- Genetic Ablation of the Aryl Hydrocarbon Receptor Causes Cigarette Smoke-induced Mitochondrial Dysfunction and Apoptosis
[作者:de Souza, AR; Zago, M; Pollock, SJ; Sime, PJ; Phipps, RP; Baglole, CJ,期刊:Journal of Biological Chemistry, 页码:43214-43228 , 文章类型: Article,,卷期:2011年286-50]
- Cigarette smoke is the primary risk factor for chronic obstructive pulmonary disease (COPD). Alterations in the balance between apoptosis and proliferation are involved in the etiology of COPD. Fibroblasts and epithelial...
- Identification of P-Rex1 as a Novel Rac1-Guanine Nucleotide Exchange Factor (GEF) That Promotes Actin Remodeling and GLUT4 Protein Trafficking in Adipocytes
[作者:Balamatsias, D; Kong, AM; Waters, JE; Sriratana, A; Gurung, R; Bailey, CG; Rasko, JEJ; Tiganis, T; Macaulay, SL; Mitchell, CA,期刊:Journal of Biological Chemistry, 页码:43229-43240 , 文章类型: Article,,卷期:2011年286-50]
- Phosphoinositide 3-kinase (PI3K) signaling promotes the translocation of the glucose transporter, GLUT4, to the plasma membrane in insulin-sensitive tissues to facilitate glucose uptake. In adipocytes, insulin-stimulated...
- Assembly of Preactivation Complex for Urease Maturation in Helicobacter pylori CRYSTAL STRUCTURE OF UreF-UreH PROTEIN COMPLEX
[作者:Fong, YH; Wong, HC; Chuck, CP; Chen, YW; Sun, HZ; Wong, KB,期刊:Journal of Biological Chemistry, 页码:43241-43249 , 文章类型: Article,,卷期:2011年286-50]
- Colonization of Helicobacter pylori in the acidic environment of the human stomach depends on the neutralizing activity of urease. Activation of apo-urease involves carboxylation of lysine 219 and insertion of two nickel...
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