- EBV latent membrane protein 1 effects on plakoglobin, cell growth, and migration
[作者：Shair, KHY; Schnegg, CI; Raab-Traub, N,期刊：Cancer research, 页码：6997-7005 , 文章类型： Article，,卷期：2008年68-17]
- Latent membrane protein 1 (LMP1), the major oncoprotein of EBV, is likely responsible for many of the altered cellular growth properties in EBV-associated cancers, including nasopharyngeal carcinoma (NPC). In this study,...
- The relative contribution of point mutations and genomic rearrangements in BRCA1 and BRCA2 in high-risk breast cancer families
[作者：Palma, MD; Domchek, SM; Stopfer, J; Erlichman, J; Siegfried, JD; Tigges-Cardwell, J; Mason, BA; Rebbeck, TR; Nathanson, KL,期刊：Cancer research, 页码：7006-7014 , 文章类型： Article，,卷期：2008年68-17]
- The demand for BRCA1 and BRCA2 mutation screening is increasing as their identification will affect medical management. However, both the contribution of different mutation types in BRCA1 and BRCA2 and whom should be off...
- Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor
[作者：Witters, L; Scherle, P; Friedman, S; Fridman, J; Caulder, E; Newton, R; Lipton, A,期刊：Cancer research, 页码：7083-7089 , 文章类型： Article，,卷期：2008年68-17]
- The ErbB family of receptors is overexpressed in numerous human tumors. Overexpression correlates with poor prognosts and resistance to therapy. Use of ErbB-specific antibodies to the receptors (Herceptin or Erbitux) or ...
- Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer
[作者：Sun, T; Zhou, YF; Yang, M; Hu, ZB; Tan, W; Han, XH; Shi, YK; Yao, JR; Guo, YL; Yu, DK; Tian, T; Zhou, XY; Shen, HB; Lin, DX,期刊：Cancer research, 页码：7025-7034 , 文章类型： Article，,卷期：2008年68-17]
- Antitumor T lymphocytes play a pivotal role in immunosurveillance of malignancy. The CTL antigen 4 (CTLA-4) is a vital negative regulator of T-cell activation and proliferation. This study examined whether genetic polymo...
- Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil
[作者：Zhao, HY; Ooyama, A; Yamamoto, M; Ikeda, RJ; Haraguchi, M; Tabata, S; Furukawa, T; Che, XF; Zhang, SX; Oka, T; Fukushima, M; Nakagawa, M; Ono, M; Kuwano, M; Akiyama, SI,期刊：Cancer research, 页码：7035-7041 , 文章类型： Article，,卷期：2008年68-17]
- 5-Fluorouracil (5-FU) is one of the most commonly used anticancer drugs in chemotherapy against various solid tumors. 5-FU dose-dependently increased the expression levels of intrinsic antiangiogenic factor thrombospondi...
- Vessel fractions in tumor xenografts depicted by flow- or contrast-sensitive three-dimensional high-frequency Doppler ultrasound respond differently to antiangiogenic treatment
[作者：Palmowski, M; Huppert, J; Hauff, P; Reinhardt, M; Schreiner, K; Socher, MA; Hallscheidt, P; Kauffmann, GW; Semmler, W; Kiessling, F,期刊：Cancer research, 页码：7042-7049 , 文章类型： Article，,卷期：2008年68-17]
- High-frequency volumetric Power Doppler ultrasound (HF-VPDU) captures flow-dependent signals in blood vessels and can be used to assess antiangiogenic therapy effects in rodent tumors. However, the sensitivity is limited...
- Gemcitabine and cytosine arabinoside cytotoxicity: Association with lymphoblastoid cell expression
[作者：Li, L; Fridley, B; Kalari, K; Jenkins, G; Batzler, A; Safgren, S; Hildebrandt, M; Ames, M; Schaid, D; Wang, LW,期刊：Cancer research, 页码：7050-7058 , 文章类型： Article，,卷期：2008年68-17]
- Two cytidine analogues, gemcitabine (dFdC) and 1-beta-D-arabinofuranosylcytosine (AraC), show significant therapeutic effect in a variety of cancers. However, response to these drugs varies widely. Evidence from tumor bi...
- Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif
[作者：Curnis, F; Sacchi, A; Gasparri, A; Longhi, R; Bachi, A; Doglioni, C; Bordignon, C; Traversari, C; Rizzardi, GP; Corti, A,期刊：Cancer research, 页码：7073-7082 , 文章类型： Article，,卷期：2008年68-17]
- Asparagine deamidation in peptides or in fibronectin fragments containing the asparagine-glycine-arginine sequence generates isoaspartate-glycine-arginine (isoDGR), a new alpha v beta 3 integrin-binding motif. Because al...
- Podoplanin is a novel Fos target gene in skin carcinogenesis
[作者：Durchdewald, M; Guinea-Viniegra, J; Haag, D; Riehl, A; Lichter, P; Hahn, M; Wagner, EF; Angel, P; Hess, J,期刊：Cancer research, 页码：6877-6883 , 文章类型： Article，,卷期：2008年68-17]
- Expression and function of the oncogenic transcription factor activator protein (A-P-1; mainly composed of Jun and Fos proteins) is required for neoplastic transformation of keratinocytes in vitro and tumor promotion as ...
- BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair
[作者：Cramer, K; Nieborowska-Skorska, M; Koptyra, M; Slupianek, A; Penserga, ETP; Eaves, CJ; Aulitzky, W; Skorski, T,期刊：Cancer research, 页码：6884-6888 , 文章类型： Article，,卷期：2008年68-17]
- Myeloproliferative disorders (MPD) are stem cell-derived clonal diseases arising as a consequence of acquired aberrations in c-ABL, Janus-activated kinase 2 (JAK2), and platelet-derived growth factor receptor (PDGFR) tha...
- Efficient cross-presentation depends on autophagy in tumor cells
[作者：Li, YH; Wang, LX; Yang, GJ; Hao, F; Urba, WJ; Hu, HM,期刊：Cancer research, 页码：6889-6895 , 文章类型： Article，,卷期：2008年68-17]
- Cross-presentation of antigens is critical for the induction of adaptive immunity against tumor cells and infectious pathogens. Currently, it is not known how cross-presentation of tumor antigens is regulated by autophag...
- Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation
[作者：Byron, SA; Gartside, MG; Wellens, CL; Mallon, MA; Keenan, JB; Powell, MA; Goodfellow, PJ; Pollock, PM,期刊：Cancer research, 页码：6902-6907 , 文章类型： Article，,卷期：2008年68-17]
- KRAS activation and PTEN inactivation are frequent events in endometrial tumorigenesis, occurring in 10% to 30% and 26% to 80% of endometrial cancers, respectively. Because we have recently shown activating mutations in ...
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