- Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster
[作者：Taguchi, A; Yanagisawa, K; Tanaka, M; Cao, K; Matsuyama, Y; Goto, H; Takahashi, T,期刊：Cancer research, 页码：5540-5545 , 文章类型： Article，,卷期：2008年68-14]
- MicroRNAs (miRNAs) are a distinct class of small noncoding RNAs that posttranscriptionally repress expression of target genes through imperfect base pairing with the 3' untranslated region. We previously reported amplifi...
- Rethinking brain tumors: The fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop
[作者：Reilly, KM; Rubin, JB; Gilbertson, RJ; Garbow, JR; Roussel, MF; Gutmann, DH,期刊：Cancer research, 页码：5508-5511 , 文章类型： Article，,卷期：2008年68-14]
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- XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: From molecular pathogenesis to targeted therapy in leukemia and solid tumors
[作者：Hackanson, B; Becker, H; Berg, T; Binder, M; Dierks, C; Duque-Afonso, J; Lairmore, MD; Schafer, HS; Schnitzler, M; Zeiser, R; Martens, U; Mertelsmann, R; Lubbert, M,期刊：Cancer research, 页码：5512-5518 , 文章类型： Article，,卷期：2008年68-14]
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- A novel therapeutic combination using PD 0332991 and bortezomib: Study in the 5T33MM myeloma model
[作者：Menu, E; Garcia, J; Huang, X; Di Liberto, M; Toogood, PL; Chen, I; Vanderkerken, K; Chen-Kiang, S,期刊：Cancer research, 页码：5519-5523 , 文章类型： Article，,卷期：2008年68-14]
- Multiple myeloma (MM) remains incurable partly because no effective cell cycle-based therapy has been available to both control tumor cell proliferation and synergize with cytotoxic killing. PD 0332991 is an orally activ...
- Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma
[作者：Marks, JL; Gong, YX; Chitale, D; Golas, B; McLellan, MD; Kasai, Y; Ding, L; Mardis, ER; Wilson, RK; Solit, D; Levine, R; Michel, K; Thomas, RK; Rusch, VW; Ladanyi, M; Pao, W,期刊：Cancer research, 页码：5524-5528 , 文章类型： Article，,卷期：2008年68-14]
- Genetic lesions affecting a number of kinases and other elements within the epidermal growth factor receptor (EGFR) signaling pathway have been implicated in the pathogenesis of human non-small-cell lung cancer (NSCLC). ...
- Monitoring serial changes in circulating human breast cancer cells in murine xenograft models
[作者：Eliane, JP; Repollet, M; Luker, KE; Brown, M; Rae, JM; Dontu, G; Schott, AF; Wicha, M; Doyle, GV; Hayes, DF; Luker, GD,期刊：Cancer research, 页码：5529-5532 , 文章类型： Article，,卷期：2008年68-14]
- Circulating tumor cells (CTC) are emerging as a powerful prognostic and predictive biomarker in several types of cancer, including breast, colon, and prostate. Studies of CTC in metastasis and further development of CTC ...
- Tissue-specific promoters active in CD44(+)CD24(-/low) breast cancer cells
[作者：Bauerschmitz, GJ; Ranki, T; Kangasniemi, L; Ribacka, C; Eriksson, M; Porten, M; Herrmann, I; Ristimaki, A; Virkkunen, P; Tarkkanen, M; Hakkarainen, T; Kanerva, A; Rein, D; Pesonen, S; Hemminki, A,期刊：Cancer research, 页码：5533-5539 , 文章类型： Article，,卷期：2008年68-14]
- It has been proposed that human tumors contain stem cells that have a central role in tumor initiation and posttreatment relapse. Putative breast cancer stem cells may reside in the CD44(+)CD24(-/low) population. Oncolyt...
- Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells
[作者：Nandi, S; Ulasov, IV; Tyler, MA; Sugihara, AQ; Molinero, L; Han, Y; Zhu, ZB; Lesniak, MS,期刊：Cancer research, 页码：5778-5784 , 文章类型： Article，,卷期：2008年68-14]
- To improve the efficacy and selectivity of virotherapy for malignant glioma, we designed a strategy to amplify adenoviral replication in conjunction with radiotherapy using a radioinducible promoter. First, we compared t...
- Special linker between macrophage and hematopoietic malignant cells: Membrane form of macrophage colony-stimulating factor
[作者：Wang, L; Zheng, GG; Ma, CH; Lin, YM; Zhang, HY; Ma, YY; Chong, JH; Wu, KF,期刊：Cancer research, 页码：5639-5647 , 文章类型： Article，,卷期：2008年68-14]
- The membrane form of macrophage colony-stimulating factor (mM-CSF) is an alternative splicing variant of this cytokine. Although its high expression was detected in hematopoietic malignancies, its physiologic and patholo...
- SerpinB2 protection of retinoblastoma protein from calpain enhances tumor cell survival
[作者：Tonnetti, L; Netzel-Arnett, S; Darnell, GA; Hayes, T; Buzza, MS; Anglin, IE; Suhrbier, A; Antalis, TM,期刊：Cancer research, 页码：5648-5657 , 文章类型： Article，,卷期：2008年68-14]
- The tumor suppressor retinoblastoma protein (Rb) plays a pivotal role in the regulation of cell proliferation and sensitivity to apoptosis through binding to E2F transcription factors. Loss of Rb in response to genotoxic...
- CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region
[作者：Nguyen, P; Cui, HM; Bisht, KS; Sun, LC; Patel, K; Lee, RS; Kugoh, H; Oshimura, M; Feinberg, AP; Gius, D,期刊：Cancer research, 页码：5546-5551 , 文章类型： Article，,卷期：2008年68-14]
- The CTCF paralog BORIS (brother of the regulator of imprinted sites) is an insulator DNA-binding protein thought to play a role in chromatin organization and gene expression. Under normal physiologic conditions, BORIS is...
- Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development
[作者：Hu, Z; Liu, Y; Zhang, CB; Zhao, Y; He, W; Han, L; Yang, LL; Hopkins, KM; Yang, X; Lieberman, HB; Hang, HY,期刊：Cancer research, 页码：5552-5561 , 文章类型： Article，,卷期：2008年68-14]
- The Rad9 gene is evolutionarily conserved from yeast to humans and plays crucial roles in genomic maintenance, DNA repair, and cell cycle checkpoint controls. However, the function of this gene with respect to tumorigene...
- The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects
[作者：Moserle, L; Indraccolo, S; Ghisi, M; Frasson, C; Fortunato, E; Canevari, S; Miotti, S; Tosello, V; Zamarchi, R; Corradin, A; Minuzzo, S; Rossi, E; Basso, G; Amadori, A,期刊：Cancer research, 页码：5658-5668 , 文章类型： Article，,卷期：2008年68-14]
- The side population (SP), recently identified in several normal tissues and in a variety of tumors based on its ability to extrude some fluorescent dyes, may comprise cells endowed with stem cell features. In this study,...
- GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
[作者：Ronneberg, JA; Tost, J; Solvang, HK; Alnaes, GIG; Johansen, FE; Brendeford, EM; Yakhini, Z; Gut, IG; Lonning, PE; Borresen-Dale, AL; Gabrielsen, OS; Kristensen, VN,期刊：Cancer research, 页码：5562-5571 , 文章类型： Article，,卷期：2008年68-14]
- The CpG island spanning the transcription start of the glutathione S-transferase P1 becomes methylated in a variety of human cancers including breast cancer. To study the effect of sequence variation on hypermethylation ...
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