- Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3 center dot 4A protease inhibitors in treatment-naive subjects
[作者:Bartels, DJ; Zhou, Y; Zhang, EZ; Marcial, M; Byrn, RA; Pfeiffer, T; Tigges, AM; Adiwijaya, BS; Lin, C; Kwong, AD; Kieffer, TL,期刊:Journal of Infectious Diseases, 页码:800-807 , 文章类型: Article,,卷期:2008年198-6]
- Background. The prevalence and clinical implications of naturally occurring variants that are resistant to hepatitis C virus (HCV) protease inhibitors in treatment-naive patients has not been reported. We report here the...
- Chronic hepatitis C virus genotype 6 infection: Response to pegylated interferon and ribavirin
[作者:Fung, J; Lai, CL; Hung, I; Young, J; Cheng, C; Wong, D; Yuen, MF,期刊:Journal of Infectious Diseases, 页码:808-812 , 文章类型: Article,,卷期:2008年198-6]
- Background. To date, no study has evaluated pegylated interferon for the treatment of chronic infection with hepatitis C virus (HCV) genotype 6. We aimed to determine the efficacy of pegylated interferon plus ribavirin f...
- Patterns of cytomegalovirus reactivation are associated with distinct evolutive profiles of immune reconstitution after allogeneic hematopoietic stem cell transplantation
[作者:Moins-Teisserenc, H; Busson, M; Scieux, C; Bajzik, V; Cayuela, JM; Clave, E; de Latour, RP; Agbalika, F; Ribaud, P; Robin, M; Rocha, V; Gluckman, E; Charron, D; Socie, G; Toubert, A,期刊:Journal of Infectious Diseases, 页码:818-826 , 文章类型: Article,,卷期:2008年198-6]
- Tcell -mediated immunity is essential for the control of cytomegalovirus(CMV) infections in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Our aims were to identify patterns of CMV-sp...
- Age-specific prevalence, incidence, and duration of human papillomavirus infections in a cohort of 290 US men
[作者:Giuliano, AR; Lu, BB; Nielson, CM; Flores, R; Papenfuss, MR; Lee, JH; Abrahamsen, M; Harris, RB,期刊:Journal of Infectious Diseases, 页码:827-835 , 文章类型: Article,,卷期:2008年198-6]
- Background. Human papillomavirus (HPV) infections cause disease in men and women, and male-to-female HPV transmission influences the risk of cancer in females. The purpose of the present study was to describe the overall...
- Human metapneumovirus reinfection among children in Thailand determined by ELISA using purified soluble fusion protein
[作者:Pavlin, JA; Hickey, AC; Ulbrandt, N; Chan, YP; Endy, TP; Boukhvalova, MS; Chunsuttiwat, S; Nisalak, A; Libraty, DH; Green, S; Rothman, AL; Ennis, FA; Jarman, R; Gibbons, RV; Broder, CC,期刊:Journal of Infectious Diseases, 页码:836-842 , 文章类型: Article,,卷期:2008年198-6]
- Background. Human metapneumovirus (hMPV) is a newly discovered paramyxovirus that causes acute respiratory illness. Despite apparent near-universal exposure during early childhood, immunity is transient.Methods. An indir...
- CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients
[作者:Read, SW; Lempicki, RA; Di Mascio, M; Srinivasula, S; Burke, R; Sachau, W; Bosche, M; Adelsberger, JW; Sereti, I; Davey, RT; Tavel, JA; Huang, CY; Issaq, HJ; Fox, SD; Lane, HC; Kovacs, JA,期刊:Journal of Infectious Diseases, 页码:843-850 , 文章类型: Article,,卷期:2008年198-6]
- Administration of interleukin (IL)-2 to human immunodeficiency virus (HIV) -infected patients leads to significant increases in CD4 T cell counts. We previously have shown that IL-2 induces increased proliferation and su...
- Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants
[作者:Cote, HCF; Raboud, J; Bitnun, A; Alimenti, A; Money, DM; Maan, E; Costei, A; Gadawski, I; Diong, C; Read, S; Shen, S; Harrigan, PR; Burdge, DR; King, SM; Forbes, JC,期刊:Journal of Infectious Diseases, 页码:851-859 , 文章类型: Article,,卷期:2008年198-6]
- Background. The effects of perinatal antiretroviral therapy (ART) on infant mitochondrial function are not well known. We compared blood mitochondrial DNA (mtDNA) levels and mtDNA gene expression (mtRNA) in human immunod...
