Diabetic retinopathy is a progressive disease elicited by chronic exposure to high blood glucose, e.g., hyperglycemia and is generally recognized as a vascular disease like other diabetes-related diseases. Although th...

Compounds that can produce potent biological effects in cells encompass a variety of structural motifs. Many of these compounds share a structural feature that has rarely been noted. It is an allylic cluster of atoms,...

Labedipinedilol-A, a novel dihydropyridine-type calcium antagonist with alpha/beta-adrenoceptor blocking properties, has been reported to produce a cardioprotective effect against ischemia reperfusion injury in rats. ...

The aim of the present study was to investigate the suitability of the melt sonocrystallization technique to modify the undesirable properties of the nonsteroidal anti-inflammatory drug (NSAID), flurbiprofen (FBP), e....

P-glycoprotein, a plasma membrane protein overexpressed in multidrug-resistant (MDR) cells, is responsible for the energy-dependent efflux of structurally unrelated cytotoxic agents and MDR-reversing drugs from the ce...