- Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection
[作者:Aizaki, H; Morikawa, K; Fukasawa, M; Hara, H; Inoue, Y; Tani, H; Saito, K; Nishijima, M; Hanada, K; Matsuura, Y; Lai, MAC; Miyamura, T; Wakita, T; Suzuki, T,期刊:Journal of virology, 页码:5715-5724 , 文章类型: Article,,卷期:2008年82-12]
- In this study, we establish that cholesterol and sphingolipid associated with hepatitis C virus (HCV) particles are important for virion maturation and infectivity. In a recently developed culture system enabling study o...
- Subdominant CD8 T-cell epitopes account for protection against cytomegalovirus independent of immunodomination
[作者:Holtappels, R; Simon, CO; Munks, MW; Thomas, D; Deegen, P; Kuhnapfel, B; Daubner, T; Emde, SF; Podlech, J; Grzimek, NKA; Oehrlein-Karpi, SA; Hill, AB; Reddehase, MJ,期刊:Journal of virology, 页码:5781-5796 , 文章类型: Article,,卷期:2008年82-12]
- Cytomegalovirus (CW) infection continues to be a complication in recipients of hematopoietic stem cell transplantation (HSCT). Preexisting donor immunity is recognized as a favorable prognostic factor for the reconstitut...
- Partial functional complementation of a pseudorabies virus UL25 deletion mutant by herpes simplex virus type 1 pUL25 indicates overlapping functions of alphaherpesvirus pUL25 proteins
[作者:Kuhn, J; Leege, T; Klupp, BG; Granzow, H; Fuchs, W; Mettenleiter, TC,期刊:Journal of virology, 页码:5725-5734 , 文章类型: Article,,卷期:2008年82-12]
- Homologs of the UL25 gene product of herpes simplex virus 1 (HSV-1) are highly conserved among the Herpesviridae. However, their exact function during viral replication is unknown. Current evidence suggests that in the a...
- Vesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation
[作者:Oliere, S; Arguello, M; Mesplede, T; Tumilasci, V; Nakhaei, P; Stojdl, D; Sonenberg, N; Bell, J; Hiscott, J,期刊:Journal of virology, 页码:5735-5749 , 文章类型: Article,,卷期:2008年82-12]
- Vesicular stomatitis virus (VSV) is a candidate oncolytic virus that replicates and induces cell death in cancer cells while sparing normal cells. Although defects in the interferon antiviral response facilitate VSV onco...
- Scaffolding proteins altered in the ability to perform a conformational switch confer dominant lethal assembly defects
[作者:Cherwa, JE; Uchiyama, A; Fane, BA,期刊:Journal of virology, 页码:5774-5780 , 文章类型: Article,,卷期:2008年82-12]
- In the phi X174 procapsid crystal structure, 240 external scaffolding protein D subunits form 60 pairs of asymmetric dimers, D1D2 and D3D4, in a non-quasi-equivalent structure. To achieve this arrangement, alpha-helix 3 ...
- Insulin-like growth factor II mRNA binding protein 1 associates with gag protein of human immunodeficiency virus type 1, and its overexpression affects virus assembly
[作者:Zhou, YD; Rong, LW; Lu, JH; Pan, O; Liang, C,期刊:Journal of virology, 页码:5683-5692 , 文章类型: Article,,卷期:2008年82-12]
- The assembly of human immunodeficiency virus type 1 (HIV-1) particles is driven by viral Gag protein. This function of Gag not only benefits from its self-multimerization property but also depends on its interaction with...
- Replication in a superficial epithelial cell niche explains the lack of pathogenicity of primate foamy virus infections
[作者:Murray, SM; Picker, LJ; Axthelm, MK; Fludkins, K; Alpers, CE; Linial, ML,期刊:Journal of virology, 页码:5981-5985 , 文章类型: Article,,卷期:2008年82-12]
- Foamy viruses (FVs) are ancient retroviruses that are ubiquitous in nonhuman primates (NHPs). While FVs share many features with pathogenic retroviruses, such as human immunodeficiency virus, FV infections of their prima...
- The LEM domain proteins emerin and LAP2 alpha are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections
[作者:Mulky, A; Cohen, TV; Kozlov, SV; Korbei, B; Foisner, R; Stewart, CL; KewalRarnani, VN,期刊:Journal of virology, 页码:5860-5868 , 文章类型: Article,,卷期:2008年82-12]
- The human nuclear envelope proteins emerin and lamina-associated polypeptide 2 alpha (LAP2 alpha) have been proposed to aid in the early replication steps of human immunodeficiency virus type 1 (HIV-1) and murine leukemi...
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