- RILP is required for the proper morphology and function of late endosomes
[作者:Progida, C; Malerod, L; Stuffers, S; Brech, A; Bucci, C; Stenmark, H,期刊:Journal of cell science, 页码:3729-3737 , 文章类型: Article,,卷期:2007年120-21]
- Lysosomal degradation of signalling receptors such as the epidermal growth factor (EGF) receptor (EGFR) is an important mechanism for termination of cell signalling. Such degradation involves the endosomal sorting of ubi...
- AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane
[作者:Grohmann, A; Tanneberger, K; Alzner, A; Schneikert, J; Behrens, J,期刊:Journal of cell science, 页码:3738-3747 , 文章类型: Article,,卷期:2007年120-21]
- APC is a multifunctional tumor suppressor protein that negatively controls Wnt signaling, but also regulates cell adhesion and migration by interacting with the plasma membrane and the microtubule cytoskeleton. Although ...
- RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells
[作者:Tedeschi, A; Ciciarello, M; Mangiacasale, R; Roscioli, E; Rensen, WM; Lavia, P,期刊:Journal of cell science, 页码:3748-3761 , 文章类型: Article,,卷期:2007年120-21]
- The GTPase RAN has an established role in spindle assembly and in mitotic progression, although not all mechanisms are fully understood in somatic cells. Here, we have downregulated RAN-binding protein 1 (RANBP1), a RAN ...
- Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins
[作者:Penuela, S; Bhalla, R; Gong, XQ; Cowan, KN; Celetti, SJ; Cowan, BJ; Bai, D; Shao, Q; Laird, DW,期刊:Journal of cell science, 页码:3772-3783 , 文章类型: Article,,卷期:2007年120-21]
- Pannexins are mammalian orthologs of the invertebrate gap junction proteins innexins and thus have been proposed to play a role in gap junctional intercellular communication. Localization of exogenously expressed pannexi...
- RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle
[作者:Fritz, N; Morel, JL; Jeyakumar, LH; Fleischer, S; Allen, PD; Mironneau, J; Macrez, N,期刊:Journal of cell science, 页码:3784-3791 , 文章类型: Article,,卷期:2007年120-21]
- Ryanodine receptor subtype 1 (RyR1) has been primarily characterized in skeletal muscle but several studies have revealed its expression in smooth muscle. Here, we used Ryr1-null mice to investigate the role of this isof...
- Supervillin slows cell spreading by facilitating myosin II activation at the cell periphery
[作者:Takizawa, N; Ikebe, R; Ikebe, M; Luna, EJ,期刊:Journal of cell science, 页码:3792-3803 , 文章类型: Article,,卷期:2007年120-21]
- During cell migration, myosin II modulates adhesion, cell protrusion and actin organization at the leading edge. We show that an F-actin- and membrane-associated scaffolding protein, called supervillin (SV, p205), binds ...
- Distinct endocytic pathways identified in tobacco pollen tubes using charged nanogold
[作者:Moscatelli, A; Ciampolini, F; Rodighiero, S; Onelli, E; Cresti, M; Santo, N; Idilli, A,期刊:Journal of cell science, 页码:3804-3819 , 文章类型: Article,,卷期:2007年120-21]
- In an attempt to dissect endocytosis in Nicotiana tabacum L. pollen tubes, two different probes - positively or negatively charged nanogold - were employed. The destiny of internalized plasma membrane domains, carrying n...
- SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility
[作者:Tournaviti, S; Hannemann, S; Terjung, S; Kitzing, TM; Stegmayer, C; Ritzerfeld, J; Walther, P; Grosse, R; Nickel, W; Fackler, OT,期刊:Journal of cell science, 页码:3820-3829 , 文章类型: Article,,卷期:2007年120-21]
- SH4 domains provide bipartite membrane-targeting signals for oncogenic Src family kinases. Here we report the induction of non-apoptotic plasma membrane (PM) blebbing as a novel and conserved activity of SH4 domains deri...
- Activin increases the number of synaptic contacts and the length of dendritic spine necks by modulating spinal actin dynamics
[作者:Shoji-Kasai, Y; Ageta, H; Hasegawa, Y; Tsuchida, K; Sugino, H; Inokuchi, K,期刊:Journal of cell science, 页码:3830-3837 , 文章类型: Article,,卷期:2007年120-21]
- Long-lasting modifications in synaptic transmission depend on de novo gene expression in neurons. The expression of activin, a member of the transforming growth factor beta (TGF-beta) superfamily, is upregulated during h...
- Regulation of P2X(4) receptors by lysosomal targeting, glycan protection and exocytosis
[作者:Qureshi, OS; Paramasivam, A; Yu, JCH; Murrell-Lagnado, RD,期刊:Journal of cell science, 页码:3838-3849 , 文章类型: Article,,卷期:2007年120-21]
- The P2X(4) receptor has a widespread distribution in the central nervous system and the periphery, and plays an important role in the function of immune cells and the vascular system. Its upregulation in microglia contri...
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