- Use of fluorinated functionality in enzyme inhibitor development: Mechanistic and analytical advantages.
[作者:Berkowitz, David B.;Karukurichi, Kannan R.;de la Salud-Bea, Roberto;Nelson, David L.;McCune, Christopher D.;,期刊:Journal of Fluorine Chemistry, 页码:731-742 , 文章类型: 综述,,卷期:2008年129-9]
- A review. On the one hand, owing to its electronegativity, relatively small size, and notable leaving group ability from anionic intermediates, fluorine offers unique opportunities for mechanism-based enzyme inhibitor d...
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