- Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update
[作者:Tumiattit, V; Bolognesi, ML; Minarini, A; Rosini, M; Milelli, A; Matera, R; Melchiorre, C,期刊:Expert Opinion on Therapeutic Patents, 页码:387-401 , 文章类型: Review,,卷期:2008年18-4]
Background: To date, the pharmacotherapy of Alzheimer's disease (AD) has been based on acetylcholinesterase inhibitors (AChEls), and more recently on an N-methyl-D-aspartate receptor antagonist. By increasing acetylch...
- Recent advances in the development of melanocortin-4 receptor ligands
[作者:Nozawa, D; Chaki, S; Nakazato, A,期刊:Expert Opinion on Therapeutic Patents, 页码:403-427 , 文章类型: Review,,卷期:2008年18-4]
Background: Melanocortins, which are derived from proopiomelanocortin, have been implicated in a variety of physiological processes. To date, five subtypes of melanocortin receptors have been identified, all of which ...
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