- Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy
[作者:Hsu, KF; Wu, CL; Huang, SC; Hsieh, JL; Huang, YS; Chen, YF; Shen, MR; Chung, WJ; Chou, CY; Shiau, AL,期刊:Cancer gene therapy, 页码:526-534 , 文章类型: Article,,卷期:2008年15-8]
- Cervical cancer is the second most common type of malignant tumor among women worldwide. When the disease is confined locally, it can be controlled with surgical resection and radiotherapy. However, patients with recurre...
- Antiangiogenic systemic gene therapy combined with doxorubicin administration induced caspase 8 and 9-mediated apoptosis in endothelial cells and an anti-metastasis effect
[作者:Peled, M; Shaish, A; Greenberger, S; Katav, A; Hodish, I; Ben-Shushan, D; Barshack, I; Mendel, I; Frishman, L; Tal, R; Bangio, L; Breitbart, E; Harats, D,期刊:Cancer gene therapy, 页码:535-542 , 文章类型: Article,,卷期:2008年15-8]
- Ad-PPE-Fas-c is an adenovector that expresses Fas-c under the control of the modified pre-proendothelin-1 (PPE-1) promoter. Fas-c is a chimeric death receptor containing the extracellular portion of tumour necrosis facto...
- Systemic delivery of HK Raf-1 siRNA polyplexes inhibits MDA-MB-435 xenografts
[作者:Leng, Q; Scaria, P; Lu, P; Woodle, MC; Mixson, AJ,期刊:Cancer gene therapy, 页码:485-495 , 文章类型: Article,,卷期:2008年15-8]
- Our past research has focused on identifying an effective carrier composed of histidine and lysine for delivery of nucleic acid into cells. For this purpose, we developed histidine-lysine-rich (HK) polymers with specific...
- In vivo persistence of genetically modified T cells generated ex vivo using the fibronectin CH296 stimulation method
[作者:Yu, S; Nukaya, I; Enoki, T; Chatani, E; Kato, A; Goto, Y; Dan, K; Sasaki, M; Tomita, K; Tanabe, M; Chono, H; Mineno, J; Kato, I,期刊:Cancer gene therapy, 页码:508-516 , 文章类型: Article,,卷期:2008年15-8]
- Recombinant human fibronectin fragment (FN-CH296, RetroNectin) has been widely used for retroviral gene therapy to enhance gene transfer efficiency. Based on the observation that immobilized FN-CH296 together with anti-C...
- Effects of DNAzymes targeting Aurora kinase A on the growth of human prostate cancer
[作者:Qu, Y; Zhang, L; Mao, M; Zhao, F; Huang, X; Yang, C; Xiong, Y; Mu, D,期刊:Cancer gene therapy, 页码:517-525 , 文章类型: Article,,卷期:2008年15-8]
- Aurora kinase A has been demonstrated to be involved in the malignant progression of many types of cancer including prostate cancer, we therefore hypothesized that Aurora kinase A might work as a valuable target for pros...
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