- Multiple states of a nucleotide-bound group 2 chaperonin
[作者:Clare, DK; Stagg, S; Quispe, J; Farr, GW; Horwich, AL; Saibil, HR,期刊:Structure, 页码:528-534 , 文章类型: Article,,卷期:2008年16-4]
- Chaperonin action is controlled by cycles of nucleotide binding and hydrolysis. Here, we examine the effects of nucleotide binding on an archaeal group 2 chaperonin. In contrast to the ordered apo state of the group 1 ch...
- Structure of the mammalian 80S ribosome at 8.7 angstrom resolution
[作者:Chandramouli, P; Topf, M; Menetret, JF; Eswar, N; Cannone, JJ; Gutell, RR; Sali, A; Akey, CW,期刊:Structure, 页码:535-548 , 文章类型: Article,,卷期:2008年16-4]
- In this paper, we present a structure of the mammalian ribosome determined at similar to 8.7 angstrom resolution by electron cryomicroscopy and single-particle methods. A model of the ribosome was created by docking homo...
- Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding
[作者:Lambert, AR; Sussman, D; Shen, B; Maunus, R; Nix, J; Samuelson, J; Xu, SY; Stoddard, BL,期刊:Structure, 页码:558-569 , 文章类型: Article,,卷期:2008年16-4]
- The structure of the rare-cutting restriction endonuclease NotI, which recognizes the 8 by target 5'-GCG GCCGC-3', has been solved with and without bound DNA. Because of its specificity (recognizing a site that occurs on...
- The evolutionarily conserved family of cyanovirin-N homologs: Structures and carbohydrate specificity
[作者:Koharudin, LMI; Viscomi, AR; Jee, JG; Ottonello, S; Gronenborn, AM,期刊:Structure, 页码:570-584 , 文章类型: Article,,卷期:2008年16-4]
- Solution structures for three members of the recently discovered cyanovirin-N (CV-N) homolog family of lectins have been determined. Cyanovirin-N homologs (CVNHs) from Tuber borchii, Ceratopteris richardii, and Neurospor...
- The GTPase cycle of the chloroplast import receptors Toc33/Toc34: Implications from monomeric and dimeric structures
[作者:Koenig, P; Oreb, M; Hofle, A; Kaltofen, S; Rippe, K; Sinning, I; Schleiff, E; Tews, I,期刊:Structure, 页码:585-596 , 文章类型: Article,,卷期:2008年16-4]
- Transport of precursor proteins across chloroplast membranes involves the GTPases Toc33/34 and Toc159 at the outer chloroplast envelope. The small GTPase Toc33/34 can homodimerize, but the regulation of this interaction ...
- Crystal structure of human factor VIII: Implications for the formation of the factor IXa-factor VIIIa complex
[作者:Ngo, JCK; Huang, M; Roth, DA; Furie, BC; Furie, B,期刊:Structure, 页码:597-606 , 文章类型: Article,,卷期:2008年16-4]
- Factor VIII is a procofactor that plays a critical role in blood coagulation, and is missing or defective in hemophilia A. We determined the X-ray crystal structure of B domain-deleted human factor VIII. This protein is ...
- Coarse-grained MD simulations of membrane protein-bilayer self-assembly
[作者:Scott, KA; Bond, PJ; Ivetac, A; Chetwynd, AP; Khalid, S; Sansom, MSP,期刊:Structure, 页码:621-630 , 文章类型: Article,,卷期:2008年16-4]
- Complete determination of a membrane protein structure requires knowledge of the protein position within the lipid bilayer. As the number of determined structures of membrane proteins increases so does the need for compu...
- Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation
[作者:Puorger, C; Eidam, O; Capitani, G; Erilov, D; Grutter, MG; Glockshuber, R,期刊:Structure, 页码:631-642 , 文章类型: Article,,卷期:2008年16-4]
- Adhesive type 1 pili from uropathogenic Escherichia coli strains are heat and denaturant resistant, filamentous protein complexes. Individual pilus subunits associate through "donor strand complementation," whereby the i...
- Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300
[作者:Zeng, L; Zhang, Q; Gerona-Navarro, G; Moshkina, N; Zhou, MM,期刊:Structure, 页码:643-652 , 文章类型: Article,,卷期:2008年16-4]
- Histone lysine acetylation is central to epigenetic control of gene transcription. Bromodomains of chromosomal proteins function as acetyl-lysine (Kac) binding domains. However, how bromodomains recognize site-specific h...
- NotI is not boring
[作者:Tamulaitiene, G; Siksnys, V,期刊:Structure, 页码:497-498 , 文章类型: Editorial Material,,卷期:2008年16-4]
- Crystal structures of the restriction endonuclease NotI in free and DNA bound forms, presented in this issue of Structure (Lambert et al., 2008), provide a unique insight into the structural details of 8 base pair sequen...
- Exit biology: Battle for the nascent chain
[作者:Selmer, M; Liljas, A,期刊:Structure, 页码:498-500 , 文章类型: Editorial Material,,卷期:2008年16-4]
- Ban and coworkers at ETH are step-by-step widening the perspective of the actions on the ribosome (Bingel-Erienmeyer et al., 2008). The last one in the series is the localization of the binding site of peptide deformylas...
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