- Curcumin induces high levels of topoisomerase I- and II DNA complexes in K562 leukemia cells
[作者:Lopez-Lazaro, M; Willmore, E; Jobson, A; Gilroy, KL; Curtis, H; Padget, K; Austin, CA,期刊:Journal of natural products, 页码:1884-1888 , 文章类型: Article,,卷期:2007年70-12]
- Recent data suggest that curcumin, a phytochemical with cancer chemopreventive potential, might be useful in the treatment of several solid and hematological malignancies. DNA topoisomerases (topos) are the target of sev...
- Spirolide toxin profile of Adriatic Alexandyium ostenfeldii cultures and structure elucidation of 27-hydroxy-13,19-didesmethyl spirolide C
[作者:Ciminiello, P; Dell'Aversano, C; Fattorusso, E; Forino, M; Grauso, L; Tartaglione, L; Guerrini, F; Pistocchi, R,期刊:Journal of natural products, 页码:1878-1883 , 文章类型: Article,,卷期:2007年70-12]
- This paper reports on the determination of the toxin profile of batch cultures of Alexandrium ostenfeldii established from water samples collected along the Emilia-Romagna coasts (Italy) in November 2003. Combined use of...
- Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis
[作者:Mencherini, T; Picerno, P; Scesa, C; Aqulno, R,期刊:Journal of natural products, 页码:1889-1894 , 文章类型: Article,,卷期:2007年70-12]
- Six new triterpenes (1-6) and four known compounds have been isolated from dried stems and leaves of Melissa officinalis. The known compounds were identified as quadranoside III, salvianic acid A, rosmarinic acid, and lu...
- Diterpenes, sesquiterpenes, and a C-15-acetogenin from the marine red alga Laurencia mariannensis
[作者:Ji, NY; Li, XM; Li, K; Ding, LP; Gloer, JB; Wang, BG,期刊:Journal of natural products, 页码:1901-1905 , 文章类型: Article,,卷期:2007年70-12]
- In addition to 10 known compounds (7-16), one new brominated diterpene, 10-hydroxykahukuene B (1), two new sesquiterpenes, 9-deoxyelatol (2) and isodactyloxene A (3), one new brominated C-15-acetogenin, laurenmariallene ...
- Crotonkinins A and B and related diterpenoids from Croton tonkinensis as anti-inflammatory and antitumor agents
[作者:Kuo, PC; Shen, YC; Yang, ML; Wang, SH; Thang, TD; Dung, NX; Chiang, PC; Lee, KH; Lee, EJ; Wu, TS,期刊:Journal of natural products, 页码:1906-1909 , 文章类型: Article,,卷期:2007年70-12]
- Cytotoxicity-guided phytochemical investigation of a methanolic extract of Croton tonkinensis afforded two new kaurane diterpenoids (1, 2) and 10 known ent-kaurane-type diterpenoids (3-12). The structures of I and 2 were...
- Brandisianins A-F, isoflavonoids isolated from Millettia brandisiana in a screening program for death-receptor expression enhancement activity
[作者:Kikuchi, H; Ohtsuki, T; Koyano, T; Kowithayakorn, T; Sakai, T; Ishibashi, M,期刊:Journal of natural products, 页码:1910-1914 , 文章类型: Article,,卷期:2007年70-12]
- In a screening study for natural products with tumor-selective apoptosis-inducing properties, six new isoflavonoids (1-6), named brandisianins A-F, respectively, have been isolated from a MeOH extract of the dried leaves...
- Sesquiterpene lactones from the roots of Ferula varia and their cytotoxic activity
[作者:Suzuki, K; Okasaka, M; Kashiwada, Y; Takaishi, Y; Honda, G; Ito, M; Takeda, Y; Kodzhimatov, OK; Ashurmetov, O; Sekiya, M; Ikeshiro, Y,期刊:Journal of natural products, 页码:1915-1918 , 文章类型: Article,,卷期:2007年70-12]
- The ethyl acetate-soluble fraction from a MeOH extract of the roots of Ferula varia gave six new sesquiterpene lactones (1-6) and five known sesquiterpenes (7-11). Their structures were established on the basis of spectr...
