- ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage
[作者:Medhurst, AL; Warmerdam, DO; Akerman, I; Verwayen, EH; Kanaar, R; Smits, VAJ; Lakin, ND,期刊:Journal of cell science, 页码:3933-3940 , 文章类型: Article,,卷期:2008年121-23]
- The cell cycle checkpoint kinase Chk1 is phosphorylated and activated by ATR in response to DNA damage and is crucial for initiating the DNA damage response. A number of factors act in concert with ATR to facilitate Chk1...
- Myc increases self-renewal in neural progenitor cells through Miz-1
[作者:Kerosuo, L; Piltti, K; Fox, H; Angers-Loustau, A; Hayry, V; Eilers, M; Sarioia, H; Wartiovaara, K,期刊:Journal of cell science, 页码:3941-3950 , 文章类型: Article,,卷期:2008年121-23]
- The mechanisms underlying the decision of a stem or progenitor cell to either self-renew or differentiate are incompletely understood. To address the role of Myc in this process, we expressed different forms of the proto...
- BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity
[作者:Gamell, C; Osses, N; Bartrons, R; Rueckle, T; Camps, M; Rosa, JL; Ventura, F,期刊:Journal of cell science, 页码:3960-3970 , 文章类型: Article,,卷期:2008年121-23]
- Bone morphogenetic proteins (BMPs) are potent regulators of several cellular events. We report that exposure of C2C12 cells to BMP2 leads to an increase in cell migration and a rapid rearrangement of the actin filaments ...
- The consequences of tetraploidy and aneuploidy
[作者:Storchova, Z; Kuffer, C,期刊:Journal of cell science, 页码:3859-3866 , 文章类型: Article,,卷期:2008年121-23]
- Polyploidy, an increased number of chromosome sets, is a surprisingly common phenomenon in nature, particularly in plants and fungi. In humans, polyploidy often occurs in specific tissues as part of terminal differentiat...
- Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C-elegans
[作者:Yamashiro, S; Cox, EA; Baillie, DL; Hardin, JD; Ono, S,期刊:Journal of cell science, 页码:3867-3877 , 文章类型: Article,,卷期:2008年121-23]
- Sarcomeric organization of thin and thick filaments in striated muscle is important for the efficient generation of contractile forces. Sarcomeric actin filaments are uniform in their lengths and regularly arranged in a ...
- Growth-speed-correlated localization of exocyst and polarisome components in growth zones of Ashbya gossypii hyphal tips
[作者:Koehli, M; Galati, V; Boudier, K; Roberson, RW; Philippsen, P,期刊:Journal of cell science, 页码:3878-3889 , 文章类型: Article,,卷期:2008年121-23]
- We use the fungus Ashbya gossypii to investigate how its polar growth machinery is organized to achieve sustained hyphal growth. In slowly elongating hyphae exocyst, cell polarity and polarisome proteins permanently loca...
- Effect of cell shape and packing density on granulosa cell proliferation and formation of multiple layers during early follicle development in the ovary
[作者:Da Silva-Buttkus, P; Jayasooriya, GS; Mora, JM; Mobberley, M; Ryder, TA; Baithun, M; Stark, J; Franks, S; Hardy, K,期刊:Journal of cell science, 页码:3890-3900 , 文章类型: Article,,卷期:2008年121-23]
- The postnatal mouse ovary is rich in quiescent and early-growing oocytes, each one surrounded by a layer of somatic granulosa cells (GCs) on a basal lamina. As oocytes start to grow the GCs change shape from flattened to...
- Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions
[作者:Court, FA; Gillingwater, TH; Melrose, S; Sherman, DL; Greenshields, KN; Morton, AJ; Harris, JB; Willison, HJ; Ribchester, RR,期刊:Journal of cell science, 页码:3901-3911 , 文章类型: Article,,卷期:2008年121-23]
- Neuromuscular junctions (NMJs) are normally thought to comprise three major cell types: skeletal muscle fibres, motor neuron terminals and perisynaptic terminal Schwann cells. Here we studied a fourth population of junct...
- The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation
[作者:Rapley, J; Nicolas, M; Groen, A; Regue, L; Bertran, MT; Caelles, C; Avruch, J; Roig, J,期刊:Journal of cell science, 页码:3912-3921 , 文章类型: Article,,卷期:2008年121-23]
- Nek6 and Nercc1 (also known as Nek9) belong to the NIMA family of protein kinases. Nercc1 is activated in mitosis, whereupon it binds, phosphorylates and activates Nek6. Interference with Nek6 or Nercc1 in mammalian cell...
- The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes
[作者:Bakshi, R; Zaidi, SK; Pande, S; Hassan, MQ; Young, DW; Montecino, M; Lian, JB; van Wijnen, AJ; Stein, JL; Stein, GS,期刊:Journal of cell science, 页码:3981-3990 , 文章类型: Article,,卷期:2008年121-23]
- RUNX1/AML1 is required for definitive hematopoiesis and is frequently targeted by chromosomal translocations in acute myeloid leukemia (AML). The t(8;21)-related AML1-ETO fusion protein blocks differentiation of myeloid ...
- Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC (vol 121, pg 2850, 2008)
[作者:Hoogstraten, D; Bergink, S; Ng, JMY; Verbiest, VHM; Luijsterburg, MS; Geverts, B; Raams, A; Dinant, C; Hoeijmakers, JHJ; Vermeulen, W; Houtsmuller, AB,期刊:Journal of cell science, 页码:3991-3991 , 文章类型: Correction,,卷期:2008年121-23]
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