Postoperative ileus (POI), a transient impairment of bowel function, is considered an inevitable response after open abdominal surgery. it leads to significant patient morbidity and increased hospital costs and length...
Background: In the past years the bone seeking radiopharmaceutical samarium lexidronam (Sm-153-EDTMP) has been increasingly used alone or in conjunction with chemotherapy and/or bisphosphonates for the treatment of pa...
Background: Acute graft-versus-host disease (GVHD) is one of the most severe complications following allogeneic transplantation and the involvement of the gut has been associated with increased mortality and a poorer ...
Background: C-C chemokine receptor 2 (CCR2) antagonists belong to a group of chemokine blockers, which represent a new strategy for inflammatory diseases treatment by interfering with the complex system of chemokines ...
Background: beta-Adrenergic receptor antagonists (beta-blockers) have a well-recognised anti hypertensive action that is mediated through a reduction in cardiac output and in the release of renin from the kidneys and ...
Background: In this review we provide the reader with an analysis of the importance of VEGF in modulating the angiogenic process in vascular diseases. Objectives: We have described the key role of VEGF in the developm...
Background: Myocardial infarction (MI) is a leading cause of death among adults and MI survivors have increased risk of developing heart failure. MI is accompanied by acute sympathetic nervous system activation, which...
Background: Checkpoint kinase 1 (Chk1), a serine/threonine kinase, functions as a regulatory kinase in cell cycle progression and is a critical effector of the DNA-damage response. Inhibitors of Chk1 are known to sens...
Background: Although carcinogenesis and cancer have been studied intensively for > 50 years, the rates of cancer incidence and mortality remain high. The most successful approach for reducing these rates has been p...
Background: Botanicals and herbal combinations are among the most common complementary and alternative medicine (CAM) approaches used by cancer patients both for cancer treatment and management of cancer symptoms. Des...