- Plasmodium falciparum possesses two GRASP proteins that are differentially targeted to the Golgi complex via a higher- and lower-eukaryote-like mechanism
[作者:Struck, NS; Herrmann, S; Langer, C; Krueger, A; Foth, BJ; Engelberg, K; Cabrera, AL; Haase, S; Treeck, M; Marti, M; Cowman, AF; Spielmann, T; Gilberger, TW,期刊:Journal of cell science, 页码:2123-2129 , 文章类型: Article,,卷期:2008年121-13]
- Plasmodium falciparum, the causative agent of malaria, relies on a complex protein-secretion system for protein targeting into numerous subcellular destinations. Recently, a homologue of the Golgi re-assembly stacking pr...
- Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2
[作者:Murphy, JE; Vohra, RS; Dunn, S; Holloway, ZG; Monaco, AP; Homer-Vanniasinkam, S; Walker, JH; Ponnambalam, S,期刊:Journal of cell science, 页码:2136-2147 , 文章类型: Article,,卷期:2008年121-13]
- The LOX-1 scavenger receptor recognises pro-atherogenic oxidised low-density lipoprotein (OxLDL) particles and is implicated in atherosclerotic plaque formation, but this mechanism is not well understood. Here we show ev...
- DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena
[作者:Mochizuki, K; Novatchkova, M; Loidl, J,期刊:Journal of cell science, 页码:2148-2158 , 文章类型: Article,,卷期:2008年121-13]
- During meiosis, the micronuclei of the ciliated protist Tetrahymena thermophila elongate dramatically. Within these elongated nuclei, chromosomes are arranged in a bouquet-like fashion and homologous pairing and recombin...
- Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network
[作者:Han, JB; Wang, YG; Wang, SM; Chi, CW,期刊:Journal of cell science, 页码:2217-2223 , 文章类型: Article,,卷期:2008年121-13]
- Furin is a proprotein convertase that cycles between the plasma membrane, endosomes and the trans-Golgi network (TGN), maintaining a predominant distribution in the latter. Mint3, a member of the Mint protein family, is ...
- E-cadherin controls beta-catenin and NF-kappa B transcriptional activity in mesenchymal gene expression
[作者:Solanas, G; Porta-de-la-Riva, M; Agusti, C; Casagolda, D; Sanchez-Aguilera, F; Larriba, MJ; Pons, F; Peiro, S; Escriva, M; Munoz, A; Dunach, M; de Herreros, AG; Baulida, J,期刊:Journal of cell science, 页码:2224-2234 , 文章类型: Article,,卷期:2008年121-13]
- E-cadherin and its transcriptional repressor Snail1 ( Snai1) are two factors that control epithelial phenotype. Expression of Snail1 promotes the conversion of epithelial cells to mesenchymal cells, and occurs concomitan...
- Nucleolar localization of TERT is unrelated to telomerase function in human cells
[作者:Lin, J; Jin, R; Zhang, B; Chen, H; Bai, YX; Yang, PX; Han, SW; Xie, YH; Huang, PT; Huang, CF; Huang, JJ,期刊:Journal of cell science, 页码:2169-2176 , 文章类型: Article,,卷期:2008年121-13]
- Telomerase maintains telomere length and has been implicated in both aging and carcinogenesis of human cells. This enzyme is a specialized ribonucleoprotein (RNP) complex, minimally consisting of two essential components...
- PPAR gamma accelerates cellular senescence by inducing p16(INK4 alpha) expression in human diploid fibroblasts
[作者:Gan, Q; Huang, J; Zhou, R; Niu, J; Zhu, XJ; Wang, J; Zhang, ZY; Tong, TJ,期刊:Journal of cell science, 页码:2235-2245 , 文章类型: Article,,卷期:2008年121-13]
- Peroxisome proliferator-activated receptor gamma ( PPAR gamma) plays an important role in the inhibition of cell growth by promoting cell-cycle arrest, and PPAR gamma activation induces the expression of p16(INK4 alpha) ...
- TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy
[作者:Gervasio, OL; Whitehead, NP; Yeung, EW; Phillips, WD; Allen, DG,期刊:Journal of cell science, 页码:2246-2255 , 文章类型: Article,,卷期:2008年121-13]
- Transient receptor potential canonical 1 (TRPC1), a widely expressed calcium (Ca2+)-permeable channel, is potentially involved in the pathogenesis of Duchenne muscular dystrophy (DMD). Ca2+ influx through stretch-activat...
- Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation
[作者:Johnson, KA; Rose, DM; Terkeltaub, RA,期刊:Journal of cell science, 页码:2256-2264 , 文章类型: Article,,卷期:2008年121-13]
- Two transglutaminases (TGs), factor XIIIA (FXIIIA) and TG2, undergo physiologic upregulation in growth plate hypertrophic chondrocytes, and pathological upregulation in osteoarthritic cartilage. Externalization of guanin...
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