- Behavioral and biochemical effects of Kaixin-San, a traditional Chinese medicinal empirical formula
[作者:Hu, Y; Liu, P; Dai-Hong, G; Rahman, K; Wang, DX; Chen, ML; Xie, TT,期刊:Drug Development Research, 页码:267-271 , 文章类型: Article,,卷期:2008年69-5]
Kaixin-San (KXS), a traditional Chinese medicine, has been used in the treatment of depression. The present study was undertaken to investigate the effects of an ethanolic extract of KXS (KXSE) in mouse models of depr...
- Hydrophobicity predicts in vivo F-19 magnetic resonance detectability of fluorinated psychiatric drugs: Simple test for likely success in clinical pharmacokinetic studies
[作者:Reid, DG; Murphy, PS,期刊:Drug Development Research, 页码:279-283 , 文章类型: Article,,卷期:2008年69-5]
The F-19 NMR signal half-height linewidths of six fluorinated psychiatric pharmaceuticals, on which successful in vivo magnetic resonance (MR) studies have been reported (fenfluramine, fluvoxamine, fluoxetine, trifluo...
- A new telomerase inhibitor and apoptosis-inducing agent in leukemia: Perylene derivative G-quadruplex ligand Tel03
[作者:Chu, B; Yuan, G; Zhou, J; Ou, Y; Zhu, P,期刊:Drug Development Research, 页码:235-241 , 文章类型: Article,,卷期:2008年69-5]
Tel03 (N,N'-Bis-(2-(dimethylamino)ethyl)-3,4,9,10-perylentetra-carboxylic acid diimide), a perylene derivative, was synthesized and its interaction with different forms of human telomeric DNA examined. The effect of T...
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