- Novel functions of the CD34 family
[作者:Nielsen, JS; McNagny, KM,期刊:Journal of cell science, 页码:3683-3692 , 文章类型: Article,,卷期:2008年121-22]
- For almost 30 years, the cell-surface protein CD34 has been widely used as a marker to assist in the identification and isolation of hematopoietic stem cells (HSCs) and progenitors in preparation for bone-marrow transpla...
- Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes
[作者:Pfaff, D; Heroult, M; Riedel, M; Reiss, Y; Kirmse, R; Ludwig, T; Korff, T; Hecker, M; Augustin, HG,期刊:Journal of cell science, 页码:3842-3850 , 文章类型: Article,,卷期:2008年121-22]
- The vascular endothelium is a crucial interface that controls the recruitment of circulating leukocytes. Based on the luminal expression of the ephrin-B2 ligand by endothelial cells (ECs) and the expression of EphB recep...
- Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei
[作者:Absalon, S; Blisnick, T; Bonhivers, M; Kohl, L; Cayet, N; Toutirais, G; Buisson, J; Robinson, D; Bastin, P,期刊:Journal of cell science, 页码:3704-3716 , 文章类型: Article,,卷期:2008年121-22]
- In trypanosomes, the flagellum is rooted in the flagellar pocket, a surface micro-domain that is the sole site for endocytosis and exocytosis. By analysis of anterograde or retrograde intraflagellar transport in IFT88(RN...
- Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons
[作者:Diaz-Hernandez, M; del Puerto, A; Diaz-Hernandez, JI; Diez-Zaera, M; Lucas, JJ; Garrido, JJ; Miras-Portugal, MT,期刊:Journal of cell science, 页码:3717-3728 , 文章类型: Article,,卷期:2008年121-22]
- During the establishment of neural circuits, the axons of neurons grow towards their target regions in response to both positive and negative stimuli. Because recent reports show that Ca2+ transients in growth cones nega...
- PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics
[作者:Smith, SD; Jaffer, ZM; Chernoff, J; Ridley, AJ,期刊:Journal of cell science, 页码:3729-3736 , 文章类型: Article,,卷期:2008年121-22]
- PAK1 is a member of the p21-activated kinase (PAK) family of serine/threonine kinases that are activated by the Rho GTPases Rac and Cdc42, and are implicated in regulating morphological polarity, cell migration and adhes...
- A dominant vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and causes posterior cataracts in transgenic mice
[作者:Bornheim, R; Muller, M; Reuter, U; Herrmann, H; Bussow, H; Magin, TM,期刊:Journal of cell science, 页码:3737-3746 , 文章类型: Article,,卷期:2008年121-22]
- Vimentin is the main intermediate filament ( IF) protein of mesenchymal cells and tissues. Unlike other IF-/- mice, vimentin(-/-) mice provided no evidence of an involvement of vimentin in the development of a specific d...
- Signaling through urokinase and urokinase receptor in lung cancer cells requires interactions with beta 1 integrins
[作者:Tang, CH; Hill, ML; Brumwell, AN; Chapman, HA; Wei, Y,期刊:Journal of cell science, 页码:3747-3756 , 文章类型: Article,,卷期:2008年121-22]
- The urokinase receptor (uPAR) is upregulated upon tumor cell invasion and correlates with poor lung cancer survival. Although a cis-interaction with integrins has been ascribed to uPAR, whether this interaction alone is ...
- Identification of a developmentally regulated pathway of membrane retrieval in neuronal growth cones
[作者:Bonanomi, D; Fornasiero, EF; Valdez, G; Halegoua, S; Benfenati, F; Menegon, A; Valtorta, F,期刊:Journal of cell science, 页码:3757-3769 , 文章类型: Article,,卷期:2008年121-22]
- The growth-cone plasma membrane constantly reconfigures during axon navigation and upon target recognition. The identity and regulation of the membrane pathway(s) participating in remodeling of the growth-cone surface re...
- Structural determinants of the cellular localization and shuttling of TDP-43
[作者:Ayala, YM; Zago, P; D'Ambrogio, A; Xu, YF; Petrucelli, L; Buratti, E; Baralle, FE,期刊:Journal of cell science, 页码:3778-3785 , 文章类型: Article,,卷期:2008年121-22]
- TDP-43 (also known as TARDBP) regulates different processes of gene expression, including transcription and splicing, through RNA and DNA binding. Moreover, recent reports have shown that the protein interacts with the 3...
- A non-apoptotic role for caspase-9 in muscle differentiation
[作者:Murray, TVA; McMahon, JM; Howley, BA; Stanley, A; Ritter, T; Mohr, A; Zwacka, R; Fearnhead, HO,期刊:Journal of cell science, 页码:3786-3793 , 文章类型: Article,,卷期:2008年121-22]
- Caspases, a family of cysteine proteases most often investigated for their roles in apoptosis, have also been demonstrated to have functions that are vital for the efficient execution of cell differentiation. One such ro...
- Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
[作者:Engler, AJ; Carag-Krieger, C; Johnson, CP; Raab, M; Tang, HY; Speicher, DW; Sanger, JW; Sanger, JM; Discher, DE,期刊:Journal of cell science, 页码:3794-3802 , 文章类型: Article,,卷期:2008年121-22]
- Fibrotic rigidification following a myocardial infarct is known to impair cardiac output, and it is also known that cardiomyocytes on rigid culture substrates show a progressive loss of rhythmic beating. Here, isolated e...
- Dissecting the involvement of formins in Bud6p-mediated cortical capture of microtubules in S. cerevisiae
[作者:Delgehyr, N; Lopes, CSJ; Moir, CA; Huisman, SM; Segal, M,期刊:Journal of cell science, 页码:3803-3814 , 文章类型: Article,,卷期:2008年121-22]
- In S. cerevisiae, spindle orientation is linked to the inheritance of the 'old' spindle pole by the bud. A player in this asymmetric commitment, Bud6p, promotes cortical capture of astral microtubules. Additionally, Bud6...
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