- Tenacigenin B derivatives reverse P-glycoprotein-mediated multidrug resistance in HepG2/Dox cells
[作者:Hu, YJ; Shen, XL; Lu, HL; Zhang, YH; Huang, XA; Fu, LC; Fong, WF,期刊:Journal of natural products, 页码:1049-1051 , 文章类型: Article,,卷期:2008年71-6]
- Tenacissimoside A (1) and 11 alpha-O-benzoyl-12 beta-O-acetyltenacigenin B (2), two derivatives of tenacigenin B (3) from the plant Marsdenia tenacissima, reversed multidrug resistance in P-glycoprotein (Pgp)-overexpress...
- Inhibitors of bacterial multidrug efflux pumps from the resin glycosides of Ipomoea murucoides
[作者:Cherigo, L; Pereda-Miranda, R; Fragoso-Serrano, M; Jacobo-Herrera, N; Kaatz, GW; Gibbons, S,期刊:Journal of natural products, 页码:1037-1045 , 文章类型: Article,,卷期:2008年71-6]
- A reinvestigation of the CHCl3-soluble extract from flowers of the Mexican medicinal arborescent morning glory, Ipomoea murucoides, through preparative-scale recycling HPLC, yielded six new pentasaccharides, murucoidins ...
- Cytotoxic staurosporines from the marine ascidian Cystodytes solitus
[作者:Reyes, F; Fernandez, R; Rodriguez, A; Bueno, S; de Eguilior, C; Francesch, A; Cuevas, C,期刊:Journal of natural products, 页码:1046-1048 , 文章类型: Article,,卷期:2008年71-6]
- Two indolocarbazole alkaloids, 7-oxo-3,8,9-trihydroxystaurosporine (1) and 7-oxo-8,9-dihydroxy-4'-N-demethyl-staurosporine (2), were isolated from samples of the marine ascidian Cystodytes solitus. Their structures were ...
- ent-kaurane diterpenoids from Isodon japonicus
[作者:Hong, SS; Lee, SA; Han, XH; Hwang, JS; Lee, C; Lee, D; Hong, JT; Kim, Y; Lee, H; Hwang, BY,期刊:Journal of natural products, 页码:1055-1058 , 文章类型: Article,,卷期:2008年71-6]
- Five ent-kaurane diterpenoids, 6 beta,7 beta, 14 beta-trihydroxy-1 alpha,19-diacetoxy-7 alpha,20-epoxy-ent-kaur-16-en-15-one (1), 1 alpha,6 beta,7 beta-trihydroxy-11 alpha,19-diacetoxy-7 alpha,20-epoxy-ent-kaur-16-en-15-...
- Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis
[作者:Yu, ZG; Lang, G; Kajahn, I; Schmaljohann, R; Imhoff, JF,期刊:Journal of natural products, 页码:1052-1054 , 文章类型: Article,,卷期:2008年71-6]
- Two novel cyclodepsipeptides, scopularides A and B, were found in the fungus Scopulariopsis brevicaulis, which was isolated from the marine sponge Tethya aurantium. In addition, the known fungal metabolite paxilline was ...
- Aplysamine 6, an alkaloidal inhibitor of isoprenylcysteine carboxyl methyltransferase from the sponge Pseudoceratina sp.
[作者:Buchanan, MS; Carroll, AR; Fechner, GA; Boyle, A; Simpson, M; Addepalli, R; Avery, VM; Hooper, JNA; Cheung, T; Chen, HW; Quinn, RJ,期刊:Journal of natural products, 页码:1066-1067 , 文章类型: Article,,卷期:2008年71-6]
- The anticancer target isoprenylcysteine carboxyl methyltransferase (Icmt) was the focus of a natural product high-throughput screening campaign. The Australian marine sponge Pseudoceratina sp. yielded aplysamine 6, a new...
- Hualyzin, a symmetrical urea derivative isolated from Penicillium herquei isolate GA4
[作者:Ding, L; Fotso, S; Li, FC; Qin, S; Laatsch, H,期刊:Journal of natural products, 页码:1068-1069 , 文章类型: Article,,卷期:2008年71-6]
- Penicillium herquei isolate GA4 was isolated from the infected Conchocelis of Porphyra yezoensis. A large-scale fermentation using yeast extract sucrose medium and repeated chromatography afforded a new symmetrical urea ...
