- Tumor necrosis factor alpha protects against lethal West Nile Virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system
[作者:Shrestha, B; Zhang, B; Purtha, WE; Klein, RS; Diamond, MS,期刊:Journal of virology, 页码:8956-8964 , 文章类型: Article,,卷期:2008年82-18]
- West Nile virus (WNV) is a neurotropic flavivirus that has emerged globally as a significant cause of viral encephalitis in humans, especially in immunocompromised individuals. Previous studies have shown essential prote...
- Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates
[作者:Bartlett, EJ; Cruz, AM; Esker, J; Castano, A; Schomacker, H; Surman, SR; Hennessey, M; Boonyaratanakornkit, J; Pickles, RJ; Collins, PL; Murphy, BR; Schmidt, AC,期刊:Journal of virology, 页码:8965-8977 , 文章类型: Article,,卷期:2008年82-18]
- Recombinant human parainfluenza virus type 1 (rHPIV1) was modified to create rHPIV1-P(C-), a virus in which expression of the C proteins (C ', C, Y1, and Y2) was silenced without affecting the amino acid sequence of the ...
- Hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B
[作者:Diviney, S; Tuplin, A; Struthers, M; Armstrong, V; Elliott, RM; Simmonds, P; Evans, DJ,期刊:Journal of virology, 页码:9008-9022 , 文章类型: Article,,卷期:2008年82-18]
- The genome of hepatitis C virus (HCV) contains cis-acting replication elements (CREs) comprised of RNA stem-loop structures located in both the 5 ' and 3 ' noncoding regions (5 ' and 3 ' NCRs) and in the NS5B coding sequ...
- Matrix metalloproteinase 9 facilitates West Nile Virus entry into the brain
[作者:Wang, PH; Dai, JF; Bai, FW; Kong, KF; Wong, SJ; Montgomery, RR; Madri, JA; Fikrig, E,期刊:Journal of virology, 页码:8978-8985 , 文章类型: Article,,卷期:2008年82-18]
- West Nile virus (WNV) is the most-common cause of mosquito-borne encephalitis in the United States. Invasion of the brain by WNV is influenced by viral and host factors, and the molecular mechanism underlying disruption ...
- Enzootic nasal tumor virus envelope requires a very acidic pH for fusion activation and infection
[作者:Cote, M; Kucharski, TJ; Liu, SL,期刊:Journal of virology, 页码:9023-9034 , 文章类型: Article,,卷期:2008年82-18]
- Enzootic nasal tumor virus (ENTV) is a close relative of jaagsiekte sheep retrovirus (JSRV), and the two viruses use the same receptor, hyaluronidase 2 (Hyal2), for cell entry. We report here that, unlike the JSRV envelo...
- The broadly neutralizing anti-human immunodeficiency virus type 1 4E10 monoclonal antibody is better adapted to membrane-bound epitope recognition and blocking than 2F5
[作者:Huarte, N; Lorizate, M; Maeso, R; Kunert, R; Arranz, R; Valpuesta, JM; Nieva, JL,期刊:Journal of virology, 页码:8986-8996 , 文章类型: Article,,卷期:2008年82-18]
- The broadly neutralizing 2F5 and 4E10 monoclonal antibodies (MAbs) recognize epitopes within the membrane-proximal external region (MPER) that connects the human immunodeficiency virus type 1 (HIV-1) envelope gp41 ectodo...
- Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains
[作者:Adams, AP; Aronson, JF; Tardif, SD; Patterson, JL; Brasky, KM; Geiger, R; de la Garza, M; Carrion, R; Weaver, SC,期刊:Journal of virology, 页码:9035-9042 , 文章类型: Article,,卷期:2008年82-18]
- Eastern equine encephalitis virus ( EEEV) produces the most severe human arboviral disease in North America (NA) and is a potential biological weapon. However, genetically and antigenically distinct strains from South Am...
- Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates
[作者:Schwartz, RA; Lakdawala, SS; Eshleman, HD; Russell, MR; Carson, CT; Weitzman, MD,期刊:Journal of virology, 页码:9043-9055 , 文章类型: Article,,卷期:2008年82-18]
- The E1b55K and E4orf6 proteins of adenovirus type 5 (Ad5) assemble into a complex together with cellular proteins including cullin 5, elongins B and C, and Rbx1. This complex possesses E3 ubiquitin ligase activity and ta...
- An insect virus-encoded microRNA regulates viral replication
[作者:Hussain, M; Taft, RJ; Asgari, S,期刊:Journal of virology, 页码:9164-9170 , 文章类型: Article,,卷期:2008年82-18]
- MicroRNAs (miRNAs) are small (similar to 22 nucleotides) noncoding RNAs which play an essential role in gene regulation and affect a wide range of processes, including development, differentiation, and oncogenesis. Here ...
- Marked epitope- and allele- specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection
[作者:Brumme, ZL; Brumme, CJ; Carlson, J; Streeck, H; John, M; Eichbaum, Q; Block, BL; Baker, B; Kadie, C; Markowitz, M; Jessen, H; Kelleher, AD; Rosenberg, E; Kaldor, J; Yuki, Y; Carrington, M; Allen, TM; Mallal, S; Altfeld, M; Heckerman, D; Walker, BD,期刊:Journal of virology, 页码:9216-9227 , 文章类型: Article,,卷期:2008年82-18]
- During acute human immunodeficiency virus type 1 (HIV-1) infection, early host cellular immune responses drive viral evolution. The rates and extent of these mutations, however, remain incompletely characterized. In a co...
- Immune response in the absence of neurovirulence in mice infected with M protein mutant vesicular stomatitis virus
[作者:Ahmed, M; Marino, TR; Puckett, S; Kock, ND; Lyles, DS,期刊:Journal of virology, 页码:9273-9277 , 文章类型: Article,,卷期:2008年82-18]
- Matrix (M) protein mutants of vesicular stomatitis virus (VSV), such as rM51R-M virus, are less virulent than wild-type (wt) VSV strains due to their inability to suppress innate immunity. Studies presented here show tha...
- Functional homologies between avian and human alphaherpesvirus VP22 proteins in cell-to-cell spreading as revealed by a new cis-complementation assay
[作者:Blondeau, C; Marc, D; Courvoisier, K; Vautherot, JF; Denesvre, C,期刊:Journal of virology, 页码:9278-9282 , 文章类型: Article,,卷期:2008年82-18]
- VP22, encoded by the UL49 gene of Marek's disease virus (MDV), is indispensable for virus cell-to-cell spreading. We show herein that MDV UL49 can be functionally replaced with avian and human viral orthologs. Replacemen...
- Human cytomegalovirus infection alters the expression of cellular microRNA species that affect its replication
[作者:Wang, FZ; Weber, F; Croce, C; Liu, CG; Liao, XD; Pellett, PE,期刊:Journal of virology, 页码:9065-9074 , 文章类型: Article,,卷期:2008年82-18]
- The human genome encodes over 500 microRNAs (miRNAs), small RNAs (19 to 26 nucleotides [nt]) that regulate the expressions of diverse cellular genes. Many cellular processes are altered through a variety of mechanisms by...
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