- Limitations in the deduction of carbon NMR spectra from the f(1) dimension of standard 2D heteronuclear experiments when applied to natural products
[作者:Sandusky, P,期刊:Journal of natural products, 页码:1895-1900 , 文章类型: Article,,卷期:2007年70-12]
- The structure elucidation of a natural product requires a set of NMR spectra that includes both carbon observe experiments, such as 1D carbon and DEPT, and proton observe experiments, such as HSQC, HMBC, and COSY. Becaus...
- Serinocyclins A and B, cyclic heptapeptides from Metarhizium anisopliae
[作者:Krasnoff, SB; Keresztes, I; Gillilan, RE; Szebenyi, DME; Donzelli, BGG; Churchill, ACL; Gibson, DM,期刊:Journal of natural products, 页码:1919-1924 , 文章类型: Article,,卷期:2007年70-12]
- Two new cyclic heptapeptides, serinocyclins A (1) and B (2), were isolated from conidia of the entomopathogenic fungus Metarhizium anisopliae. Structures were elucidated by a combination of mass spectrometric, NMR, and X...
- Cytochrome P3A4 inhibitors and other constituents of Fibraurea tinctoria
[作者:Su, CR; Ueng, YF; Dung, NX; Reddy, MVB; Wu, TS,期刊:Journal of natural products, 页码:1930-1933 , 文章类型: Article,,卷期:2007年70-12]
- Four ne v furanoditerpenoids, fibrauretin A (1), fibrauretinoside A (2), epi-fibrauretinoside A (3), and epi-12-palmatoside G (4), and a new ecdysteroid glucoside, fibraurecdyside A (5), together with seven known compoun...
- Alkaloids with human delta-opioid receptor binding affinity from the Australian rainforest tree Peripentadenia mearsii
[作者:Katavic, PL; Venables, DA; Guymer, GP; Forster, PI; Carroll, AR,期刊:Journal of natural products, 页码:1946-1950 , 文章类型: Article,,卷期:2007年70-12]
- Three new pyrrolidine alkaloids, peripentonine A-C (2-4), one known pyrrolidine alkaloid, peripentadenine (1), and one novel indolizidine alkaloid, mearsamine (5), were isolated from the leaves of Peripentadenia mearsii ...
- Chlorocyclinones A-D, chlorinated angucyclinones from Streptomyces sp strongly antagonizing rosiglitazone-induced PPAR-gamma activation
[作者:Potterat, O; Puder, C; Wagner, K; Bolek, W; Vettermann, R; Kauschke, SG,期刊:Journal of natural products, 页码:1934-1938 , 文章类型: Article,,卷期:2007年70-12]
- In the course of our screening to identify novel PPAR-gamma modulators for the potential treatment of type 2 diabetes, four new chlorinated angucyclinones, chlorocyclinones A-D (1-4), were isolated from the mycelium of S...
- Rhizochalins C and D from the sponge Rhizochalina incrustata. A rare threo-sphingolipid and a facile method for determination of the carbonyl position in alpha,omega-bifunctionalized ketosphingolipids
[作者:Makarieva, TN; Dmitrenok, PS; Zakharenko, AM; Denisenko, VA; Guzii, AG; Li, RH; Skepper, CK; Molinski, TF; Stonik, VA,期刊:Journal of natural products, 页码:1991-1998 , 文章类型: Article,,卷期:2007年70-12]
- Rhizochalins C and D (1, 2), new representatives of two-headed glycosphingolipids, were isolated from the sponge Rhizochalina incrustata. Rhizochalin D is an unexpected C-29 homologue of the canonical C-28 dimeric sphing...
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