- A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma
[作者：Ndozangue-Touriguine, O; Sebbagh, M; Merino, D; Micheau, O; Bertoglio, J; Breard, J,期刊：Oncogene, 页码：6012-6022 , 文章类型： Article，,卷期：2008年27-46]
- A pair of isogenic colon carcinoma cells, SW480 and 620, was used to investigate the mechanisms of acquired tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistance during tumour progression. Whereas p...
- v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins
[作者：Sobue, S; Murakami, M; Banno, Y; Ito, H; Kimura, A; Gao, S; Furuhata, A; Takagi, A; Kojima, T; Suzuki, M; Nozawa, Y; Murate, T,期刊：Oncogene, 页码：6023-6033 , 文章类型： Article，,卷期：2008年27-46]
- Sphingosine kinase 1 (SPHK1) is overexpressed in solid tumors and leukemia. However, the mechanism of SPHK1 overexpression by oncogenes has not been defined. We found that v-Src-transformed NIH3T3 cells showed a high SPH...
- N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1(NLRR1) gene in neuroblastoma
[作者：Hossain, MS; Ozaki, T; Wang, H; Nakagawa, A; Takenobu, H; Ohira, M; Kamijo, T; Nakagawara, A,期刊：Oncogene, 页码：6075-6082 , 文章类型： Article，,卷期：2008年27-46]
- Neuronal leucine-rich repeat protein-1(NLRR1) gene encodes a type I transmembrane protein with unknown function. We have previously described that NLRR1 gene is highly expressed in unfavorable neuroblastomas as compared ...
- DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells
[作者：Garcia-Aragoncillo, E; Carrillo, J; Lalli, E; Agra, N; Gomez-Lopez, G; Pestana, A; Alonso, J,期刊：Oncogene, 页码：6034-6043 , 文章类型： Article，,卷期：2008年27-46]
- The molecular hallmark of the Ewing's family of tumors is the presence of balanced chromosomal translocations, leading to the formation of chimerical transcription factors (that is, EWS/FLI1) that play a pivotal role in ...
- Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription
[作者：Fukuyama, R; Niculaita, R; Ng, KP; Obusez, E; Sanchez, J; Kalady, M; Aung, PP; Casey, G; Sizemore, N,期刊：Oncogene, 页码：6044-6055 , 文章类型： Article，,卷期：2008年27-46]
- Mutated in colorectal cancer (MCC) was originally identified as a candidate gene for familial adenomatous polyposis (FAP) but further study identified adenomatous polyposis coli (APC) as responsible for FAP and the physi...
- Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling
[作者：Dow, LE; Elsum, IA; King, CL; Kinross, KM; Richardson, HE; Humbert, PO,期刊：Oncogene, 页码：5988-6001 , 文章类型： Article，,卷期：2008年27-46]
- Activating mutations in genes of the Ras-mitogen-activated protein kinase (MAPK) pathway occur in approximately 30% of all human cancers; however, mutation of Ras alone is rarely sufficient to induce tumour development. ...
- Parkin as a tumor suppressor gene for hepatocellular carcinoma
[作者：Fujiwara, M; Marusawa, H; Wang, HQ; Iwai, A; Ikeuchi, K; Imai, Y; Kataoka, A; Nukina, N; Takahashi, R; Chiba, T,期刊：Oncogene, 页码：6002-6011 , 文章类型： Article，,卷期：2008年27-46]
- The parkin was first identified as a gene implicated in autosomal recessive juvenile Parkinsonism. Deregulation of the parkin gene, however, has been observed in various human cancers, suggesting that the parkin gene may...
- Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor
[作者：Hirose, K; Abramovich, C; Argiropoulos, B; Humphries, RK,期刊：Oncogene, 页码：6056-6067 , 文章类型： Article，,卷期：2008年27-46]
- PMX1 is a member of a non-clustered homeobox gene family, not normally expressed in hematopoietic cells, and first identified for its role in enhancing the binding of the serum response factor (SRF) to the serum responsi...
- Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon
[作者：Lukasiak, S; Schiller, C; Oehlschlaeger, P; Schmidtke, G; Krause, P; Legler, DF; Autschbach, F; Schirmacher, P; Breuhahn, K; Groettrup, M,期刊：Oncogene, 页码：6068-6074 , 文章类型： Article，,卷期：2008年27-46]
- The mRNA of the ubiquitin-like modifier FAT10 has been reported to be overexpressed in 90% of hepatocellular carcinoma (HCC) and in over 80% of colon, ovary and uterus carcinomas. Elevated FAT10 expression in malignancie...
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