- The HCP5 single-nucleotide polymorphism: A simple screening tool for prediction of hypersensitivity reaction to abacavir
[作者:Colombo, S; Rauch, A; Rotger, M; Fellay, J; Martinez, R; Fux, C; Thurnheer, C; Gunthard, HF; Goldstein, DB; Furrer, H; Telenti, A,期刊:Journal of Infectious Diseases, 页码:864-867 , 文章类型: Article,,卷期:2008年198-6]
- The HLA-B* 5701 allele is predictive of hypersensitivity reaction to abacavir, a response herein termed " ABC-HSR." This study of 1103 individuals infected with human immunodeficiency virus assessed the usefulness of gen...
- Characteristics of HIV type 1 (HIV-1) glycoprotein 120 env sequences in mother-infant pairs infected with HIV-1 subtype CRF01_AE
[作者:Samleerat, T; Braibant, M; Jourdain, G; Moreau, A; Ngo-Giang-Huong, N; Leechanachai, P; Hemvuttiphan, J; Hinjiranandana, T; Changchit, T; Warachit, B; Suraseranivong, V; Lallemant, M; Barin, F,期刊:Journal of Infectious Diseases, 页码:868-876 , 文章类型: Article,,卷期:2008年198-6]
- We analyzed the characteristics of the envelope genes of human immunodeficiency virus type 1 in 17 mother-infant pairs infected with variants of the CRF01_ AE clade. A total of 353 sequences covering almost the entire gl...
- Mycobacterium tuberculosis sigma factor E regulon modulates the host inflammatory response
[作者:Fontan, PA; Aris, V; Alvarez, ME; Ghanny, S; Cheng, J; Soteropoulos, P; Trevani, A; Pine, R; Smith, I,期刊:Journal of Infectious Diseases, 页码:877-885 , 文章类型: Article,,卷期:2008年198-6]
- Mycobacterium tuberculosis survives in macrophages and usually subverts the bactericidal mechanisms of these phagocytes. The understanding of this hostpathogen interaction is relevant for the development of new treatment...
- Role of nitric oxide in defense of the central nervous system against Mycobacterium tuberculosis
[作者:Olin, MR; Armien, AG; Cheeran, MCJ; Rock, RB; Molitor, TW; Peterson, PK,期刊:Journal of Infectious Diseases, 页码:886-889 , 文章类型: Article,,卷期:2008年198-6]
- Murine models of tuberculous meningitis (TBM) have not reflected the severity of disease in humans. Based on reports that activated murine microglial cells, but not human microglial cells, express inducible nitric oxide ...
- Pilus backbone contributes to group B Streptococcus paracellular translocation through epithelial cells
[作者:Pezzicoli, A; Santi, I; Lauer, P; Rosini, R; Rinaudo, D; Grandi, G; Telford, JL; Soriani, M,期刊:Journal of Infectious Diseases, 页码:890-898 , 文章类型: Article,,卷期:2008年198-6]
- We have recently shown that group B Streptococcus ( GBS) crosses the epithelial barrier by a paracellular route. Here, we show that, although deletion of the pilus backbone protein did not affect GBS adhesiveness, it red...
- Increased expression of type-1 fimbriae by nonpathogenic Escherichia coli 83972 results in an increased capacity for catheter adherence and bacterial interference
[作者:Trautner, BW; Cevallos, ME; Li, HG; Riosa, S; Hull, RA; Hull, SI; Tweardy, DJ; Darouiche, RO,期刊:Journal of Infectious Diseases, 页码:899-906 , 文章类型: Article,,卷期:2008年198-6]
- Background. In vitro, urinary catheter colonization by avirulent Escherichia coli 83972 impedes subsequent catheter colonization by a variety of uropathogenic organisms. However, E. coli 83972 shows a low efficacy of adh...
- Effects of flagellin on the functions of follicle-associated epithelium
[作者:Chabot, SM; Shawi, M; Eaves-Pyles, T; Neutra, MR,期刊:Journal of Infectious Diseases, 页码:907-910 , 文章类型: Article,,卷期:2008年198-6]
- Bacterial flagellin activates innate immune responses by signaling through Toll- like receptor 5 and is a potential vaccine adjuvant. Mucosal lymphoid follicles, inductive sites for adaptive mucosal immune responses, are...
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