
- DNA sequencing of the region directly downstream of the Anaplasma phagocytophilum (strain MRK) 16S rRNA gene identified homologues of sdhC and sdhD; however, further sequencing by gene walking failed to identify addition...
- A new technique for activation tagging in Arabidopsis
[作者:Pogorelko, GV; Fursova, OV; Ogarkova, OA; Tarasov, VA,期刊:Gene, 页码:67-75 , 文章类型: Article,,卷期:2008年414-1-2]
- We have created and applied to Arabidopsis thaliana a new system of two vectors. The first vector (pEnLox) is intended for activation tagging and contains a multimerized transcriptional enhancer from the cauliflower mosa...
- In silico strategy for detection of target candidates for antibody therapy of solid tumors
[作者:Helftenbein, G; Koslowski, M; Dhaene, K; Seitz, G; Sahin, U; Tuereci, O,期刊:Gene, 页码:76-84 , 文章类型: Article,,卷期:2008年414-1-2]
- In contrast to earlier attempts for the identification of target candidates suitable for monoclonal antibody (mAb) based cancer therapies we concentrated on highly selective lineage-specific genes additionally preserved ...
- Positive regulation of promoter activity of human 3-phosphoglycerate dehydrogenase (PHGDH) gene is mediated by transcription factors Sp1 and NF-Y
[作者:Jun, DY; Park, HS; Lee, JY; Baek, JY; Park, HK; Fukui, K; Kim, YH,期刊:Gene, 页码:106-114 , 文章类型: Article,,卷期:2008年414-1-2]
- The PHGDH gene encodes the 3-phosphoglycerate dehydrogenase that catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxy pyruvate for the phosphorylated pathway of serine biosynthesis. To understand transcri...
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