- Alkaloids from the Australian rainforest tree Ochrosia moorei
[作者:Carroll, AR; Addepalli, R; Fechner, G; Smith, J; Guymer, GP; Forster, PI; Quinn, RJ,期刊:Journal of natural products, 页码:1063-1065 , 文章类型: Article,,卷期:2008年71-6]
- High-throughput screening of a plant and marine invertebrate extract library to find natural products that down-regulate expression of pro-inflammatory genes associated with the glucocorticoid receptor ligand complex led...
- Cyclooxygenase (COX)-1 and -2 inhibitory labdane diterpenes from Crassocephalum mannii
[作者:Hegazy, MEF; Ohta, S; Abdel-latif, FF; Albadry, HA; Ohta, E; Pare, PW; Hirata, T,期刊:Journal of natural products, 页码:1070-1073 , 文章类型: Article,,卷期:2008年71-6]
- Two new labdane diterpenes, 8 alpha,19-dihydroxylabd-13E-en-15-oic acid (1) and 13,14,15,16-tetranorlabdane-8 alpha,12,14-triol (2), as well as an acetylated derivative, 8 alpha-0-beta-D-glucopyranosyllabd-13E-ene-15,19-...
- Selective inhibition of aromatase by a dihydroisocoumarin from Xytis pterygoblephara
[作者:Endringer, DC; Guimares, KG; Kondratyuk, TP; Pezzuto, JM; Braga, FC,期刊:Journal of natural products, 页码:1082-1084 , 文章类型: Article,,卷期:2008年71-6]
- Aromatase is a well-established target for the chemoprevention of breast cancer. The dihydroisocoumarin (3R,4R)-(-)-6-methoxy-1-oxo-3-pentyl-3,4-dihydro-1H-isochromen-4-yl acetate (1) (IC50 = 1.6 +/- 0.1 mu M), isolated ...
- Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus
[作者:Lang, G; Kalvelage, T; Peters, A; Wiese, J; Imhoff, JF,期刊:Journal of natural products, 页码:1074-1077 , 文章类型: Article,,卷期:2008年71-6]
- Three new peptides, xenortides A and B and xenematide, were isolated from a culture of the nematode-associated entomopathogenic bacterium Xenorhabdus nematophilus. Their structures were elucidated using NMR, MS, and chem...
- Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi
[作者:Zhang, W; Krohn, K; Draeger, S; Schulz, B,期刊:Journal of natural products, 页码:1078-1081 , 文章类型: Article,,卷期:2008年71-6]
- Three new isocoumarin derivatives (2-4) were isolated together with monocerin (1) from Microdochium bolleyi, an endophytic fungus from Fagonia cretica, a herbaceous plant of the semiarid coastal regions of Gomera. Compou...
- Claviceps nigricans and Claviceps grohii: Their alkaloids and phylogenetic placement
[作者:Pazoutova, S; Olsovska, J; Sulc, M; Chudickova, M; Flieger, M,期刊:Journal of natural products, 页码:1085-1088 , 文章类型: Article,,卷期:2008年71-6]
- Claviceps purpurea, C. grohii, C. zizaniae, C cyperi, and C. nigricans are closely related ergot fungi and form a monophyletic clade inside the genus Claviceps. Analysis of alkaloid content in C. nigricans selerotia usin...
- Aplysinoplides A-C, cytotoxic sesterterpenes from the marine sponge Aplysinopsis digitata
[作者:Ueoka, R; Nakao, Y; Fujii, S; van Soest, RWM; Matsunaga, S,期刊:Journal of natural products, 页码:1089-1091 , 文章类型: Article,,卷期:2008年71-6]
- Three sesterterpenoids, aplysinoplides A -C (1-3), were isolated from the marine sponge Aplysinopsis digitata. Their structures were determined on the basis of spectroscopic data. They exhibited cytotoxic activity agains...
- (Iso)-quinoline alkaloids from fungal fruiting bodies of Cortinarius subtortus
[作者:Teichert, A; Schmidt, J; Porzel, A; Arnold, N; Wessjohann, L,期刊:Journal of natural products, 页码:1092-1094 , 文章类型: Article,,卷期:2008年71-6]
- Chemical analysis of the fruiting bodies of the agaricoid fungus Cortinarius subtortus yielded three new natural products, two quinoline and one isocarbostyryl alkaloid. The structures of compounds 1-3 were determined by...
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